CAS 4836-13-9

N4-benzoil-2'-deossicitidina

Descrizione:

N4-benzoil-2'-deossicitidina, con il numero CAS 4836-13-9, è un nucleoside modificato che presenta un gruppo benzilico attaccato all'atomo di azoto nella posizione 4 della base di citidina. Questo composto è caratterizzato dai suoi componenti strutturali, che includono uno zucchero di desossiribosio e una base pirimidinica, specificamente citidina. La modifica benzilica migliora la sua lipofilia e può influenzare la sua attività biologica, rendendolo di interesse nella chimica medicinale e nella biologia molecolare. N4-benzoil-2'-deossicitidina è spesso studiato per le sue potenziali applicazioni in terapie antivirali e anticancro, poiché le modifiche ai nucleosidi possono influenzare la loro interazione con acidi nucleici ed enzimi. Inoltre, questo composto può presentare proprietà uniche di solubilità e stabilità rispetto ai nucleosidi non modificati, il che può essere vantaggioso nella formulazione e somministrazione di farmaci. La sua sintesi coinvolge generalmente l'acilazione della 2′-desossi-citidina e può essere analizzata utilizzando varie tecniche spettroscopiche per confermare la sua struttura e purezza.

Formula: C₁₆H₁₇N₃O₅

InChI: InChI=1/C16H17N3O5/c20-9-12-11(21)8-14(24-12)19-7-6-13(18-16(19)23)17-15(22)10-4-2-1-3-5-10/h1-7,11-12,14,20-21H,8-9H2,(H,17,18,22,23)/t11-,12+,14+/m1/s1

InChI key: InChIKey=MPSJHJFNKMUKCN-OUCADQQQSA-N

SMILES: O=C1N([C@@H]2O[C@H](CO)[C@@H](O)C2)C=CC(NC(=O)C3=CC=CC=C3)=N1

Sinonimi:

• 4-(benzoylamino)-1-(2-deoxy-beta-L-erythro-pentofuranosyl)pyrimidin-2(1H)-one
• 4-N-Benzoyldeoxycytidine
• Benzamide, N-[1-(2-deoxy-β-<span class="text-smallcaps">D</span>-erythro-pentofuranosyl)-1,2-dihydro-2-oxo-4-pyrimidinyl]-
• Cytidine, N-benzoyl-2′-deoxy-
• N-Benzoyl-2′-deoxycytidine
• N-Benzoyldeoxycytidine
• N4-Benzoyl-2'-deoxycytidine
• N⁴-Benzoyl-2′-deoxycytidine
• N⁴-Benzoyldeoxycytidine
• Benzamide, N-[1-(2-deoxy-β-D-erythro-pentofuranosyl)-1,2-dihydro-2-oxo-4-pyrimidinyl]-
• N4-Benzoyldeoxycytidine
• N-Benzoyl-2-Deoxy-Cytidine
• Bz-dC
• DC-N-BZ
• n-benzoyl-2’-deoxy-cytidin
• N(sup 4)benzoyl-2'-deoxycytidine
• NBZ-2'-DC
• N-BZ-DC
• N-[1-(2-Deoxy-β-D-ribofuranosyl)-2-oxo-1,2-dihydropyrimidine-4-yl]benzamide
• N4-BZ-2'-DEOXYCYTIDINE
• DC-BZ 99.0%
• 4-(Benzoylamino)-1-(2-deoxy-beta-L-erythro-pentofuranosyl)-2(1H)-pyrimidinone
• DC-BZ/N-BENZOYL-2''-DEOXY-CYTIDIN
• DC-BZ

N4-Benzoyl-2'-deoxycytidine

CAS: 4836-13-9

Formula: C₁₆H₁₇N₃O₅

Purezza: >98.0%(HPLC)(N)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 331.33

