CAS 49745-95-1

Cloridrato di dobutamina

Descrizione:

Cloridrato di dobutamina è una catecolamina sintetica e un potente agente inotropo utilizzato principalmente nel trattamento dell'insufficienza cardiaca e dello shock cardiogeno. Agisce principalmente sui recettori adrenergici beta-1, portando a un aumento della contrattilità miocardica e a un miglioramento della gittata cardiaca senza aumentare significativamente la frequenza cardiaca. La sostanza viene tipicamente somministrata per via endovenosa a causa del suo rapido inizio d'azione e della breve emivita. Cloridrato di dobutamina è una polvere cristallina bianca o bianco sporco che è solubile in acqua e ha un intervallo di pH che è generalmente neutro. La sua formula chimica è C18H23N3O3·HCl e ha un peso molecolare di circa 345,86 g/mol. Il composto è spesso utilizzato in contesti clinici per l'ecocardiografia da stress e per gestire pazienti con insufficienza cardiaca acuta. Come per qualsiasi farmaco, è essenziale monitorare i pazienti per potenziali effetti collaterali, inclusi aritmie e ipotensione, durante la sua somministrazione.

Formula: C₁₈H₂₃NO₃·ClH

InChI: InChI=1S/C18H23NO3.ClH/c1-13(2-3-14-4-7-16(20)8-5-14)19-11-10-15-6-9-17(21)18(22)12-15;/h4-9,12-13,19-22H,2-3,10-11H2,1H3;1H

InChI key: InChIKey=BQKADKWNRWCIJL-UHFFFAOYSA-N

SMILES: C(CNC(CCC1=CC=C(O)C=C1)C)C2=CC(O)=C(O)C=C2.Cl

Sinonimi:

• 1,2-Benzenediol, 4-[2-[[3-(4-hydroxyphenyl)-1-methylpropyl]amino]ethyl]-, hydrochloride
• 1,2-Benzenediol, 4-[2-[[3-(4-hydroxyphenyl)-1-methylpropyl]amino]ethyl]-, hydrochloride (1:1)
• 4-(2-{[4-(4-Hydroxyphenyl)Butan-2-Yl]Amino}Ethyl)Benzene-1,2-Diol Hydrochloride (1:1)
• <span class="text-smallcaps">DL</span>-Dobutamine hydrochloride
• Benzene-1,2-Diol Hydrochloride
• Dobutamine Hydrochloride
• Dobutrex
• Inotrex
• NSC 299583
• dl-Dobutamine hydrochloride

Dobutamine Hydrochloride

CAS: 34368-04-2, 49745-95-1

Formula: C₁₈H₂₃NO₃·HCl

Purezza: >98.0%(HPLC)

Colore e forma: White to Light yellow to Light orange powder to crystal

Peso molecolare: 337.84

Ref: 3B-D4335

Dobutamine hydrochloride

CAS: 49745-95-1

Dobutamine hydrochloride is a catecholamine that acts as a -adrenergic receptor agonist. It has its strongest effects on 1 receptors, with lesser but significant 2 receptor activation and only weak 1 receptor actions. As a result, it strongly increases cardiac contractility with modest chronotropic,

Formula: C₁₈H₂₄ClNO₃

Colore e forma: Powder, White to off-white

Peso molecolare: 337.84

Ref: 02-J61333

Dobutamine hydrochloride

CAS: 49745-95-1

Dobutamine hydrochloride

Formula: C₁₈H₂₃NO₃ / C₁₈H₂₃NO₃HCl

Purezza: 89.1% / 99.9%

Colore e forma: Off-White

Peso molecolare: 301.16779

Ref: 47-674

DOBUTAMINE HYDROCHLORIDE CRS

CAS: 49745-95-1

DOBUTAMINE HYDROCHLORIDE CRS

Ref: 41-D2954000

Dobutamine Hydrochloride

CAS: 49745-95-1

Amino-naphthols and other amino-phenols, their ethers and esters, other than those cont more than one kind of oxygen function; salts thereof nesoi

Formula: C₁₈H₂₃NO₃·HCl

Colore e forma: White Off-White Crystalline Powder

Peso molecolare: 337.14447

Ref: 45-1224507

Dobutamine Hydrochloride

CAS: 49745-95-1

Dobutamine Hydrochloride

Purezza: 98%

Peso molecolare: 337.84g/mol

Ref: 54-OR1024667

Dobutamine hydrochloride

CAS: 49745-95-1

Dobutamine hydrochloride

Purezza: ≥95%

Peso molecolare: 337.84g/mol

Ref: 54-BUP11279

Dobutamine hydrochloride

CAS: 49745-95-1

Formula: C₁₈H₂₃NO₃HCl

Peso molecolare: 337.85

Ref: 7W-GP1178

Dobutamine Hydrochloride

Prodotto controllato

CAS: 49745-95-1

Formula: C₁₈H₂₃NO₃·ClH

Colore e forma: Neat

Peso molecolare: 337.84

Ref: 86-MM0675.00

Dobutamine hydrochloride

CAS: 49745-95-1

Formula: C₁₈H₂₄ClNO₃

Purezza: 95%~99%

Peso molecolare: 337.844

Ref: BP-BP4215

Dobutamine hydrochloride

CAS: 49745-95-1

Dobutamine hydrochloride (Dobutamine (hydrochloride)) is a catecholamine that acts as a β-adrenergic receptor agonist with potent positive inotropic effects.

Formula: C₁₈H₂₄ClNO₃

Purezza: 97.15% - 99.94%

Colore e forma: Solid

Peso molecolare: 337.84

Ref: TM-T8149

Dobutamine Hydrochloride RS

CAS: 49745-95-1

Colore e forma: White To Very Pale Orange

Ref: 2K-1091000021

rac Dobutamine Hydrochloride

CAS: 49745-95-1

Stability Hygroscopic
Applications A sympathomimetic drug used to treat heart failure by inhibiting β1 receptors in the sympathetic nervous system. Cardiotonic.
References Marrero-Ponce, Y., et al.: Bioorg. Med. Chem., 13, 2881 (2005), Abdel F., et al.: J. Drug Res., 29, 83 (2008), Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010),

Formula: C₁₈H₂₃NO₃·ClH

Colore e forma: Off-White

Peso molecolare: 337.84

Ref: TR-D494445

Dobutamine Hydrochloride

CAS: 49745-95-1

Formula: C₁₈H₂₃NO₃HCl

Peso molecolare: 301.38 : 36.46

Ref: ST-EA-CP-D59000

4-[2-[[3-(4-Hydroxyphenyl)-1-methylpropyl]amino]ethyl]-1,2-benzenediol hydrochloride

CAS: 49745-95-1

Dobutamine is a beta-adrenergic agonist that causes the heart to contract and increase blood pressure. It is used for pharmacological treatment of congestive heart failure and ventricular arrhythmias, as well as during angiography of the coronary arteries. Dobutamine stimulates dopamine receptors in the heart, which increases the systolic pressure. Dobutamine has been shown to be effective in improving myocardial contractility, left ventricle function, and cardiac output in patients with chronic congestive heart failure. This drug also improves left ventricular regional wall motion, papillary muscle function, and mitral valve regurgitation. Dobutamine may cause side effects such as nausea, vomiting, headache, or chest pain.

Formula: C₁₈H₂₄ClNO₃

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 337.84 g/mol

Ref: 3D-FH27507

Dobutamine hydrochloride

CAS: 49745-95-1

Formula: C₁₈H₂₄ClNO₃

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 337.84

Ref: 10-F240166