CAS 50-91-9
:Floxuridina
Descrizione:
Floxuridina, con il numero CAS 50-91-9, è un antimetabolita sintetico e un analogo fluorurato dell'uridina. È utilizzato principalmente nel trattamento di alcuni tipi di cancro, in particolare il cancro colorettale e le metastasi epatiche. Il composto agisce inibendo la sintesi del DNA, interferendo così con la proliferazione delle cellule tumorali. Floxuridina viene tipicamente somministrato tramite iniezione endovenosa o infusione intra-arteriosa, consentendo una somministrazione mirata ai siti tumorali. La sua struttura chimica include un atomo di fluoro, che migliora la sua attività antitumorale rispetto ai suoi omologhi non fluorurati. La sostanza è nota per i suoi potenziali effetti collaterali, che possono includere mielosoppressione, disturbi gastrointestinali e mucosite. A causa dei suoi effetti potenti e dell'applicazione specifica in oncologia, Floxuridina è classificato come un agente citotossico e viene maneggiato con cura in contesti clinici. Come per molti agenti chemioterapici, il monitoraggio delle reazioni avverse è essenziale durante il trattamento.
Formula:C9H11FN2O5
InChI:InChI=1/C9H11FN2O5/c10-4-2-12(9(16)11-8(4)15)7-1-5(14)6(3-13)17-7/h2,5-7,13-14H,1,3H2,(H,11,15,16)/t5-,6-,7?/m1/s1
InChI key:InChIKey=ODKNJVUHOIMIIZ-RRKCRQDMSA-N
SMILES:O=C1N([C@@H]2O[C@H](CO)[C@@H](O)C2)C=C(F)C(=O)N1
Sinonimi:- (+)-5-Fluorodeoxyuridine
- 1-(2-Deoxy-β-<span class="text-smallcaps">D</span>-ribofuranosyl)-5-fluorouracil
- 1-(2-Deoxy-β-D-ribofuranosyl)-5-fluorouracil
- 1-(2-deoxy-D-threo-pentofuranosyl)-5-fluoropyrimidine-2,4(1H,3H)-dione
- 1-(2-deoxypentofuranosyl)-5-fluoropyrimidine-2,4(1H,3H)-dione
- 2-Deoxy-5-fluorouridine
- 5-Fluoro-2'-deoxy-β-uridine
- 5-Fluoro-2?Deoxy Uridine
- 5-Fluorouracil 2'-deoxyriboside
- 5-Fluorouracil deoxyriboside
- 5-Fudr
- Deoxyfluorouridine
- FdUrd
- Floxiridina
- Floxuridin
- Floxuridine
- Fudr
- Nsc 26740
- Nsc 27640
- Uridine, 2'-deoxy-5-fluoro-
- 5-Fluoro-2′-deoxyuridine
- 5-Fluoro-2'-deoxyuridine
- 5-Fluoro-2-deoxyuridine
- (+)-5-Fluoro-2?deoxyuridine
- 5-FDU
- 5-FLOXURIDINE
- 2’-deoxy-5-fluoro-uridin
- 1-beta-d-2’-deoxyribofuranosyl-5-flurouracil
- 1beta-D-2'-Deoxyribofuranosyl-5-fluorouracil
- 5-FLUORO-2'-DEOXY-BETA-URIDINE
- 5-FLUORO-1-((2R,4S,5R)-4-HYDROXY-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-2-YL)-1H-PYRIMIDINE-2,4-DIONE
- fluorodeoxyuridine
- 1-(2-DEOXY-BETA-D-RIBOFURANOSYL)-5-FLUOROURACIL
- Vedi altri sinonimi
Ordinare per
Purezza (%)
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14 prodotti.
2'-Deoxy-5-fluorouridine
CAS:Formula:C9H11FN2O5Purezza:>98.0%(T)(HPLC)Colore e forma:White to Almost white powder to crystalPeso molecolare:246.195-Fluoro-2'-deoxyuridine, 98+%
CAS:<p>5-Fluoro-2'-deoxyuridine acts as an antiviral and antineoplastic agent. It is also employed for renal function diagnosis. Further, it is used as an experimental anticancer agent, which shows activity against a variety of malignant neoplasms. It is also used as an inhibitor of thymidylate synthetase </p>Formula:C9H11FN2O5Purezza:98+%Colore e forma:White to pale cream, PowderPeso molecolare:246.19Floxuridine
CAS:Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFormula:C9H11FN2O5Colore e forma:White Off-White PowderPeso molecolare:246.195-fluoro-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione
CAS:Formula:C9H11FN2O5Purezza:98%Colore e forma:SolidPeso molecolare:246.1924Floxuridine
CAS:Floxuridine (FUDR) is an antimetabolite, floxuridine inhibits thymidylate synthase, resulting in disruption of DNA synthesis and cytotoxicity.Formula:C9H11FN2O5Purezza:98.92% - 99.96%Colore e forma:SolidPeso molecolare:246.195-Fluoro-2'-deoxyuridine
CAS:5-Fluoro-2'-deoxyuridineFormula:C9H11FN2O5Purezza:99%Colore e forma: white to off white solidPeso molecolare:246.19g/molRef: 4Z-F-083001
5mgPrezzo su richiesta10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaFloxuridine
CAS:Formula:C9H11FN2O5Purezza:(HPLC) ≥ 98.0%Colore e forma:White to off-white powderPeso molecolare:246.20Floxuridine
CAS:Prodotto controllato<p>Applications Floxuridine is an antiviral; antineoplastic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Harris, M., et al.: Biophys. J., 4, 203 (1964),<br></p>Formula:C9H11FN2O5Colore e forma:NeatPeso molecolare:246.19Floxuridine-13C,15N2
CAS:Prodotto controllato<p>Applications Labelled Floxuridine. Antiviral; antineoplastic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Harris, M., et al.: Biophys. J., 4, 203 (1964),<br></p>Formula:C813CH11F15N2O5Colore e forma:WhitePeso molecolare:249.172'-Deoxy-5-fluorouridine
CAS:<p>2'-Deoxy-5-fluorouridine is a nucleoside analog that inhibits the enzyme ribonucleotide reductase, which is involved in the synthesis of DNA. It has been shown to inhibit the growth of cancer cells and induce apoptosis in vivo. 2'-Deoxy-5-fluorouridine has also been shown to inhibit tumor growth in animal models by inhibiting the production of reactive oxygen species and upregulating tumor suppressor genes, such as p53. This drug also has inhibitory effects on enzymes that are involved in cell proliferation, such as protein kinase C and tyrosine kinases. 2'-Deoxy-5-fluorouridine is metabolized by water vapor, so it must be administered with a humidifier or nebulizer. 2'-Deoxy-5-fluorouridine may cause side effects such as nausea, vomiting, and diarrhea.</p>Formula:C9H11FN2O5Purezza:Min. 98 Area-%Colore e forma:White Off-White PowderPeso molecolare:246.2 g/mol2′-Deoxy-5-fluorouridine
CAS:Formula:C9H11FN2O5Purezza:98%Colore e forma:White powderPeso molecolare:246.1945-Fluoro-2-Deoxyuridine extrapure, 98%
CAS:Formula:C9H11FN2O5Purezza:min. 98%Colore e forma:White to off white, Crystalline powderPeso molecolare:246.20
![5-fluoro-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-di…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA0035VM.jpg&w=3840&q=75)
