CAS 50-55-5

(-)-Reserpina

Descrizione:

(-)-Reserpina è un alcaloide indolico derivato dalla pianta Rauwolfia serpentina, comunemente noto per il suo uso nella medicina tradizionale e come agente antipertensivo. È caratterizzato dalla sua struttura complessa, che include un nucleo tetraciclico e un gruppo metossilico. Il composto presenta un centro chirale, risultando nella sua designazione come "(-)-Reserpina," che indica la sua specifica forma enantiomerica. (-)-Reserpina funziona principalmente come antagonista delle monoamine, influenzando i livelli di neurotrasmettitori nel cervello, in particolare inibendo l'assorbimento di norepinefrina e serotonina. Questo meccanismo contribuisce ai suoi effetti sedativi e antipertensivi. La sostanza viene tipicamente somministrata nella sua forma salina, come cloridrato di reserpina, ed è nota per la sua emivita relativamente lunga. Oltre alle sue applicazioni terapeutiche, (-)-Reserpina è stato studiato per i suoi potenziali effetti sui disturbi della salute mentale, sebbene il suo uso sia diminuito a causa dello sviluppo di nuovi farmaci con meno effetti collaterali. Le considerazioni di sicurezza includono potenziali effetti avversi come sedazione, disturbi gastrointestinali e impatti cardiovascolari.

Formula: C₃₃H₄₀N₂O₉

InChI: InChI=1/C33H40N2O9/c1-38-19-7-8-20-21-9-10-35-16-18-13-27(44-32(36)17-11-25(39-2)30(41-4)26(12-17)40-3)31(42-5)28(33(37)43-6)22(18)15-24(35)29(21)34-23(20)14-19/h7-8,11-12,14,18,22,24,27-28,31,34H,9-10,13,15-16H2,1-6H3/p+1/t18-,22+,24-,27+,28+,31+/m1/s1

InChI key: InChIKey=QEVHRUUCFGRFIF-MDEJGZGSSA-N

SMILES: C(OC)(=O)[C@H]1[C@]2(C[C@@]3(C4=C(C=5C(N4)=CC(OC)=CC5)CCN3C[C@]2(C[C@@H](OC(=O)C6=CC(OC)=C(OC)C(OC)=C6)[C@@H]1OC)[H])[H])[H]

Sinonimi:

