CAS 479-18-5

diprofillina

Descrizione:

diprofillina è un derivato della xantina che presenta proprietà broncodilatatrici, rendendolo utile nel trattamento di condizioni respiratorie come l'asma e la broncopneumopatia cronica ostruttiva (BPCO). È caratterizzato dalla sua capacità di rilassare il muscolo liscio bronchiale, migliorando così il flusso d'aria e alleviando i sintomi del broncospasmo. Chimicamente, diprofillina è noto per la sua tossicità relativamente bassa e buona tollerabilità nei pazienti. Ha una solubilità moderata in acqua ed è spesso somministrato per via orale. La sostanza agisce inibendo la fosfodiesterasi, portando a livelli aumentati di AMP ciclico, che contribuiscono ai suoi effetti broncodilatatori. Inoltre, diprofillina può avere lievi proprietà diuretiche e può influenzare la funzione cardiaca. La sua farmacocinetica coinvolge assorbimento, distribuzione, metabolismo ed escrezione, che sono importanti per determinare i regimi di dosaggio. In generale, diprofillina è un agente terapeutico prezioso nella medicina respiratoria, con un profilo che supporta il suo utilizzo nella gestione dell'ostruzione delle vie aeree.

Formula: C₁₀H₁₄N₄O₄

InChI: InChI=1/C10H14N4O4/c1-12-8-7(9(17)13(2)10(12)18)14(5-11-8)3-6(16)4-15/h5-6,15-16H,3-4H2,1-2H3/t6-/m1/s1

InChI key: InChIKey=KSCFJBIXMNOVSH-UHFFFAOYSA-N

SMILES: C(C(CO)O)N1C2=C(N(C)C(=O)N(C)C2=O)N=C1

Sinonimi:

• (Rac)-diprophylline
• 1H-Purine-2,6-dione, 7-(2,3-dihydroxypropyl)-3,7-dihydro-1,3-dimethyl-
• 7-(2,3-Dihydroxypropyl)-1,3-dimethylxanthine
• 7-(2,3-Dihydroxypropyl)-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione
• 7-(2,3-Dihydroxypropyl)theophylline
• 7-(β,γ-Dihydroxypropyl)theophylline
• 7-[(2R)-2,3-dihydroxypropyl]-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione
• 7-[(2S)-2,3-dihydroxypropyl]-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione
• AFI-phyllin
• Airet
• Aristophyllin
• Asthmolysin
• Astmamasit
• Astmophysine
• Astrophyllin
• Athmolysin
• Chlordehydromethyl Testosterone Acetate
• Circain
• Circair
• Cor-Theophyllin
• Cor-Theophylline
• Coronal
• Coronarin
• Corphyllin
• Dilor
• Diphyllin
• Diphylline
• Diphylline (pharmaceutical)
• Diprofilina
• Diprofillin
• Diprophyllin
• Dyphylline
• Emfaseem
• Glyfyllin
• Glyphyllin
• Glyphylline
• Hidroxiteofillina
• Hiphyllin
• Hyphylline
• Isophyllen
• Lufyllin
• Lufyllin-EPG
• Neo-Vasophylline
• Neophyl
• Neophyllin
• Neophyllin M
• Neophylline
• Neostenovasan
• Neothyllin
• Neothylline
• Neotilina
• Neufil
• Neutrafil
• Neutrafillina
• Neutraphyllin
• Neutraphylline
• Neutroxantina
• Nsc 14305
• Nsc 40844
• Prophyllen
• Propyphyllin
• Protheophylline
• Purifilin
• Silbephyllin
• Silbephylline
• Solufilin
• Solufyllin
• Soluphyllin
• Synthophylline
• Tefilan
• Teofen
• Theal
• Theal ampules
• Thefulan
• Thefylan
• Theophylline, 7-(2,3-dihydroxypropyl)-
• 7-(2,3-dihydroxypropyl)-3,7-dihydro-1,3-dimethyl-1h-purine-6-dione
• 7-(BETA,GAMMA-DIHYDROXYPROPYL)-THEOPHYLLINE
• TIMTEC-BB SBB003125
• 1,3-Dimethyl-7-(2,3-dihydroxypropyl)xanthine
• (1,2-Dihydroxy-3-propyl)thiophyllin
• 7-(2,3-Dihydroxypropyl)-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione
• DIPROPYHYLLIN
• 7-(2,3-dihydroxypropyl)-1,3-dimethyl-purine-2,6-dione
• DIPROPHYLLINE
• 7(2,3-dihydroxypropyl)-3,7-dihydro-1,3-dimethyl-1h-purine-6-dione

7-(2,3-Dihydroxypropyl)theophylline

CAS: 479-18-5

Formula: C₁₀H₁₄N₄O₄

Purezza: >98.0%(HPLC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 254.25

Ref: 3B-D3600

Dyphylline

CAS: 479-18-5

An adenosine receptor antagonist, phosphodiesterase inhibitor and vasodilator

Formula: C₁₀H₁₄N₄O₄

Peso molecolare: 254.24

Ref: 02-J63167

DIPROPHYLLINE CRS

CAS: 479-18-5

DIPROPHYLLINE CRS

Formula: C₁₀H₁₄N₄O₄

Colore e forma: Crystalline Powder. White. Whitish. Powder.

