CAS 465-99-6

Hederagenina

Descrizione:

Hederagenina è una saponina triterpenoide, specificamente un composto pentaciclico, che deriva principalmente da varie fonti vegetali, inclusa l'edera (Hedera helix). È caratterizzato dalla sua struttura simile agli steroidi, con un sistema di anelli fusi che contribuisce alla sua attività biologica. Hederagenina presenta una gamma di proprietà farmacologiche, inclusi effetti anti-infiammatori, antiossidanti e potenziali effetti anticancro, rendendolo di interesse nella chimica medicinale e nella ricerca di prodotti naturali. Il composto si trova tipicamente sotto forma di glicosidi, che possono migliorare la sua solubilità e biodisponibilità. In termini di proprietà fisiche, Hederagenina è generalmente una polvere bianca o bianco sporco, ed è solubile in solventi organici ma ha una solubilità limitata in acqua. La sua formula molecolare riflette un complesso arrangiamento di atomi di carbonio, idrogeno e ossigeno, tipico dei triterpenoidi. La ricerca continua a esplorare i suoi meccanismi d'azione e le potenziali applicazioni terapeutiche, in particolare nel contesto della medicina tradizionale e della farmacologia moderna.

Formula: C₃₀H₄₈O₄

InChI: InChI=1S/C30H48O4/c1-25(2)13-15-30(24(33)34)16-14-28(5)19(20(30)17-25)7-8-22-26(3)11-10-23(32)27(4,18-31)21(26)9-12-29(22,28)6/h7,20-23,31-32H,8-18H2,1-6H3,(H,33,34)/t20-,21+,22+,23-,26-,27-,28+,29+,30-/m0/s1

InChI key: InChIKey=PGOYMURMZNDHNS-MYPRUECHSA-N

SMILES: C[C@]12C([C@]3([C@@](C(O)=O)(CC1)CCC(C)(C)C3)[H])=CC[C@]4([C@@]2(C)CC[C@@]5([C@]4(C)CC[C@H](O)[C@]5(CO)C)[H])[H]

Sinonimi:

• (3-beta,4-alpha)-3,23-Dihydroxyolean-12-en-28-oic acid
• (3Beta)-3,23-Dihydroxyolean-12-En-28-Oic Acid
• (3Beta)-3,24-Dihydroxyolean-12-En-28-Oic Acid
• (3Beta,5Xi,9Xi,18Xi)-3,23-Dihydroxyolean-12-En-28-Oic Acid
• (3beta,4alpha)-3,23-Dihydroxyolean-12-en-28-oic acid
• (3β,4α)-3,23-Dihydroxyolean-12-en-28-oic acid
• 3β,23-Dihydroxyolean-12-en-28-oic acid
• Astrantiagenin E
• Caulosapogenin
• Hederagenic acid
• Hederagenine
• Hederagenol
• Helexin
• Nsc 24954
• Olean-12-en-28-oic acid, 3,23-dihydroxy-, (3-beta,4-alpha)-
• Olean-12-en-28-oic acid, 3,23-dihydroxy-, (3beta,4alpha)- (9CI)
• Olean-12-en-28-oic acid, 3,23-dihydroxy-, (3β,4α)-
• Olean-12-en-28-oic acid, 3-beta,23-dihydroxy- (6CI,7CI,8CI)
• Olean-12-en-28-oic acid, 3beta,23-dihydroxy- (8CI)
• Olean-12-en-28-oic acid, 3β,23-dihydroxy-

Hederagenin

CAS: 465-99-6

Formula: C₃₀H₄₈O₄

Purezza: >98.0%(T)(HPLC)

Colore e forma: White to Light yellow powder to crystal

Peso molecolare: 472.71

Ref: 3B-H1645

Hederagenin

CAS: 465-99-6

Hederagenin analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Formula: C₃₀H₄₈O₄

Purezza: (HPLC) ≥98%

Colore e forma: Powder

Peso molecolare: 472.71

Ref: 11-0035S

Hederagenin

CAS: 465-99-6

Hederagenin

Purezza: ≥98%

Peso molecolare: 472.7g/mol

Ref: 54-BUP00171

Hederagenin

CAS: 465-99-6

Formula: C₃₀H₄₈O₄

Peso molecolare: 472.71

Ref: 7W-GY0668

Hederagenin

CAS: 465-99-6

Formula: C₃₀H₄₈O₄

Purezza: 95%~99%

Peso molecolare: 472.71

Ref: BP-BP0710

Hederagenin

CAS: 465-99-6

Hederagenin

Formula: C₃₀H₄₈O₄

Purezza: 98%

Colore e forma: almost white powder

Peso molecolare: 472.70g/mol

Ref: 54-BIDF1006

Hederagenin

CAS: 465-99-6

Hederagenin (Hederagenol) is a triterpenoid saponin inhibiting LPS-stimulated expression of iNOS, COX-2, and NF-κB.

Formula: C₃₀H₄₈O₄

Purezza: 98.47% - 99.11%

Colore e forma: Solid

Peso molecolare: 472.7

Ref: TM-T3039

Hederagenin

CAS: 465-99-6

Carboxylic acid with alcohol function

Formula: C₃₀H₄₈O₄

Purezza: ≥ 90.0 % (HPLC)

Colore e forma: Powder

Peso molecolare: 472.71

Ref: 5G-89706

Hederagenin

CAS: 465-99-6

Applications Triterpenoid which can inhibit the proliferation of leukemia HL-60 cells.
References Cho, J., et al.: Pulmon. Pharmacol. Ther., 23, 190 (2010), Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010), Saha, S., et al.: J. Agric. Food Chem., 58, 434 (2010),

Formula: C₃₀H₄₈O₄

Colore e forma: Neat

Peso molecolare: 472.70

Ref: TR-H129990

Hederagenin

Prodotto controllato

CAS: 465-99-6

Hederagenin is a triterpenoid saponin, which is a naturally occurring organic compound typically found in various plant species, particularly in the Araliaceae family. It is derived from the hydrolysis of saponins such as hederacoside C, present in plants like ivy (Hedera helix). This compound exhibits a wide array of biological activities due to its ability to interact with cellular membranes and proteins.

Formula: C₃₀H₄₈O₄

Purezza: Min. 95.0 Area-%

Colore e forma: White Powder

Peso molecolare: 472.70 g/mol

Ref: 3D-FH23742

Hederagenin

Prodotto controllato

CAS: 465-99-6

Hederagenin is a pentacyclic triterpenoid saponin, which is a naturally occurring compound derived primarily from the plant Hedera helix, commonly known as English ivy. Hederagenin is characterized by its capability to modulate inflammatory pathways and its biological activity against various microorganisms. The mode of action of hederagenin involves the inhibition of specific enzymes and signaling pathways associated with inflammation, such as the NF-κB pathway, which plays a pivotal role in cellular responses. Furthermore, it disrupts microbial cell membranes, leading to reduced microbial viability.

Formula: C₃₀H₄₈O₄

Purezza: Min. 97 Area-%

Peso molecolare: 472.70 g/mol

Ref: 3D-Q-100493

HEDERAGENIN

CAS: 465-99-6

Purezza: 98%

Peso molecolare: 472.7099915

Ref: 10-F859141