CAS 4530-20-5

N-(tert-butossicarbonil)glicina

Descrizione:

N-(tert-butossicarbonil)glicina, comunemente noto come Boc-glicina, è un derivato di amminoacido caratterizzato dalla presenza di un gruppo protettivo tert-butilossicarbonile (Boc) attaccato al gruppo amminico della glicina. Questo composto è tipicamente un solido bianco a bianco sporco ed è solubile in solventi organici polari come il metanolo e il dimetilsolfossido (DMSO), ma meno solubile in solventi non polari. Il gruppo Boc funge da moiety protettivo che stabilizza il gruppo amminico durante la sintesi dei peptidi, consentendo reazioni selettive senza interferire con la funzionalità amminica. La Boc-glicina è ampiamente utilizzata nella sintesi organica, in particolare nella preparazione di peptidi e altre molecole complesse. La sua stabilità in varie condizioni di reazione la rende un intermedio prezioso in applicazioni farmaceutiche e biochimiche. Inoltre, può essere deprotetta in condizioni acide leggere, rigenerando il gruppo amminico libero per ulteriori reazioni. In generale, la Boc-glicina è un composto essenziale nel campo della chimica organica sintetica e della sintesi di peptidi.

Formula: C₇H₁₃NO₄

InChI: InChI=1S/C7H13NO4/c1-7(2,3)12-6(11)8-4-5(9)10/h4H2,1-3H3,(H,8,11)(H,9,10)

InChI key: InChIKey=VRPJIFMKZZEXLR-UHFFFAOYSA-N

SMILES: O(C(NCC(O)=O)=O)C(C)(C)C

Sinonimi:

• (tert-Butoxycarbonyl)aminoacetic acid
• (tert-Butoxycarbonyl)glycine
• 2-(tert-Butoxycarbonylamino)acetic acid
• 2-[(2-Methylpropan-2-yl)oxycarbonylamino]acetic acid
• Boc-<span class="text-smallcaps">L</span>-glycine
• Boc-Gly-OH
• Boc-Gly-OH~N-(tert-Butoxycarbonyl)glycine
• Glycine, N-[(1,1-dimethylethoxy)carbonyl]-
• Glycine, N-carboxy-, N-tert-butyl ester
• N-(terc-butoxicarbonil)glicina
• N-(tert-Butoxycarbonyl)glycin
• N-(tert-Butoxycarbonyl)glycine
• N-Boc-glycine
• N-[(1,1-Dimethylethoxy)carbonyl]glycine
• N-[(tert-Butyloxy)carbonyl]glycine
• N-[[(1,1-Dimethylethyl)oxy]carbonyl]glycine
• N-t-Butyloxycarbonylglycine
• N-tert-Butoxycarbonyl-2-aminoacetic acid
• N-tert-Butoxycarbonylglycine
• N^α-tert-Butyloxycarbonylglycine
• Nsc 127669
• NtertButoxycarbonylglycine
• Nα-tert-Butyloxycarbonylglycine
• [(Tert-Butoxycarbonyl)Amino]Acetate
• t-Butyloxycarbonylglycine

N-(tert-Butoxycarbonyl)glycine

CAS: 4530-20-5

Formula: C₇H₁₃NO₄

Purezza: >98.0%(T)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 175.18

Ref: 3B-B1185

N-Boc-glycine, 98+%

CAS: 4530-20-5

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₇H₁₃NO₄

Purezza: 98+%

Colore e forma: Crystals or powder or crystalline powder, White

Peso molecolare: 175.18

Ref: 02-A11579

Boc-Gly-OH

CAS: 4530-20-5

M03287 - Boc-Gly-OH

Formula: C₇H₁₃NO₄

Purezza: 97%

Colore e forma: Solid, Powder or Crystalline Powder

Peso molecolare: 175.184

Ref: 10-M03287

Boc-Gly-OH

CAS: 4530-20-5

Bachem ID: 4001229.

Formula: C₇H₁₃NO₄

Purezza: > 99%

Colore e forma: White

Peso molecolare: 175.19

Ref: 01-4001229

Boc-Glycine

CAS: 4530-20-5

Formula: C₇H₁₃NO₄

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 175.1824

Ref: IN-DA0034JU

[(t-Butoxycarbonyl)amino]acetic acid

CAS: 4530-20-5

[(t-Butoxycarbonyl)amino]acetic acid

Formula: C₇H₁₃NO₄

Purezza: 97%

Colore e forma: white solid

Peso molecolare: 175.18241g/mol

Ref: 54-OR323299

Boc-Gly-OH

CAS: 4530-20-5

Formula: (CH₃)₃COCONHCH₂CO₂H

Peso molecolare: 175.18

Ref: 7W-GM7526

BOC-Glycine extrapure, 99%

CAS: 4530-20-5

Formula: C₇H₁₃NO₄

Purezza: min. 99%

Colore e forma: White, Crystalline powder

Peso molecolare: 175.20

Ref: SR-71943

N-Boc-glycine

Prodotto controllato

CAS: 4530-20-5

Applications Used in the composition of drugs containing Ketoprofen, and Sodium hyaluronate as antiinflammatory agents.
References Bajusz, S., et al.: J. Med. Chem., 33, 1729 (1990), Dahlgren, A., et al.: Bioorg. Med. Chem., 10, 1829 (2002),

Formula: C₇H₁₃NO₄

Colore e forma: Neat

Peso molecolare: 175.18

Ref: TR-B656125

Boc-Gly-OH

CAS: 4530-20-5

Boc-Gly-OH is a cyclic peptide with a fatty acid acyl chain. It is synthesized by reacting the amino acid glycine with sodium carbonate in the presence of trifluoroacetic acid to form the intermediate Boc-Gly-OSu. The product is then reacted with allyl bromide in a second step to produce Boc-Gly-OCH2CH2Br and then reacted with calcium chloride to yield the final product. Boc-Gly-OH has been used as an HIV inhibitor, which may be due to its ability to bind to both CD4 and gp120 proteins on the surface of HIV. This binding inhibits viral entry into host cells by blocking protease activity and fusion of viral envelope with host cell membrane, leading to inhibition of HIV infection.

Formula: C₇H₁₃NO₄

Purezza: Min. 95%

Peso molecolare: 175.18 g/mol

Ref: 3D-BLG-2054

N-Boc-glycine

CAS: 4530-20-5

N-Boc-glycine is a chemical compound used in the synthesis of cyclic peptides. N-Boc-glycine is synthesized by the reaction of glycine with methanol and hydrochloric acid in the presence of an activated form of carbon monoxide. The pharmacokinetic properties of N-Boc-glycine are similar to those for human immunoglobulin, and it can be used as a reference compound for preparative high performance liquid chromatography (HPLC). It has been shown that the nitrogen atoms in N-Boc-glycine are chemically stable, which makes it suitable for asymmetric synthesis. N-Boc-glycine also has potent antagonist effects on biochemical properties such as calcium channel blockade, inhibition of platelet aggregation, and inhibition of neutrophil chemotaxis.

Formula: C₇H₁₃NO₄

Purezza: Min. 95%

Colore e forma: White Powder

Peso molecolare: 175.18 g/mol

Ref: 3D-FB18945