• (3Beta,16Beta,17Alpha,18Alpha,20Alpha)-11,17-Dimethoxy-16-(Methoxycarbonyl)-18-[(3,4,5-Trimethoxybenzoyl)Oxy]Yohimban-4-Ium
• (3Beta,16Beta,17Alpha,18Beta,20Alpha)-11,17-Dimethoxy-16-(Methoxycarbonyl)-18-[(3,4,5-Trimethoxybenzoyl)Oxy]Yohimban-4-Ium
• 11,17-Dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]yohimban-16-carboxylic acid methyl ester
• 3,4,5-Trimethoxybenzoyl methyl reserpate
• 3β,20α-Yohimban-16β-carboxylic acid, 18β-hydroxy-11,17α-dimethoxy- methyl ester 3,4,5-trimethoxybenzoate (ester)
• 3β,20α-Yohimban-16β-carboxylic acid, 18β-hydroxy-11,17α-dimethoxy-, methyl ester, 3,4,5-trimethoxybenzoate
• Anquil
• Apoplon
• Banasil
• Benz[g]indolo[2,3-a]quinolizine, yohimban-16-carboxylic acid deriv.
• Bioserpine
• Carpacil
• Crystoserpine
• Deserpine
• Elserpine
• Ent 50146
• Eserpine
• Eskaserp
• Hiposerpil
• Kitine
• Lemiserp
• Loweserp
• Mayserpine
• Methyl reserpate 3,4,5-trimethoxybenzoate (ester)
• Nsc 237659
• Nsc 59272
• Quiescin
• Rau-sed
• Raucap
• Raulen
• Raunervil
• Raupasil
• Raurine
• Rausedil
• Rausedyl
• Rausingle
• Rauwasedin
• Resercaps
• Resercen
• Reserlor
• Reserpamed
• Reserpex
• Reserpic acid methyl ester 3,4,5-trimethoxybenzoate (ester)
• Reserpil
• Reserpin
• Reserpina
• Reserpine Crystalline
• Reserpine base
• Reserpine,98%
• Reserpoid
• Resine
• Resperine
• Respital
• Restran
• Riserpa
• Rivasin
• Roxinoid
• Sandril
• Sedaraupin
• Sedserp
• Serfin
• Serolfia
• Serp-AFD
• Serpaloid
• Serpanray
• Serpasil
• Serpasil Serpasol
• Serpasil premix
• Serpasol
• Serpate
• Serpen
• Serpentina
• Serpicon
• Serpiloid
• Serpine
• Serpine (pharmaceutical)
• Serpipur
• Sertabs
• Sertina
• T-Serp
• Temposerpine
• Triserpin
• Vio-Serpine
• Yohimban-16-carboxylic acid, 11,17-dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]-, methyl ester, (3β,16β,17α,18β,20α)-
• NCI-C50157
• Anguil
• rauwita
• Ascoserpina
• imethoxy-,methylester,3,4,5-trimethoxybenzoate(ester)
• diutensen-r
• 3,20-YohiMban-16-carboxylic acid
• hydroserp
• gamma-Serpine
• serpasilpremix
• Carrserp
• reserpene
• Austrapine
• serpalan
• Rausan
• Helfoserpin
• rcrawastenumberu200
• Hypersine
• chloroserpin-250
• serpazol
• Reserpine (base and/or unspecified salts)
• demi-regroton
• Neoserp
• reser-ar
• Interpina
• RESERPINE(RG)
• YohiMban-16-carboxylicacid, 11,17-diMethoxy-18-[(3,4,5-triMethoxybenzoyl)oxy]-, Methyl ester, (3b,16b,17a,18b,20a)-
• (3β,16β,17α,18β,20α)-
• Purserpine
• Alserin
• 11,17-dimethoxy-18-((3,4,5-trimethoxybenzoyl)oxy)-yohimban-16-carboxylicaci
• Rautrin
• salutensin
• rolserp
• trichlortensin
• Escaspere
• Alkarau
• Rauserpin-Alk
• oxy-methylester3,4,5-trimethoxybenzoate(ester)
• hydromox-r
• residine
• RESERPINE,USP
• chloroserp-500
• serpyrit
• Raugal
• chloroserpine-500
• reserp
• RESERPINE
• Enipresser
• RESERPINE,REAGENT
• Reserpine (200 mg)
• 11,17-dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]-yohimban-16-carboxylicaci
• Raudixoid
• Yohimban-16-carboxylic acid, 11,17-dimethoxy-18-(3,4,5-trimethoxybenzoyl)oxy-, methyl ester, (3.beta.,16.beta.,17.alpha.,18.beta.,20.alpha.)-
• serpresan
• Rausedan
• serpone
• Reserpine Standard for LC-MS
• Benazyl
• rezide
• serpasil-apresoline
• reserpidefe
• component of Butiserpazide
• serathide
• METHYL RESERPATE 3,4,5-TRIMETHOXYBENZOIC ACID ESTER
• METHYL RESERPATE
• R-e-s
• rivased
• Methyl reserpate 3,4,5-trimethyloxybenzoic acid
• hydrosine25
• reserfia
• klimanosid
• resedril
• serplexk
• Rauserpine
• Maviserpin
• Rauloydin
• renese-r
• diupres250
• rese-lar
• Carditivo
• serpivite
• Eskaserpine
• serpogen
• reserutin
• hydroserpineplus
• Broserpine
• Rauvlid
• banisil
• l-Carpserp
• mallopress
• ReserpineC33H40N209
• Eberpine
• hydro-reserpine-25
• serfolia
• chloroserp-250
• Eberspine
• metatensin#2
• tri-hydroserpine
• methylreserpate3,4,5-trimethoxybenzoicacid
• serpazil
• hydrochloride#2
• hydrochloride#1
• hydro-fluserpine#1
• recipin
• salutensin-demi
• Rauwipur
• serpazide
• resersana
• regroton
• hydropres50
• salazide-demi
• component of Regroton
• Yohimban-16-carboxylic acid, 11,17-dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]-, methyl ester, (3beta,16beta,17alpha,18beta,20alpha)-
• component of Renese R
• Rauserpol
• ReserpinePuriss
• reserpanca
• Key-serpine
• Reserpine bp
• Reserpine Vetec(TM) reagent grade
• diurese-r
• diupres500
• ser-a-gen
• reserpal
• ent50146
• Raupoid
• Reserpine, froM Rauvolfia
• Raunorine
• resomine
• (3beta,16beta,17alpha,18beta,20alpha)-methyleste
• hydropine
• hydroserpine#1
• metatensin#4
• RESERPINE BP/USP
• ,methylester,(3beta,16beta,17alpha,18beta,20alpha)-
• hydro-reserpine-50
• Raudiford
• resperin
• Idsoserp
• Rawilid
• Hiserpia
• hiposepil
• YohiMban-16-carboxylic acid
• Neo-antitensol
• RESERPINE, CRYSTALLIZED
• usafcb-27
• serpatone
• serpedin
• hydropres25
• salupres
• Rauwilid
• resiatric
• Neoserfin
• esidrix#2
• Reserbal
• Mephaserpin
• Reserpine,99%
• Hypersil
• reserpur
• hydroserpalan
• H 520
• Resedrex
• resaltex
• resocalm
• rezerpin
• Raumorine
• gilucard
• seominal
• 3beta,20alpha-Yohimban-16beta-carboxylic acid, 18beta-hydroxy-11,17alpha-dimethoxy-methyl ester 3,4,5-trimethoxybenzoate (ester)
• serpoid
• RESERPINE extrapure
• Rauwoleaf
• Reserjen
• (3β,16β,17α,18β,20α)-11,17-Dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]yohimban-16-carboxylicacidmethylester

