![[[(1,1-dimethylethoxy)carbonyl]amino]-2,4,5-trifluoro-(R)-benzenebutanoic acid](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fcas-image%2Fthumb-webp%2F19813-boc-r-3-amino-4-245-trifluoro-phenyl-butyric-acid.webp&w=3840&q=75)
CAS 486460-00-8
:acido [(1,1-dimetiletoxicabonil)ammino]-2,4,5-trifluoro-(R)-benzenobutanoico
Descrizione:
La sostanza chimica nota come "acido [(1,1-dimetiletoxicabonil)ammino]-2,4,5-trifluoro-(R)-benzenobutanoico," con il numero CAS 486460-00-8, è un composto organico complesso caratterizzato dai suoi gruppi funzionali unici e dalle caratteristiche strutturali. Contiene un gruppo amminico, un acido carbossilico e un gruppo trifluorometilico, che contribuiscono alla sua reattività e alle potenziali applicazioni in chimica medicinale. La presenza del gruppo 1,1-dimetiletossicarbonilico suggerisce che potrebbe fungere da gruppo protettivo in percorsi sintetici. I sostituenti trifluorometilici aumentano la lipofilia e possono influenzare l'attività biologica, rendendo questo composto di interesse nel design di farmaci. Inoltre, la chiralità indicata dalla configurazione (R) suggerisce che il composto potrebbe presentare proprietà stereospecifiche, che possono essere cruciali per la sua interazione con bersagli biologici. In generale, le caratteristiche distintive di questo composto lo rendono un soggetto prezioso per la ricerca nella sintesi organica e nello sviluppo farmaceutico.
Formula:C15H18F3NO4
InChI:InChI=1/C15H18F3NO4/c1-15(2,3)23-14(22)19-9(6-13(20)21)4-8-5-11(17)12(18)7-10(8)16/h5,7,9H,4,6H2,1-3H3,(H,19,22)(H,20,21)/t9-/m1/s1
SMILES:CC(C)(C)OC(=N[C@H](Cc1cc(c(cc1F)F)F)CC(=O)O)O
Sinonimi:- Boc-(R)-3-Amino-4-(2,4,5-Trifluorophenyl)-butyric acid
- (3R)-N-(Tert-Butoxycarbonyl)-3-Amino-4-(2,4,5-Trifluorophenyl)Butanoic Acid
- (3R)-3-(1,1-Dimethylethoxy Carbonyl) Amino]-4-(2,4,5-Trifluorophenyl) Butanoic Acid
- Boc-(R)-3-Amino-4-(2,4,5-Trifluorophenyl)Butanoic Acid
- (R)-Boc-3-amino-4-(2,4,5-trifluorophenyl)butanoic acid
- (R)-N-Boc-3-Amino-4-(2,4,5-trifluorophenyl)butanoic acid
- (3R)-3-[(tert-butoxycarbonyl)amino]-4-(2,4,5-trifluorophenyl)butanoic acid
- Benzenebutanoic acid,3-[[(1,1-dimethylethoxy)carbonyl]amino]-2,4,5-trifluoro-, (3R)-
- Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acid
- (R)-3-(tert-butoxycarbonylamino)-4-(2,4,5-trifluorophenyl)butanoic acid
- (R)-3-((tert-Butoxycarbonyl)amino)-4-(2,4,5-trifluorophenyl)butanoic acid
- (R)-3-(tert-butoxy carbonylamino)-4-(2,4,5-trifluorophenyl)butanoic acid
- 3(R)-tert-Butoxycarbonylamino-4-(2,4,5-trifluoro-phenyl)-butyric acid
- (R)-3-[(Tert-Butoxycarbonyl)amino]-4-(2,4,5-Trifluoro Phenyl)butanoic Acid
- (Tert-Butoxy)Carbonyl (R)-3-Amino-4-(2,4,5-trifluoro-phenyl)-butyric acid
- 5-TRIFLUORO-PHENYL)-BUTYRIC ACID
- Sitagliptin interMediate
- (3R)-N-Boc-3-amin
- Boc-(R)-3-Amino-4-(2,4,5-Trifluorophenyl)Butanoic Acid / Sitagliptin Intermediate
- Parecoxib SodiuM API
- (3R)-3-{[(tert-butoxy)carbonyl]amino}-4-(2,4,5-trifluorophenyl)butanoic acid
- N-Boc Sitagliptin Acid Impurity
- Sitagliptin EP Impurity 15
- (R)-3-(Tert-Butoxycarbonyl)-4-(2,4,5-Trifluorophenyl)Butanoic Acid
- (R)-N-Boc-3-AMino-4-(2,4,5-trifluorophenyl)butanoic 
- Sitagliptin N-BOC Carboxylic Acid
- Sitagliptin Impurity 19
- Benzenebutanoicacid,b-[[(1,1-diMethylethoxy)carbonyl]aMino]-2,4,5-trifluoro-,(bR)-
- (3R)-N-(TERT-BUTOXYCARBONYL)-3-AMINO-4-(2,4,5-TRIFLUOROPHENYL)BU
- [[(1,1-dimethylethoxy)carbonyl]amino]-2,4,5-trifluoro-(R)-be...
