CAS 470-40-6

Tujopsene

Descrizione:

Tujopsene è un composto organico naturale classificato come sesquiterpene, derivato principalmente dagli oli essenziali di alcuni alberi conifere, in particolare quelli della famiglia Cupressaceae. È caratterizzato dalla sua complessa struttura biciclica, che contribuisce alle sue uniche proprietà fisiche e chimiche. Tujopsene è tipicamente un liquido incolore o giallo pallido con un aroma caratteristico di legno e terra, rendendolo prezioso nelle industrie delle fragranze e dei sapori. La sua formula molecolare è C15H24 e ha un punto di ebollizione relativamente basso, che consente una facile vaporizzazione. Tujopsene presenta proprietà idrofobiche, rendendolo insolubile in acqua ma solubile in solventi organici. Inoltre, è stato studiato per le sue potenziali attività biologiche, inclusi effetti antimicrobici e anti-infiammatori, sebbene siano necessarie ulteriori ricerche per comprendere appieno il suo potenziale farmacologico. A causa della sua origine naturale e del suo profilo aromatico unico, Tujopsene è spesso utilizzato nella profumeria e come agente aromatizzante naturale.

Formula: C₁₅H₂₄

InChI: InChI=1/C15H24/c1-11-6-9-14(4)8-5-7-13(2,3)15(14)10-12(11)15/h6,12H,5,7-10H2,1-4H3/t12-,14-,15-/m0/s1

InChI key: InChIKey=WXQGPFZDVCRBME-QEJZJMRPSA-N

SMILES: C[C@@]12[C@@]3([C@@](C3)(C(C)=CC1)[H])C(C)(C)CCC2

Sinonimi:

• (1AS-(1aalpha,4abeta,8aR*))-1,1a,4,4a,5,6,7,8-octahydro-2,4a,8,8-tetramethylcyclopropa(d)naphthalene
• (1aS,4aS,8aS)-1,1a,4,4a,5,6,7,8-Octahydro-2,4a,8,8-tetramethylcyclopropa[d]naphthalene
• (1aS,4aS,8aS)-2,4a,8,8-tetramethyl-1,1a,4,4a,5,6,7,8-octahydrocyclopropa[d]naphthalene
• Cyclopropa(d)naphthalene, 1,1a,4,4a,5,6,7,8-octahydro-2,4a,8,8-tetramethyl-, (1aS,4aS,8aS)-
• Cyclopropa[d]naphthalene, 1,1a,4,4a,5,6,7,8-octahydro-2,4a,8,8-tetramethyl-, [1aS-(1aα,4aβ,8aR*)]-
• Nsc 44707
• Sesquichamene
• Thujopsen
• Thujopsene
• Widdrene
• cis-(-)-Thujopsene
• (1S,6S,10S)-2,2,6,9-TETRAMETHYL-TRICYCLO[8.1.0.0(1.6)]UNDEC-8-ENE
• cyclopropa[d]naphthalene,
• [1aS,4aS,8aS,(-)]-1,1a,4,4a,5,6,7,8-Octahydro-2,4aβ,8,8-tetramethylcyclopropa[d]naphthalene
• (1aS,8aS)-1,1aα,4,4a,5,6,7,8-Octahydro-2,4aβ,8,8-tetramethylcyclopropa[d]naphthalene
• 4abeta,8atheta)]-as-(1aalph
• (-)-Thujopsene >=97.0% (GC)
• (Z)-Thujopsene
• THUJOPSEN, (-)-(SG)(CALL)
• (1S,6S,10S)-2,2,6,9-Tetramethyl-1,10-methanobicyclo[4.4.0]deca-8-ene
• Einecs 207-426-8
• THUJOPSEN, (-)-(SG)
• 2,4a,8,8-Tetramethyl-1,1a,4,4a,5,6,7,8-octahydrocyclopropa[d]naphthalene
• Cyclopropa[d]naphthalene, 1,1a,4,4a,5,6,7,8-octahydro-2,4a,8,8-tetramethyl-, [1aS-(1aalpha,4abeta,8aR*)]-

(-)-Thujopsene

CAS: 470-40-6

Formula: C₁₅H₂₄

Colore e forma: Clear, colourless liquid

Peso molecolare: 204.35

Ref: 7W-GL4199

Thujopsene

CAS: 470-40-6

Thujopsene, a sesquiterpene found in T. dolabrata, exhibits a wide range of biological activities. It inhibits Na+/K+-ATPase and cytochrome P450 (CYP) isoform CYP2B6 with IC50 values of 25.9 µg/ml and Ki of 0.8 µM, respectively. Additionally, thujopsene demonstrates antimicrobial efficacy against both Gram-positive and Gram-negative bacteria, such as S. aureus, M. luteus, and S. typhimurium, with MICs ranging from 25-50 µg/ml. It also suppresses antigen-induced β-hexosaminidase release in IgE-sensitized RBL-2H3 mast cells (IC50= 25.1 µM) and shows cytotoxicity against A549 non-small cell lung cancer cells with an LC50 of 35.27 µg/ml. Furthermore, thujopsene causes mortality in mites D. farinae and T. putrescentiae, with LC50s of 9.82 and 10.92 µg/cm2, respectively.

Formula: C₁₅H₂₄

Colore e forma: Solid

Peso molecolare: 204.35

Ref: TM-TN7505

(-)-Thujopsene (>85%)

Prodotto controllato

CAS: 470-40-6

Formula: C₁₅H₂₄

Purezza: >85%

Colore e forma: Colourless

Peso molecolare: 204.35

Ref: TR-T910060

(-)-Thujopsene

CAS: 470-40-6

Thujopsene is a natural compound found in plants, such as Astragalus species. It has been shown to have antimicrobial properties against bacteria. Thujopsene is an alkanoic acid with a chemical formula of CH3(CH2)2OCH2CH=CH(CH3)CO2H. This compound is soluble in organic solvents and can be extracted from plants with methyl myristate or ether. Thujopsene also has been shown to have effects on the activity of enzymes, such as lipase and phospholipase, which may be due to its fatty acid chains. Thujopsene has been used as a starting point for the synthesis of other compounds for use in drug development and analysis techniques, such as gas chromatography-mass spectrometry (GC-MS).

Formula: C₁₅H₂₄

Purezza: Min. 85 Area-%

Colore e forma: Clear Liquid

Peso molecolare: 204.35 g/mol

Ref: 3D-FT171510