Reserpine

CAS: 50-55-5

Formula: C₃₃H₄₀N₂O₉

Purezza: >98.0%(T)(HPLC)

Colore e forma: White to Light yellow to Light orange powder to crystal

Peso molecolare: 608.69

Ref: 3B-R0007

Reserpine, 99%

CAS: 50-55-5

Inhibits vesicular uptake of catecholamines and serotoninReserpine is an antipsychotic and antihypertensive drug used to treat the hypertension, strokes, heart attacks and kidney problems. It is used to treat the symptoms of dyskinesia in patients who are affected by huntington’s disease. It is wide

Formula: C₃₃H₄₀N₂O₉

Purezza: 99%

Colore e forma: White to cream to yellow, Powder

Peso molecolare: 608.69

Ref: 02-L03506

Reserpine

CAS: 50-55-5

Colore e forma: Neat

Ref: 61-FOR1423.00

RESERPINE CRS

CAS: 50-55-5

RESERPINE CRS

Formula: C₃₃H₄₀N₂O₉

Colore e forma: Crystalline Powder. White. Light Yellow. Small. Crystals. Powder.

Peso molecolare: 608.6787

Ref: 41-R0200000

Reserpine

CAS: 50-55-5

Vegetable alkaloids, natural or reproduced by synthesis, their salts and other derivatives, nesoi

Formula: C₃₃H₄₀N₂O₉

Colore e forma: White Pale Yellow Crystalline Powder

Peso molecolare: 608.27338

Ref: 45-1601000

Yohimban-16-carboxylic acid,11,17-dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]-, methyl ester,(3b,16b,17a,18b,20a)-

CAS: 50-55-5

Formula: C₃₃H₄₀N₂O₉

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 608.6787

Ref: IN-DA00ILKE

Reserpine

CAS: 50-55-5

Reserpine, an alkaloid from Rauwolfia roots, depletes neurotransmitters, used in treating hypertension and psychosis, but side effects restrict use.