Peso molecolare: 254.2426

Ref: 41-D2800000

Dyphylline

CAS: 479-18-5

Theophylline and aminophylline (excluding fenetylline) and their derivatives, salts thereof, not elsewhere specified or included

Formula: C₁₀H₁₄N₄O₄

Colore e forma: White Powder

Peso molecolare: 254.1015

Ref: 45-1231502

Diphylline

CAS: 479-18-5

Formula: C₁₀H₁₄N₄O₄

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 254.2426

Ref: IN-DA006YEZ

Diphylline

CAS: 479-18-5

Diphylline is a bronchodilator with mild vasodilator and diuretic properties, used for asthma, bronchitis, and emphysema.

Formula: C₁₀H₁₄N₄O₄

Purezza: 98.54%

Colore e forma: Crystals From Alcohol Solid

Peso molecolare: 254.24

Ref: TM-T0892

Diprophylline

CAS: 479-18-5

Diprophylline

Purezza: 98%

Peso molecolare: 254.24g/mol

Ref: 54-OR1026964

Diphylline

CAS: 479-18-5

Diphylline

Purezza: ≥98%

Peso molecolare: 254.24g/mol

Ref: 54-BUP18802

Diprophylline (7-(2,3-Dihydroxypropyl)theophylline)

CAS: 479-18-5

Formula: C₁₀H₁₄N₄O₄

Peso molecolare: 254.24

Ref: 7W-GK4515

Diprophylline

Prodotto controllato

CAS: 479-18-5

Formula: C₁₀H₁₄N₄O₄

Colore e forma: Neat

Peso molecolare: 254.24

Ref: 04-C12935000

Diprophylline

Prodotto controllato

CAS: 479-18-5

Formula: C₁₀H₁₄N₄O₄

Colore e forma: Neat

Peso molecolare: 254.24

Ref: 86-MM1191.00

Dyphylline (Diprophylline)

CAS: 479-18-5

Formula: C₁₀H₁₄N₄O₄

Peso molecolare: 254.25

Ref: 4Z-D-112001

Dyphylline

Prodotto controllato

CAS: 479-18-5

Applications Bronchodilator.
References Reitz, C., et al.: Eur. J. Pharm. Sci., 35, 335 (2008), Fliri, A., et al.: J. Med. Chem., 52, 8038 (2009), Dresen, S., et al.: Anal. Bioanal. Chem., 396, 2425 (2010),

Formula: C₁₀H₁₄N₄O₄

Colore e forma: White To Off-White

Peso molecolare: 254.24

Ref: TR-D826500

Dyphylline

Prodotto controllato

CAS: 479-18-5

Dyphylline is a pharmaceutical drug that is used to treat asthma and chronic pulmonary obstructive disease. It is also used as a bronchodilator to relieve the symptoms of asthma and other respiratory disorders by relaxing the air passages. Dyphylline works by increasing the availability of oxygen to the lungs, which helps to relax the muscles around the airways. This leads to an increase in airflow into and out of the lungs. The drug inhibits bacterial growth by inhibiting chemotactic activity and hydroxyl group-dependent reactions, including protein synthesis. It also has potent antimicrobial activity against a wide range of microorganisms, including some strains of bacteria that are resistant to erythromycin and metoprolol succinate, which are two common antibiotics for treating respiratory infections. Dyphylline has been shown to have no effect on human serum albumin levels or on renal function (e.g., glomerular filtration rate).

Formula: C₁₀H₁₄N₄O₄

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 254.24 g/mol

Ref: 3D-FD22634

7-(2,3-Dihydroxypropyl)-1,3-dimethyl-1H-purine-2,6(3H,7H)-dione

CAS: 479-18-5

Formula: C₁₀H₁₄N₄O₄

Purezza: 95.0%

Colore e forma: Solid

Peso molecolare: 254.246

Ref: 10-F464564

Dyphylline

CAS: 479-18-5

Formula: C₁₀H₁₄N₄O₄

Peso molecolare: 254.25

Ref: ST-EA-CP-T59034