CAS 51798-45-9

Elastatinal

Descrizione:

Elastatinal è un composto chimico classificato come un peptide ciclico, specificamente un membro degli inibitori dell'elastasi. È derivato da fonti naturali, in particolare da alcune specie di funghi. Il composto mostra una notevole attività biologica, principalmente come inibitore dell'elastasi, un enzima che scompone l'elastina, una proteina chiave nei tessuti connettivi. Questa inibizione può avere implicazioni in vari processi fisiologici e potenziali applicazioni terapeutiche, in particolare in condizioni caratterizzate da un'eccessiva attività dell'elastasi, come la broncopneumopatia cronica ostruttiva (BPCO) e alcuni disturbi infiammatori. Elastatinal è caratterizzato dalla sua unica struttura ciclica, che contribuisce alla sua stabilità e specificità nel legarsi all'elastasi. Inoltre, è stato studiato per il suo potenziale ruolo nello sviluppo di farmaci grazie alla sua capacità di modulare l'attività proteolitica. Come molti composti bioattivi, sono necessarie ulteriori ricerche per comprendere appieno i suoi meccanismi d'azione, farmacocinetica e potenziali effetti collaterali in contesti clinici.

Formula: C₂₁H₃₆N₈O₇

InChI: InChI=1S/C21H36N8O7/c1-10(2)8-14(19(34)35)28-21(36)29-16(12-6-7-24-20(23)27-12)18(33)26-13(4-5-15(22)31)17(32)25-11(3)9-30/h9-14,16H,4-8H2,1-3H3,(H2,22,31)(H,25,32)(H,26,33)(H,34,35)(H3,23,24,27)(H2,28,29,36)/t11-,12-,13-,14-,16-/m0/s1

InChI key: InChIKey=IJWCGVPEDDQUDE-YGJAXBLXSA-N

SMILES: [C@H](C(N[C@H](C(N[C@H](C=O)C)=O)CCC(N)=O)=O)(NC(N[C@@H](CC(C)C)C(O)=O)=O)[C@]1(NC(N)=NCC1)[H]

Sinonimi:

• (2S)-2-[(4S)-2-Amino-3,4,5,6-tetrahydro-4-pyrimidinyl]-N-[[[(1S)-1-carboxy-3-methylbutyl]amino]carbonyl]glycyl-N¹-[(1S)-1-methyl-2-oxoethyl]-<span class="text-smallcaps">L</span>-glutamamide
• (2S,6S,9S,12S)-9-(3-amino-3-oxopropyl)-6-[(4S)-2-amino-3,4,5,6-tetrahydropyrimidin-4-yl]-12-methyl-2-(2-methylpropyl)-4,7,10,13-tetraoxo-3,5,8,11-tetraazatridecan-1-oic acid (non-preferred name)
• (2S,9S)-9-(3-amino-3-oxopropyl)-6-(2-amino-3,4,5,6-tetrahydropyrimidin-4-yl)-12-methyl-2-(2-methylpropyl)-4,7,10,13-tetraoxo-3,5,8,11-tetraazatridecan-1-oic acid (non-preferred name)
• 9-(3-Amino-3-Oxopropyl)-6-(2-Amino-3,4,5,6-Tetrahydropyrimidin-4-Yl)-12-Methyl-2-(2-Methylpropyl)-4,7,10,13-Tetraoxo-3,5,8,11-Tetraazatridecan-1-Oic Acid (Non-Preferred Name)
• <span class="text-smallcaps">L</smallcap>-Glutamamide, <smallcap>L</span>-2-(2-amino-1,4,5,6-tetrahydro-4-pyrimidinyl)-N-[[(1-carboxy-3-methylbutyl)amino]carbonyl]glycyl-N¹-(1-methyl-2-oxoethyl)-, stereoisomer
• <span class="text-smallcaps">L</span>-Glutamamide, (2S)-2-[(4S)-2-amino-1,4,5,6-tetrahydro-4-pyrimidinyl]-N-[[[(1S)-1-carboxy-3-methylbutyl]amino]carbonyl]glycyl-N¹-[(1S)-1-methyl-2-oxoethyl]-
• <span class="text-smallcaps">L</span>-Glutamamide, (2S)-2-[(4S)-2-amino-3,4,5,6-tetrahydro-4-pyrimidinyl]-N-[[[(1S)-1-carboxy-3-methylbutyl]amino]carbonyl]glycyl-N¹-[(1S)-1-methyl-2-oxoethyl]-
• Elastatinal
• N~2~-[(2S)-2-[(4S)-2-amino-3,4,5,6-tetrahydropyrimidin-4-yl]-2-({[(2S)-4-methyl-1-oxopentan-2-yl]carbamoyl}amino)acetyl]-N~1~-[(2S)-1-oxopropan-2-yl]-L-glutamamide
• L-Glutamamide, (2S)-2-[(4S)-2-amino-1,4,5,6-tetrahydro-4-pyrimidinyl]-N-[[[(1S)-1-carboxy-3-methylbutyl]amino]carbonyl]glycyl-N1-[(1S)-1-methyl-2-oxoethyl]-
• L-Glutamamide, (2S)-2-[(4S)-2-amino-3,4,5,6-tetrahydro-4-pyrimidinyl]-N-[[[(1S)-1-carboxy-3-methylbutyl]amino]carbonyl]glycyl-N1-[(1S)-1-methyl-2-oxoethyl]-
• L-Glutamamide, L-2-(2-amino-1,4,5,6-tetrahydro-4-pyrimidinyl)-N-[[(1-carboxy-3-methylbutyl)amino]carbonyl]glycyl-N1-(1-methyl-2-oxoethyl)-, stereoisomer