Formula: C₃₃H₄₀N₂O₉

Purezza: 98.85% - 99.81%

Colore e forma: White Or Pale Buff To Slightly Yellowish Powder With A Bitter Taste (Ntp 1992)

Peso molecolare: 608.68

Ref: TM-T0791

Reserpine

CAS: 50-55-5

Reserpine

Purezza: 98%

Peso molecolare: 608.68g/mol

Ref: 54-OR1030229

Reserpine

CAS: 50-55-5

Formula: C₃₃H₄₀N₂O₉

Purezza: ≥ 98.0%

Colore e forma: White to pale yellow or faint brown powder

Peso molecolare: 608.69

Ref: 7W-GP9098

Reserpine

CAS: 50-55-5

Reserpine

Purezza: ≥98%

Peso molecolare: 608.68g/mol

Ref: 54-BUP14755

Reserpine

CAS: 50-55-5

Formula: C₃₃H₄₀N₂O₉

Colore e forma: Off-White Solid

Peso molecolare: 608.69

Ref: 4Z-R-123001

Reserpine

CAS: 50-55-5

Formula: C₃₃H₄₀N₂O₉

Purezza: 95%~99%

Peso molecolare: 608.688

Ref: BP-BP1203

Reserpine

Prodotto controllato

CAS: 50-55-5

Formula: C₃₃H₄₀N₂O₉

Colore e forma: Neat

Peso molecolare: 608.68

Ref: 04-C16809500

Reserpine

Prodotto controllato

CAS: 50-55-5

Formula: C₃₃H₄₀N₂O₉

Colore e forma: Neat

Peso molecolare: 608.68

Ref: 86-MM1423.00

Reserpine RS

CAS: 50-55-5

Colore e forma: White To Pale Yellow

Ref: 2K-1184000021

Reserpine

CAS: 50-55-5

Natural alkaloid

Formula: C₃₃H₄₀N₂O₉

Purezza: ≥ 95.0 % (HPLC)

Colore e forma: Powder

Peso molecolare: 608.69

Ref: 5G-82642

Reserpine

Prodotto controllato

CAS: 50-55-5

Applications An indole alkaloid found in Rauwolfia serpentina. Inhibits vesicular uptake of catecholamines and serotonin. Reserpine is reasonably anticipated to be a human carcinogen. Antihypertensive.
References Muller, J.M., et al.: Experientia, 8, 338 (1952), Schirmer, R.E., et al.: Anal. Profiles Drug Subs., 4, 384 (1975), Diener, R.M., et al.: Toxicol. Pathol., 8, 1 (1980),

Formula: C₃₃H₄₀N₂O₉

Colore e forma: Off-White

Peso molecolare: 608.68

Ref: TR-R144600

Reserpine - Bio-X ™

CAS: 50-55-5

Reserpine is an indole alkaloid that is found in the roots of the Rauwolfia plant. Reserpine has been shown to possess analgesic, anti-inflammatory, sedative, and anti-hypertensive properties. It is mainly used to treat mild to moderate hypertension. Reserpine inhibits the uptake of norepinephrine into storage vesicles by irreversibly blocking the vesicular monoamine transporter thus resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It is used as a pharmacological tool in research on chronic liver diseases.

Formula: C₃₃H₄₀N₂O₉

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 608.68 g/mol

Ref: 3D-BR164333

Reserpine

CAS: 50-55-5

VMAT monoamine transporter inhibitor; anti-hypertensive; anti-psychotic

Formula: C₃₃H₄₀N₂O₉

Purezza: Min. 95%

Colore e forma: White Powder

Peso molecolare: 608.68 g/mol

Ref: 3D-FR09862

Reserpine extrapure, 99%

CAS: 50-55-5

Formula: C₃₃H₄₀N₂O₉

Purezza: min. 99%

Colore e forma: White to pale yellow to pale beige to pale brown, Crystalline powder, Clear

Peso molecolare: 608.69

Ref: SR-46861