- Sitagliptin Intermediate 1
- Sitagliptin interMediateB
- Boc-(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic acid (3R)-N-(tert-Butoxycarbonyl)-3-amino-4-(2,4,5-trifluorophenyl)butanoic acid
- Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-ButyricAci
- (βR)-β-[[(1,1-Dimethylethoxy)carbonyl]amino]-2,4,5-trifluorobenzenebutanoic acid
- [[(1,1-diMethylethoxy)carbonyl]aMino]-2,4,5-trifluoro-(R)-benzenebuta
- Sitagliptin Acid Boc Impurity (Impurity A)
- BOC-(R-)3-Amino-4(2,4,5-triflurophenyl)Butanoic acid
- BOC-(R)-3-AMINO-4-(2,4,5-TRIFLUORO-PHENYL)-BUTYRIC ACID ISO 9001：2015 REACH
- (3R)-N-(tert-Butoxycarbonyl)-3-amino-4-(2,4,5-trifluoro phenyl)butanoic acid [Sita Acid]
- butanoic acid (BOC acid)
- (R)-Boc-3-Amino-4-(2,4,5-trifluorophenyl)butanoicacid
- Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acid (Boc acid)
- (3R)-N-(tert-Butoxycarbonyl)-3-aMino-4-(2,4,5-trifluorophenyl)-butanoic acid- Boc-(R)-3-AMino-4-(2,4,5-trifluorophenyl)
- Benzenebutanoic acid, β-[[(1,1-dimethylethoxy)carbonyl]amino]-2,4,5-trifluoro-, (βR)-
- Sitagliptin Impurity 78
- BOC-(R)-3-AMINO-4-(2
- (R)-Sitagliptin N-Boc-Acid IMpurity
- [[(1,1-dimethylethoxy)carbonyl]amino]-2,4,5-trifluoro-(R)-benzenebutanoic acid
- (3R)-3-((1,1-DIMETHYLETHOXYCARBONYL)AMINO)-4-(2,4,5-TRIFLUROPHENYL)-BUTANOIC ACID
- 4-(6-{[(tert-butoxy)carbonyl]aMino}-1,2,5-trifluorocyclohexa-2,4-dien-1-yl)butanoic acid
- Boc-(R)-3-Amino-4-(2,4,5-trifluorphenyl)butanoic acid
- SITAGLIPTIN CAS 654671-78-0 INTERMEDIATES
- BOC- Butanoic Acid
- Sitagliptin N-BOC Carboxylic acid Impurity
- (3R)-N-Boc-3-amino-4-(2,4,5-trifluorophenyl)butanoic acid
- Sitagliptin Imp-1(sitagliptin Impurity-A)
- Boc-(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic acid, >=99%
- BOC-(R)-3-AMINO-4-(2,4,5-TRIFLUORO-PHENY
- Sitagliptin Impurity 19 ((R)-Sitagliptin N-Boc-Acid Impurity)
- (R)-3-(Boc-aMino)-4-(2,4,5-trifluorophenyl)butanoic acid
- (3R) - N - (tert butoxycarbonyl) -3-amino-4- (2,4,5-trifluorophenyl) butyric acid
- Vedi altri sinonimi
Ordinare per
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8 prodotti.
(3R)-3-[(1,1-dimethylethoxycarbonyl)amino]-4-(2,4,5-trifluorophenyl)butanoic acid
CAS:Formula:C15H18F3NO4Purezza:97%Colore e forma:SolidPeso molecolare:333.3029Sitagliptin Impurity 19 ((R)-Sitagliptin N-Boc-Acid Impurity)
CAS:Formula:C15H18F3NO4Colore e forma:White To Off-White SolidPeso molecolare:333.31(3R)-3-[(1,1-Dimethylethoxycarbonyl)amino]-4-(2,4,5-trifluorophenyl)butanoic acid
CAS:(3R)-3-[(1,1-Dimethylethoxycarbonyl)amino]-4-(2,4,5-trifluorophenyl)butanoic acidPurezza:98%Peso molecolare:333.306g/mol(R)-3-((tert-Butoxycarbonyl)amino)-4-(2,4,5-trifluorophenyl)butanoic Acid
CAS:Prodotto controllato<p>Applications (R)-3-((tert-Butoxycarbonyl)amino)-4-(2,4,5-trifluorophenyl)butanoic Acid has been used as a reactant for the preparation of dipeptidyl peptidase-4 (DPP4) inhibitors for the treatment of type 2 diabetes, such as sitagliptin.<br>References Kim, H.J., et. al.: Bioorg. Med. Chem. Lett., 22, 5545 (2012)<br></p>Formula:C15H18F3NO4Colore e forma:NeatPeso molecolare:333.30Ref: ST-EA-CP-S3014
10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiesta(R)-N-Boc-3-Amino-4-(2,4,5-trifluorophenyl)butanoic acid
CAS:Formula:C15H18F3NO4Purezza:95%Colore e forma:SolidPeso molecolare:333.307Boc-(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic acid
CAS:<p>Intermediate in the synthesis of sitagliptin</p>Formula:C15H18F3NO4Purezza:Min. 95%Peso molecolare:333.3 g/mol
![(3R)-3-[(1,1-dimethylethoxycarbonyl)amino]-4-(2,4,5-trifluorophenyl)butanoic acid](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA0038OZ.jpg&w=3840&q=75)
![(3R)-3-[(1,1-Dimethylethoxycarbonyl)amino]-4-(2,4,5-trifluorophenyl)butanoic acid](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F54%2Fthumb%2FPC99712.jpg&w=3840&q=75)
