CAS 51481-61-9
:Cimetidina
Descrizione:
Cimetidina è un antagonista del recettore H2 dell'istamina utilizzato principalmente per ridurre la produzione di acido gastrico, risultando efficace nel trattamento di condizioni come ulcere peptiche, malattia da reflusso gastroesofageo (GERD) e sindrome di Zollinger-Ellison. La sua formula chimica è C10H13N5S e presenta un gruppo tiourea, fondamentale per la sua attività farmacologica. Cimetidina è noto per la sua capacità di inibire la secrezione di acido gastrico bloccando l'azione dell'istamina sui recettori H2 delle cellule parietali nel rivestimento dello stomaco. Inoltre, ha una emivita relativamente breve ed è metabolizzato nel fegato, con un certo potenziale di interazioni farmacologiche a causa del suo effetto sugli enzimi del citocromo P450. Gli effetti collaterali comuni possono includere vertigini, mal di testa e disturbi gastrointestinali. Cimetidina è anche noto per i suoi effetti antiandrogeni, che possono portare a ginecomastia in alcuni pazienti. Nel complesso, rimane un farmaco significativo nella gestione dei disturbi legati all'acido, sebbene agenti più recenti con meno effetti collaterali siano spesso preferiti nella pratica clinica.
Formula:C10H16N6S
InChI:InChI=1/C10H16N6S/c1-8-9(16-7-15-8)5-17-4-3-13-10(12-2)14-6-11/h7H,3-5H2,1-2H3,(H,15,16)(H2,12,13,14)
InChI key:InChIKey=AQIXAKUUQRKLND-UHFFFAOYSA-N
SMILES:C(SCCN=C(NC#N)NC)C1=C(C)N=CN1
Sinonimi:- 1-Cyano-2-methyl-3-[2-[(5-methyl-1H-imidazol-4-yl)methylsulfanyl]ethyl]guanidine
- 2-Cyano-1-Methyl-3-(2-(((5-Methylimidazol-4-Yl)Methyl)Thio)Ethyl)Guanidine
- Acibilin
- Acinil
- Biomet
- Cimal
- Cimetag
- Cimetidin
- Cimetidina
- Cimetidine (base or and unspecifieds salts)
- Cimetidine A
- Cimetidine AB
- Cimetum
- Dyspamet
- Edalene
- Eureceptor
- Fremet
- Gastromet
- Guanidine, N-cyano-N'-methyl-N''-[2-[[(5-methyl-1H-imidazol-4-yl)methyl]thio]ethyl]-
- Guanidine, N-cyano-N'-methyl-N''-[2-[[(4-methyl-1H-imidazol-5-yl)methyl]thio]ethyl]-
- Histodil
- N-Cyano-N'-methyl-N''-[2-((4-methyl-5-imidazolyl)-methylthio)ethyl]guanidine
- N-Cyano-N′′-methyl-N′-[2-[[(4-methyl-1H-imidazol-5-yl)methyl]thio]ethyl]guanidine
- Nsc 335308
- Peptol
- Skf 92334
- Tagamet
- Tagamet HB
- Tagamet HB 200
- Tamagret
- Tametin
- Tratul
- Ulcedin
- Ulcedine
- Ulcerex
- Ulcerfen
- Ulcimet
- Ulcofalk
- Ulcomedina
- Ulcomet
- Ulhys
- Cimetidine
- CIMETIDINE A TYPE
- FPF 1002
- N-CYANO-N'-METHYL-N''-[[2-[(5-METHYL-1H-IMIDAZOL-4-YL)METHYL]THIO]ETHYL]GUANIDINE
- CIMITIDINE
- ALTRAMET
- 2-CYANO-1-METHYL-3-[2-(5-METHYL-1H-IMIDAZOL-4-YL-METHYLTHIO)ETHYL]GUANIDINE
- Vedi altri sinonimi
Ordinare per
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22 prodotti.
Cimetidine
CAS:Formula:C10H16N6SPurezza:>99.0%(T)(HPLC)Colore e forma:White to Almost white powder to crystalPeso molecolare:252.34Cimetidine, 98+%
CAS:<p>Widely used H2 histamine antagonist which has more recently been described as an inverse agonist. Also a potent I1 imidazoline binding site ligand. It displays antitumor and immunomodulatory activity. Cimetidine competitively inhibits histamine binding to histamine H2 receptors, and suppresses the g</p>Formula:C10H16N6SPurezza:98+%Colore e forma:White to off-white, PowderPeso molecolare:252.34CIMETIDINE FOR PEAK IDENTIFICATION CRS
CAS:<p>CIMETIDINE FOR PEAK IDENTIFICATION CRS</p>Formula:C10H16N6SPeso molecolare:252.3392Cimetidine
CAS:CimetidineFormula:C10H16N6SPurezza:99.6%Colore e forma:White SolidPeso molecolare:252.11572Cimetidine
CAS:<p>Compounds containing an unfused imidazole ring, whether or not hydrogenated, in the structure, nesoi</p>Formula:C10H16N6SColore e forma:White Off-White Crystalline PowderPeso molecolare:252.11572(Z)-3-cyano-1-methyl-2-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl)guanidine
CAS:Formula:C10H16N6SPurezza:98%Colore e forma:SolidPeso molecolare:252.3392Cimetidine
CAS:<p>Cimetidine (SKF-92334) is a histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS.</p>Formula:C10H16N6SPurezza:99.82%Colore e forma:Crystals Physical Description White Crystals With A Slight Sulfur-Mercaptan Odor (Ntp 1992)Peso molecolare:252.34Cimetidine, USP grade
CAS:Formula:C10H16N6SPurezza:≤ 0.2%Colore e forma:White crystalline powderPeso molecolare:252.34Cimetidine
CAS:Formula:C10H16N6SPurezza:99.0 - 101.0 %Colore e forma:White to off-white powderPeso molecolare:252.34Cimetidine 100 µg/mL in Acetonitrile
CAS:Formula:C10H16N6SColore e forma:Single SolutionPeso molecolare:252.34Cimetidine
CAS:<p>Cimetidine is a histamine-2 receptor antagonist that inhibits gastric acid secretion and reduces the activity of stomach enzymes. It is used to treat peptic ulcers, gastroesophageal reflux disease, and Zollinger-Ellison syndrome. Cimetidine has been shown to inhibit the activity of drug-metabolizing enzymes such as cytochrome P450. Cimetidine also inhibits the transport protein P-glycoprotein (P-gp), which leads to increased concentrations of some drugs in the blood and tissues. This inhibition may lead to an increase in cardiac effects with certain drugs, such as x-ray diffraction data with taxol or h1 antagonists.</p>Formula:C10H16N6SPurezza:Min. 95%Colore e forma:White PowderPeso molecolare:252.34 g/molN-Cyano-N’-methyl-N”-[2-[[(4-methyl-1H-imidazol-5-yl)methyl]thio]ethyl]guanidine
CAS:Formula:C10H16N6SPurezza:98%Colore e forma:SolidPeso molecolare:252.34
![(Z)-3-cyano-1-methyl-2-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl)guanidine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA00I97O.jpg&w=3840&q=75)
![N-Cyano-N’-methyl-N”-[2-[[(4-methyl-1H-imidazol-5-yl)methyl]thio]ethyl]guanidine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb%2FF224139.jpg&w=3840&q=75)
