CAS 4465-65-0

(1R,4aS,12aS)-3-[ammino(idrossi)metilidene]-4a,6,7-triidrossi-N,N,11-trimetil-2,4,5-triosso-1,2,3,4,4a,5,12,12a-ottahidrotetracen-1-ammonio

Descrizione:

La sostanza chimica con il nome "(1R,4aS,12aS)-3-[ammino(idrossi)metilidene]-4a,6,7-triidrossi-N,N,11-trimetil-2,4,5-triosso-1,2,3,4,4a,5,12,12a-ottahidrotetracen-1-ammonio" e numero CAS 4465-65-0 è un composto organico complesso caratterizzato dalla sua intricatissima struttura policiclica e da molteplici gruppi funzionali. Presenta un quadro tetraciclico con diversi gruppi idrossile (-OH) e amminici (-NH2), contribuendo alla sua potenziale solubilità in solventi polari e attività biologica. La presenza di gruppi triossido indica un alto grado di ossidazione, che può influenzare la sua reattività e stabilità. La stereochimica specifica, denotata dalle configurazioni R e S, suggerisce che il composto possa presentare proprietà chirali, potenzialmente influenzando le sue interazioni nei sistemi biologici. Questo composto potrebbe essere di interesse nella chimica medicinale a causa della sua complessità strutturale e della presenza di gruppi funzionali che potrebbero partecipare a varie interazioni biochimiche. Tuttavia, sarebbero necessari studi dettagliati per comprendere appieno le sue proprietà, reattività e potenziali applicazioni.

Formula: C₂₂H₂₃N₂O₇

InChI: InChI=1/C22H22N2O7/c1-8-9-5-4-6-12(25)13(9)17(26)14-10(8)7-11-16(24(2)3)18(27)15(21(23)30)20(29)22(11,31)19(14)28/h4-6,11,16,25-26,30-31H,7,23H2,1-3H3/p+1/t11-,16+,22-/m0/s1

4-EPIANHYDROTETRACYCLINE HYDROCHLORIDE CRS

CAS: 4465-65-0

4-EPIANHYDROTETRACYCLINE HYDROCHLORIDE CRS

Formula: C₂₂H₂₃ClN₂O₇

Colore e forma: Orange. Powder.

Peso molecolare: 462.8802

Ref: 41-E0400000

4-Epianhydrotetracycline Hydrochloride

CAS: 4465-65-0

Tetracyclines and their derivatives; salts thereof

Formula: C₂₂H₂₂N₂O₇·HCl

Colore e forma: Dark Yellow Brown Solid

Peso molecolare: 426.1427

Ref: 45-1236506

4-Epianhydrotetracycline hydrochloride

CAS: 4465-65-0

EATC, a tetracycline byproduct, combats Pseudomonas to E. coli with MIC50s of 0.75-16 mg/L.

Formula: C₂₂H₂₃ClN₂O₇

Colore e forma: Solid

Peso molecolare: 462.88

Ref: TM-T36599

4-Epianhydrotetracycline hydrochloride

Prodotto controllato

CAS: 4465-65-0

Formula: C₂₂H₂₂N₂O₇·ClH

Colore e forma: Neat

Peso molecolare: 462.88

Ref: 04-C13174500

Tetracycline EP Impurity D HCl (Chlortetracycline EP Impurity I HCl , Lymecycline EP Impurity D HCl , 4-Epianhydrotetracycline HCl )

CAS: 4465-65-0

Formula: C₂₂H₂₂N₂O₇·HCl

Peso molecolare: 426.43 36.46

Ref: 4Z-T-4035

4-Epianhydrotetracycline Hydrochloride Hydrate (>85%)

Prodotto controllato

CAS: 4465-65-0

Applications An antibiotic derived from Tetracycline. Studies have shown that this derivative can have a 250-fold higher toxicity depending on the system under study. This compound is a contaminant of emerging concern (CECs).
References Simmons, D., et al.: J. Pharm. Sci., 55, 1313 (1966), Paemen, L., et al.: Biochem. Pharmacol., 52, 105 (1996),

Formula: C₂₂H₂₂N₂O₇·HCl·H₂O

Purezza: >85%

Colore e forma: Neat

Peso molecolare: 462.88

Ref: TR-E578070

4-Epianhydrotetracycline hydrochloride

CAS: 4465-65-0

4-Epianhydrotetracycline hydrochloride is a chemically modified antibiotic derivative, originating from the structural transformation of tetracycline. It is derived through epimerization and dehydration processes, which alter the parent compound's structure.

Formula: C₂₂H₂₃ClN₂O₇

Purezza: Min. 95%

Peso molecolare: 462.9 g/mol

Ref: 3D-EAA46565

Tetracycline EP Impurity D

CAS: 4465-65-0

Formula: C₂₂H₂₂N₂O₇HCl

Peso molecolare: 426.4 : 36.46

Ref: ST-EA-CP-T200006

4-Epianhydrotetracycline hydrochloride hydrate

CAS: 4465-65-0, 7518-17-4

4-Epianhydrotetracycline hydrochloride hydrate is a chemical compound that inhibits the activation of protein kinase C (PKC) and blocks the apoptosis pathway. It has been shown to induce apoptosis in prostate cancer cells and also inhibits the proliferation of human microvessel endothelial cells. 4-Epianhydrotetracycline hydrochloride hydrate is stable in both human serum and wastewater, which makes it an ideal drug for treating many types of cancers. It is also used in pharmaceutical drugs as a cytochalasin, which are used to treat angina pectoris by reducing oxygen uptake by erythrocytes, thereby inhibiting oxidative phosphorylation. 4-Epianhydrotetracycline hydrochloride hydrate prevents mitochondrial cytochrome c release, thus blocking the apoptotic pathway in cells. This chemical compound may act as a regulatory molecule that affects energy metabolism and epidermal growth factor (EGF)

Formula: C₂₂H₂₃ClN₂O₇

Purezza: Min. 95%

Peso molecolare: 462.88 g/mol

Ref: 3D-FE22716