Ref: 3B-B3102

N-Benzoyl-2'-deoxycytidine, 98+%

CAS: 4836-13-9

N-Benzoyl-2'-deoxycytidine, 98+%

Formula: C₁₆H₁₇N₃O₅

Purezza: 98+%

Peso molecolare: 331.33

Ref: 02-H52298

N4-Benzoyl-2'-deoxycytidine

CAS: 4836-13-9

Formula: C₁₆H₁₇N₃O₅

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 331.3233

Ref: IN-DA006WUB

N-Benzoyl-2-Deoxy-Cytidine

CAS: 4836-13-9

N-Benzoyl-2-Deoxy-Cytidine

Purezza: 98%

Peso molecolare: 331.32g/mol

Ref: 54-OR1014255

N4-Benzoyl-2′-deoxycytidine

CAS: 4836-13-9

N4-Benzoyl-2′-deoxycytidine

Purezza: ≥98%

Peso molecolare: 331.32g/mol

Ref: 54-BUP16481

N4-Benzoyl-2''-deoxycytidine

CAS: 4836-13-9

Formula: C₁₆H₁₇N₃O₅

Peso molecolare: 331.33

Ref: 7W-GN9700

N4-Benzoyl-2'-deoxycytidine

CAS: 4836-13-9

Purezza: 98.0%

Colore e forma: Solid, No data available.

Peso molecolare: 331.3280029296875

Ref: 10-F434668

N4-Benzoyl-2′-deoxycytidine

CAS: 4836-13-9

N4-Benzoyl-2′-deoxycytidine is a synthetic nucleoside analog of the natural nucleoside deoxycytidine (dC), a competitive inhibitor of DNA polymerase.

Formula: C₁₆H₁₇N₃O₅

Purezza: 99.41%

Colore e forma: Solid

Peso molecolare: 331.32

Ref: TM-T7961

N4-Benzoyl-2'-deoxycytidine

CAS: 4836-13-9

N4-Benzoyl-2'-deoxycytidine is a fluorescent nucleoside that has been used to study the molecular interactions between sugar residues and the phosphate groups of nucleic acids. It is used as a reagent for glycosidation, which involves the formation of a glycosidic linkage between an alcohol group in a saccharide or oligosaccharide and the hydroxyl group in an aromatic acid. N4-Benzoyl-2'-deoxycytidine has also been synthesized by solid-phase techniques. This synthetic method is based on phosphoramidite chemistry and uses an automated DNA synthesizer to produce oligonucleotides with specific sequences. The synthesis of this nucleoside relies on the use of fluorescent dyes such as fluorescein, rhodamine, and coumarin to monitor progress during synthesis.

Formula: C₁₆H₁₇N₃O₅

Purezza: Min. 95%

Colore e forma: White Powder

Peso molecolare: 331.33 g/mol

Ref: 3D-NB02991

N4-Benzoyl-2'-deoxy-a-cytidine

CAS: 4836-13-9

N4-Benzoyl-2'-deoxy-a-cytidine is a novel, modified nucleoside that has shown anticancer and antiviral activity. It is synthesized by the enzymatic oxidation of 2'-deoxyadenosine with benzoyl chloride and sodium bicarbonate. N4-Benzoyl-2'-deoxy-a-cytidine has been shown to activate transcription, increase DNA synthesis, and inhibit virus replication. It also inhibits bacterial growth, but does not appear to have any effect on mammalian cells.

Formula: C₁₆H₁₇N₃O₅

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 331.32 g/mol

Ref: 3D-NB08374

N-Benzoyldeoxycytidine

Prodotto controllato

CAS: 4836-13-9

Applications N-Benzoyldeoxycytidine is proetected Deoxycytidine (2’-deoxy, D232615) which is a Eg5 kinesin modulator with antiproliferative and apoptosis-inducing activity.
References Hecht, S., et al.: Chem. Res. Toxicol., 17, 588 (2004), Choi, J., et al.: J. Biol. Chem., 281, 38244 (2006), Lao, Y., et al.: Chem. Res. Toxicol., 20, 246 (2007)

Formula: C₁₆H₁₇N₃O₅

Colore e forma: Neat

Peso molecolare: 331.32

Ref: TR-B208000