CAS 500-62-9

Yangonina

Descrizione:

Yangonina è un composto naturale classificato come un derivato del benzopirano, trovato principalmente nella specie vegetale *Piper methysticum*, comunemente conosciuta come kava. È riconosciuto per le sue proprietà psicoattive ed è stato studiato per i suoi potenziali effetti terapeutici, in particolare in relazione all'ansia e al sollievo dallo stress. Yangonina presenta una struttura chimica unica che contribuisce alla sua attività biologica, comprese le interazioni con il sistema endocannabinoide. Il composto è noto per la sua natura lipofila, che gli consente di attraversare facilmente le membrane biologiche. In termini di solubilità, Yangonina è generalmente solubile in solventi organici, ma ha una solubilità limitata in acqua. Il suo profilo farmacologico suggerisce che potrebbe influenzare i sistemi dei neurotrasmettitori, sebbene siano necessarie ulteriori ricerche per chiarire completamente i suoi meccanismi d'azione e i potenziali benefici per la salute. Come molti prodotti naturali, la sicurezza e l'efficacia di Yangonina nelle applicazioni cliniche richiedono un'attenta considerazione e ulteriori indagini.

Formula: C₁₅H₁₄O₄

InChI: InChI=1S/C15H14O4/c1-17-12-6-3-11(4-7-12)5-8-13-9-14(18-2)10-15(16)19-13/h3-10H,1-2H3/b8-5+

InChI key: InChIKey=XLHIYUYCSMZCCC-VMPITWQZSA-N

SMILES: C(=C/C1=CC=C(OC)C=C1)\C2=CC(OC)=CC(=O)O2

Sinonimi:

• (E)-4-Methoxy-6-[2-(4-methoxyphenyl)ethenyl]-2H-pyran-2-one
• 2H-Pyran-2-one, 4-methoxy-6-(p-methoxystyryl)-
• 2H-Pyran-2-one, 4-methoxy-6-[(1E)-2-(4-methoxyphenyl)ethenyl]-
• 2H-Pyran-2-one, 4-methoxy-6-[2-(4-methoxyphenyl)ethenyl]-, (E)-
• 2H-pyran-2-one, 4-methoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]-
• 4-Methoxy-6-[(1E)-2-(4-methoxyphenyl)ethenyl]-2H-pyran-2-one
• 4-Methoxy-6-[(E)-2-(4-methoxyphenyl)vinyl]-2H-pyran-2-on
• 4-Methoxy-6-[(E)-2-(4-methoxyphenyl)vinyl]-2H-pyran-2-one
• 4-Methoxy-6-[b-(p-anisyl)vinyl]-a-pyrone
• 4-Méthoxy-6-[(E)-2-(4-méthoxyphényl)éthènyl]-2H-pyran-2-one
• 5-Hydroxy-3-methoxy-7-(p-methoxyphenyl)-2,4,6-heptatrienoic Acid d-Lactone
• 6-(p-Methoxystyryl)-4-methoxy-a-pyrone

Yangonin

CAS: 500-62-9

Yangonin analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.

Formula: C₁₅H₁₄O₄

Purezza: (HPLC) ≥95%

Colore e forma: Powder

Peso molecolare: 258.27

Ref: 11-4989

Yangonin

CAS: 500-62-9

Formula: C₁₅H₁₄O₄

Peso molecolare: 258.27

Ref: 7W-GY4353

yangonin

CAS: 500-62-9

yangonin

Purezza: ≥98%

Peso molecolare: 258.27g/mol

Ref: 54-BUP05071

Yangonin

CAS: 500-62-9

Formula: C₁₅H₁₄O₄

Purezza: 95%~99%

Peso molecolare: 258.273

Ref: BP-BP1460

yangonin

CAS: 500-62-9

Yangonin (Y100550) is a novel CB1 receptor ligand with affinity for human recombinant CB1 receptors.

Formula: C₁₅H₁₄O₄

Purezza: 98.82% - 99.55%

Colore e forma: Pale Yellow Powder

Peso molecolare: 258.27

Ref: TM-T3S0738

Yangonin

CAS: 500-62-9

Formula: C₁₅H₁₄O₄

Peso molecolare: 258.27

Ref: 4Z-Y-007001

Yangonin

CAS: 500-62-9

Lactone

Formula: C₁₅H₁₄O₄

Purezza: ≥ 95.0 % (HPLC)

Colore e forma: Powder

Peso molecolare: 258.27

Ref: 5G-89293

Yangonin

Prodotto controllato

CAS: 500-62-9

Applications A lactone isolated from the Kava plant (Piper methysticum). The active constituents of Kava are a group of approx. 18 compounds collectively referred to as kavalactones or kava pyrones. Kawain, dihydrokawain, methysticin, dihydromethysticin, yangonin, and desmethoxyyangonin are the six major kavalactones. Kava beverages and other preparations are known to be anxiolytic and are used for anxiety disorders. Dietary supplements containing the root of the kava shrub have been implicated in several cases of liver toxicity in humans, including several who required liver transplants after using kava supplements.
References Keledjian, J., et al.: J. Pharm. Sci., 77, 1003 (1988), Clouatre, D., et al.: Toxicol. Lett., 150, 85 (2004), Mathews, J., et al.: Drug Metab. Dispos., 33, 1555 (2005), Clayton, N., et al.: Exp. Toxicol. Pathol., 58, 223 (2007),

Formula: C₁₅H₁₄O₄

Colore e forma: Neat

Peso molecolare: 258.27

Ref: TR-Y100550

Yangonin

CAS: 500-62-9

Yangonin is a kavalactone, which is a type of compound found in the roots of the Piper methysticum plant, commonly known as kava. This product is derived through the extraction of kavalactones from the kava root, a process that isolates its active psychoactive components. Yangonin is known for its interaction with the brain's neuroreceptor systems, particularly the cannabinoid CB1 receptors. This interaction may contribute to its psychoactive effects, influencing mood and perception.

Formula: C₁₅H₁₄O₄

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 258.27 g/mol

Ref: 3D-FY137901

Yangonin-d3

Prodotto controllato

CAS: 500-62-9

Applications Isotope labelled analog of Yangonin (Y100550), a lactone isolated from the Kava plant (Piper methysticum). The active constituents of Kava are a group of approx. 18 compounds collectively referred to as kavalactones or kava pyrones. Kawain, dihydrokawain, methysticin, dihydromethysticin, yangonin, and desmethoxyyangonin are the six major kavalactones. Kava beverages and other preparations are known to be anxiolytic and are used for anxiety disorders. Dietary supplements containing the root of the kava shrub have been implicated in several cases of liver toxicity in humans, including several who required liver transplants after using kava supplements.
References Keledjian, J., et al.: J. Pharm. Sci., 77, 1003 (1988), Clouatre, D., et al.: Toxicol. Lett., 150, 85 (2004), Mathews, J., et al.: Drug Metab. Dispos., 33, 1555 (2005), Clayton, N., et al.: Exp. Toxicol. Pathol., 58, 223 (2007),

Formula: C₁₅H₁₁D₃O₄

Colore e forma: Neat

Peso molecolare: 261.29

Ref: TR-Y100552