CAS 495-85-2

(+)-Methysticin

Descrizione:

(+)-Methysticin è un composto che si trova naturalmente classificato come un flavonoide, specificamente un derivato della metisticina, trovato principalmente nella specie vegetale *Piper methysticum*, comunemente conosciuta come kava. Questo composto è noto per le sue proprietà psicoattive ed è stato tradizionalmente utilizzato in varie culture per i suoi effetti calmanti e ansiolitici. Chimicamente, presenta una struttura complessa che include uno scheletro di cromona, contribuendo alla sua attività biologica. (+)-Methysticin mostra proprietà antiossidanti ed è stato studiato per i suoi potenziali effetti terapeutici, comprese le attività anti-infiammatorie e neuroprotettive. Il composto è tipicamente caratterizzato dalla sua solubilità in solventi organici e dalla limitata solubilità in acqua. Il suo profilo farmacologico suggerisce che potrebbe interagire con i sistemi di neurotrasmettitori, sebbene siano necessarie ulteriori ricerche per chiarire completamente i suoi meccanismi d'azione e i potenziali benefici per la salute. Come molti prodotti naturali, la sicurezza e l'efficacia di (+)-Methysticin nelle applicazioni terapeutiche richiedono un'attenta considerazione e ulteriori indagini.

Formula: C₁₅H₁₄O₅

InChI: InChI=1S/C15H14O5/c1-17-12-7-11(20-15(16)8-12)4-2-10-3-5-13-14(6-10)19-9-18-13/h2-6,8,11H,7,9H2,1H3/b4-2+/t11-/m0/s1

InChI key: InChIKey=GTEXBOVBADJOQH-FWEMWIAWSA-N

SMILES: C(=C/[C@H]1CC(OC)=CC(=O)O1)\C=2C=C3C(=CC2)OCO3

Sinonimi:

• (+)-Methysticin
• (6R)-6-[(1E)-2-(1,3-Benzodioxol-5-yl)ethenyl]-5,6-dihydro-4-methoxy-2H-pyran-2-one
• (6R)-6-[(E)-2-(1,3-benzodioxol-5-yl)ethenyl]-4-methoxy-5,6-dihydro-2H-pyran-2-one
• (6R)-6-[(E)-2-(1,3-benzodioxol-5-yl)vinyl]-4-methoxy-5,6-dihydro-2H-pyran-2-one
• 2H-Pyran-2-one, 5,6-dihydro-4-methoxy-6-[3,4-(methylenedioxy)styryl]-, (R)-
• 2H-Pyran-2-one, 6-[(1E)-2-(1,3-benzodioxol-5-yl)ethenyl]-5,6-dihydro-4-methoxy-, (6R)-
• 2H-Pyran-2-one, 6-[2-(1,3-benzodioxol-5-yl)ethenyl]-5,6-dihydro-4-methoxy-, [R-(E)]-
• 2H-pyran-2-one, 6-[(E)-2-(1,3-benzodioxol-5-yl)ethenyl]-5,6-dihydro-4-methoxy-, (6R)-
• 4-Methoxy-6-[b-(3',4'-methylenedioxyphenyl)vinyl]-5,6-dihydro-a-pyrone
• 5-Hydroxy-3-methoxy-7-[3,4-(methylenedioxy)phenyl]-2,6-heptadienoic Acid d-Lactone
• 6-(3',4'-Methylenedioxystyryl)-4-methoxy-5,6-dihydro-2H-pyran-2-one
• Kavahin
• Kavatin
• Methylsticin
• NSC 112158
• [R-(E)]-6-[2-(1,3-Benzodioxol-5-yl)ethenyl]-5,6-dihydro-4-methoxy-2H-pyran-2-one

Methylsticin

CAS: 495-85-2

Formula: C₁₅H₁₄O₅

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 274.2687

Ref: IN-DA00DA4R

Methylsticin

CAS: 495-85-2

Methylsticin

Purezza: ≥98%

Peso molecolare: 274.27g/mol

Ref: 54-BUP03119

Methysticin

CAS: 495-85-2

Formula: C₁₅H₁₄O₅

Peso molecolare: 274.27

Ref: 7W-GY0145

Methysticin

CAS: 495-85-2

Formula: C₁₅H₁₄O₅

Purezza: 95%~99%

Peso molecolare: 274.272

Ref: BP-BP0945

Methysticin

CAS: 495-85-2

Formula: C₁₅H₁₄O₅

Peso molecolare: 274.27

Ref: 4Z-M-236002

Methylsticin

CAS: 495-85-2

Methysticin, a kavalactone from kava roots, inhibits osteoclasts, NF-χB, stimulates Nrf2, reduces Na+ channel peaks, and hinders fungal growth.

Formula: C₁₅H₁₄O₅

Purezza: 99.27% - 99.37%

Colore e forma: White Powder

Peso molecolare: 274.27

Ref: TM-TN2347

Methysticin

CAS: 495-85-2

Lactone

Formula: C₁₅H₁₄O₅

Purezza: ≥ 98.0 % (HPLC)

Colore e forma: Powder

Peso molecolare: 274.27

Ref: 5G-89250

Kavatin

Prodotto controllato

CAS: 495-85-2

Applications A lactone isolated from the Kava plant (Piper methysticum). The active constituents of Kava are a group of approx. 18 compounds collectively referred to as kavalactones or kava pyrones. One of the active components of the intoxicating beverage Kava from the Pacific Islands.
References Keledjian, J., et al.: J. Pharm. Sci., 77, 1003 (1988), Clouatre, D., et al.: Toxicol. Lett., 150, 85 (2004), Mathews, J., et al.: Drug Metab. Dispos., 33, 1555 (2005), Clayton, N., et al.: Exp. Toxicol. Pathol., 58, 223 (2007),

Formula: C₁₅H₁₄O₅

Colore e forma: Neat

Peso molecolare: 274.27

Ref: TR-K145500

Methysticin

CAS: 495-85-2

Methysticin is one of the major kavalactones found in the roots of the kava plant, which is scientifically known as *Piper methysticum*. This compound is derived from the rhizomes of the South Pacific plant, where it exists alongside other kavalactones that collectively contribute to the plant’s bioactive profile. Methysticin's primary mode of action is believed to involve modulation of neurotransmitter systems, particularly through interactions with GABAergic pathways, leading to its anxiolytic and sedative effects.

Formula: C₁₅H₁₄O₅

Purezza: Min. 98 Area-%

Colore e forma: White Powder

Peso molecolare: 274.27 g/mol

Ref: 3D-FM69761