CAS 4651-67-6

Acido 7-cheto-litocolico

Descrizione:

Acido 7-cheto-litocolico è un derivato degli acidi biliari che gioca un ruolo nel metabolismo dei lipidi e nella regolazione dei livelli di colesterolo nel corpo. È caratterizzato dal suo gruppo funzionale chetonico nella posizione C7 del nucleo steroideo, che lo distingue da altri acidi biliari. Questo composto si trova tipicamente nella bile di alcuni animali ed è coinvolto nell'emulsificazione dei grassi alimentari, facilitando la loro assorbimento nell'intestino. La sua struttura include uno scheletro steroideo idrofobico, che contribuisce alla sua natura anfipatica, permettendogli di interagire sia con i lipidi che con l'acqua. Acido 7-cheto-litocolico può anche mostrare attività biologiche, inclusi effetti potenziali sul metabolismo dei lipidi e sulla microbiota intestinale. In quanto acido biliare, è soggetto a circolazione enteroepatica, influenzando la sua concentrazione e attività nel tratto gastrointestinale. Comprendere le sue proprietà e funzioni è importante per la ricerca sulla salute gastrointestinale e sui disturbi metabolici.

Formula: C₂₄H₃₈O₄

InChI: InChI=1S/C24H38O4/c1-14(4-7-21(27)28)17-5-6-18-22-19(9-11-24(17,18)3)23(2)10-8-16(25)12-15(23)13-20(22)26/h14-19,22,25H,4-13H2,1-3H3,(H,27,28)/t14-,15+,16-,17-,18+,19+,22+,23+,24-/m1/s1

InChI key: InChIKey=DXOCDBGWDZAYRQ-AURDAFMXSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@]([C@]4(C)[C@](CC3=O)(C[C@H](O)CC4)[H])(CC1)[H])[H])(CC[C@@]2([C@@H](CCC(O)=O)C)[H])[H]

Sinonimi:

• (3Alpha,5Beta)-3-Hydroxy-7-Oxocholan-24-Oic Acid
• (3Alpha,5Beta,8Xi,9Xi,10Xi,13Xi,14Xi,17Xi,20Xi)-3-Hydroxy-7-Oxocholan-24-Oic Acid
• (3α,5β)-3-Hydroxy-7-oxo-Cholan-24-oic acid
• (3α,5β)-3-Hydroxy-7-oxocholan-24-oic acid
• 3-Hydroxy-7-Oxocholan-24-Oic Acid
• 3Alpha-Hydroxy-7-Oxo-5Beta-Cholanic Acid
• 3alpha-Hydroxy-7-oxo-5-cholanic acid
• 3alpha-Hydroxy-7-oxo-5beta-cholic acid
• 3α-Hydroxy-7-keto-5β-cholan-24-oic acid
• 3α-Hydroxy-7-keto-5β-cholanic acid
• 3α-Hydroxy-7-oxo-5β-cholan-24-oic acid
• 3α-Hydroxy-7-oxo-5β-cholan-24-oicacid
• 3α-Hydroxy-7-oxo-5β-cholanic acid
• 3α-Hydroxy-7-oxo-5β-cholanoic acid
• 3α-Hydroxy-7-oxo-5β-cholic acid
• 5β-Cholan-24-oic acid, 3α-hydroxy-7-oxo-
• 5β-Cholanic acid, 3α-hydroxy-7-oxo-
• 5β-Cholanic acid-3α-ol-7-one
• 7-Ketochenodeoxycholic acid
• 7-Ketolithocholic acid
• 7-Oxo-3α-hydroxycholan-24-oic acid
• 7-Oxolithocholic acid
• 7-keto-Lithocholic acid
• 7K-Lca
• Cholan-24-oic acid, 3-hydroxy-7-oxo-, (3α,5β)-
• Hydroxycholanicacid
• NSC 226118
• Nutriacholic acid
• Obeticholic Acid Intermediate