Elastatinal

CAS: 51798-45-9

Formula: C₂₁H₃₆N₈O₇

Purezza: 85%

Peso molecolare: 512.5599

Ref: IN-DA01E4MS

Elastatinal

CAS: 51798-45-9

Elastatinal is an elastase inhibitor. It is found in culture filtrates of various species of actinomyces.

Formula: C₂₁H₃₆N₈O₇

Colore e forma: Yellowish Solid

Peso molecolare: 512.56

Ref: TM-T20130

Elastatinal microbial

CAS: 51798-45-9

Formula: C₂₁H₃₆N₈O₇

Purezza: ~0.64μg/ml (IC50, pH8.8, 37°C)

Colore e forma: White to light-yellow or tan powder

Peso molecolare: 512.60

Ref: 7W-GL1320

Elastatinal

CAS: 51798-45-9

Elastatinal is a natural product that has been shown to inhibit the protease activity of HIV-1. This inhibition may be due to its ability to bind to the cell surface and prevent the assembly of the virus-cell complex. Elastatinal binds to hydroxyl groups on proteins, which may inhibit enzymes in cells by preventing them from carrying out their functions. The biological sample can be any type of biological fluid or tissue, such as blood, saliva, semen, and vaginal secretions. Elastatinal is a natural product that has been shown to inhibit the protease activity of HIV-1. This inhibition may be due to its ability to bind to the cell surface and prevent the assembly of the virus-cell complex. Elastatinal binds to hydroxyl groups on proteins, which may inhibit enzymes in cells by preventing them from carrying out their functions. The biological sample can be any type of biological fluid or tissue, such as blood, saliva, semen, and

Formula: C₂₁H₃₆N₈O₇

Purezza: Min. 95%

Peso molecolare: 512.56 g/mol

Ref: 3D-IEL-4064

Elastatinal

Prodotto controllato

CAS: 51798-45-9

Applications Elastatinal is an elastase inhibitor.

Formula: C₂₁H₃₆N₈O₇

Colore e forma: Neat

Peso molecolare: 512.56

Ref: TR-E501008

Elastatinal

CAS: 51798-45-9

Elastatinal is a research tool that is used to activate cells by binding to a receptor on the cell surface. Elastatinal belongs to the Ligand class of compounds and has been shown to bind to various ion channels and receptors, including cell surface receptors. This ligand binds with high affinity to the α-adrenergic receptor (α-AR) and activates cells that express this receptor. It also inhibits the binding of other ligands, such as bradykinin, which may be useful in pharmacology. Elastatinal is an inhibitor of protein interactions, which can be used in Cell Biology studies.

Formula: C₂₁H₃₆N₈O₇

Purezza: Min. 95%

Peso molecolare: 512.56 g/mol

Ref: 3D-IEL-4064-V

Elastatinal

CAS: 51798-45-9

Irreversible elastase inhibitor This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Formula: C₂₁H₃₆N₈O₇

Peso molecolare: 512.6

Ref: 02-J61120