3α-Hydroxy-7-oxo-5β-cholanic Acid

CAS: 4651-67-6

Formula: C₂₄H₃₈O₄

Purezza: >97.0%(T)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 390.56

Ref: 3B-H0869

7-keto Lithocholic Acid

CAS: 4651-67-6

Formula: C₂₄H₃₈O₄

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 390.5561

Ref: IN-DA0035ZB

7-Ketolithocholic acid

CAS: 4651-67-6

7-Ketolithocholic acid

Purezza: ≥98%

Peso molecolare: 390.56g/mol

Ref: 54-BUP18083

Ursodeoxycholic Acid EP Impurity F

CAS: 4651-67-6

Formula: C₂₄H₃₈O₄

Colore e forma: White To Off-White Solid

Peso molecolare: 390.56

Ref: 4Z-U-029

3-α-Hydroxy-7-Keto-5β-Cholanic Acid

CAS: 4651-67-6

3-α-Hydroxy-7-Keto-5β-Cholanic Acid

Purezza: 98%

Peso molecolare: 390.56g/mol

Ref: 54-OR1029775

7-Oxolithocholic Acid

CAS: 4651-67-6

Formula: C24H38O4

Purezza: >98%

Colore e forma: Solid

Peso molecolare: 390.56

Ref: 48-65-1107

Ursodeoxycholic Acid EP Impurity F

CAS: 4651-67-6

Formula: C₂₄H₃₈O₄

Peso molecolare: 390.56

Ref: ST-EA-CP-U1006

Nutriacholic Acid

CAS: 4651-67-6

Impurity Ursodeoxycholic Acid EP Impurity F
Applications Nutriacholic Acid (Ursodeoxycholic Acid EP Impurity F) is derivative of Lithocholic Acid (L469180), a cholic acid derivative as TGR5 modulator.
References Schneider, H., et al.: Bioorg. Med. Chem. Lett., 6, 637 (1996); Takamine, F., et al.: Microbiol. Immunol., 39, 11 (1995); Yamashita, H., et al.: Hepatol., 20, 663 (1994);

Formula: C₂₄H₃₈O₄

Colore e forma: White To Off-White

Peso molecolare: 390.56

Ref: TR-N925550

3a-Hydroxy-7-oxo-5b-cholanic acid

CAS: 4651-67-6

Formula: C₂₄H₃₈O₄

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 390.564

Ref: 10-F242080

Nutriacholic Acid-d5

Prodotto controllato

CAS: 4651-67-6

Formula: C₂₄D₅H₃₃O₄

Colore e forma: Neat

Peso molecolare: 395.587

Ref: TR-N925558

3a-Hydroxy-7-oxo-5b-cholanic acid

Prodotto controllato

CAS: 4651-67-6

3a-Hydroxy-7-oxo-5b-cholanic acid (3OHC) is a metabolite of 7-oxo-5b-cholanate, which is synthesized from cholic acid by the bacterial strain Clostridium species. 3OHC has been shown to be a potent inhibitor of human serum primary sclerosing cholangitis, which is an inflammatory disease of the bile ducts in the liver. It functions by inhibiting the formation of hydroxyl radicals, which are reactive oxygen species that cause tissue injury. The hydroxyl group in 3OHC reacts with the sulfhydryl groups on cysteine residues in proteins and forms sulfenic acids, which react with hydrogen peroxide to form chemically stable products. 3OHC also inhibits bacterial growth by binding to DNA and inhibiting transcription and replication.

Formula: C₂₄H₃₈O₄

Purezza: Min. 95%

Peso molecolare: 390.56 g/mol

Ref: 3D-FH75036

7-Ketolithocholic acid

CAS: 4651-67-6

7-Ketolithocholic acid absorbs and reduces endogenous bile acid and cholesterol secretion.

Formula: C₂₄H₃₈O₄

Purezza: 98.68% - 99.9%

Colore e forma: White - Almost White Solid Powder

Peso molecolare: 390.56

Ref: TM-T13522