CAS 519-37-9

Etofillina

Descrizione:

Etofillina, con il numero CAS 519-37-9, è un composto farmaceutico che appartiene alla classe dei derivati della xantina. È principalmente noto per le sue proprietà broncodilatatrici, rendendolo utile nel trattamento di condizioni respiratorie come asma e malattia polmonare ostruttiva cronica (BPCO). La sostanza è una combinazione di teofillina e alcol etilico, che ne migliora la solubilità e la biodisponibilità. Etofillina agisce rilassando i muscoli lisci delle vie aeree, facilitando così una respirazione più facile. Viene tipicamente somministrato in forme orali o iniettabili. Il composto presenta una emivita moderata e la sua farmacocinetica può essere influenzata da fattori come età, funzione epatica e farmaci concomitanti. Gli effetti collaterali possono includere disturbi gastrointestinali, nervosismo e insonnia, che sono comuni con i derivati della xantina. Grazie ai suoi effetti terapeutici e al profilo di sicurezza relativamente favorevole, Etofillina è utilizzato in contesti clinici, sebbene il suo uso possa essere limitato dalla disponibilità di nuovi broncodilatatori.

Formula: C₉H₁₂N₄O₃

InChI: InChI=1/C9H12N4O3/c1-11-7-6(8(15)12(2)9(11)16)13(3-4-14)5-10-7/h5,14H,3-4H2,1-2H3

InChI key: InChIKey=NWPRCRWQMGIBOT-UHFFFAOYSA-N

SMILES: C(CO)N1C2=C(N(C)C(=O)N(C)C2=O)N=C1

Sinonimi:

• 1,3-Dimethyl-7-(2-hydroxyethyl)xanthine
• 1H-Purine-2,6-dione, 3,7-dihydro-7-(2-hydroxyethyl)-1,3-dimethyl-
• 3,7-Dihydro-7-(2-hydroxyethyl)-1,3-dimethyl-1H-purine-2,6-dione
• 7-(2-Hydroxyethyl)-1,3-dimethylxanthine
• 7-(2-Hydroxyethyl)theophylline
• 7-(2-hydroxyethyl)-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione
• 7-(Hydroxyethyl)theophylline
• 7-(a-Hydroxyethyl)theophylline
• 7-(β-Hydroxyethyl)theophylline
• 7-Theophyllineethanol
• Aethophyllinum
• Ascorphylline
• Bio-phylline
• Cordalin
• Corophyllin-N
• Dilaphyllin
• Etofylline
• Etophyllin
• Etophylline
• Frekaphyllin
• Hydroxyethyltheophylline
• Kt 200G
• NSC 113373
• Oxphylline
• Oxyethophylline
• Oxyethyltheophylline
• Oxyphyllin
• Oxyphylline
• Oxytheonyl
• Phyllocormin N
• Soluphylline
• Theophylline, 7-(2-hydroxyethyl)-
• 7-(BETA-HYDROXYETHYL)THEOPHYLLINE
• BETA-HYDROXYETHYLTHEOPHYLLINE
• 7-(2-hydroxyethyl)-theophyllin
• b-hydroxyethyltheophylline
• 3,7-dihydro-7-(2-hydroxyethyl)-1,3-dimethyl-1h-purine-6-dione
• 1,3-DIMETHYL-7-(BETA-HYDROXYETHYL)XANTHINE
• BIOPHYLLINE

Etofylline

CAS: 519-37-9

Formula: C₉H₁₂N₄O₃

Purezza: >98.0%(HPLC)(N)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 224.22

Ref: 3B-H0402

Etofylline 1.0 mg/ml in Methanol

CAS: 519-37-9

Colore e forma: Single Solution

Ref: 61-AMP0603.00-01

Etofylline

CAS: 519-37-9

Colore e forma: Neat

Ref: 61-FOR0603.00

Theophylline USP Related Compound F

CAS: 519-37-9

Formula: C₉H₁₂N₄O₃

Peso molecolare: 224.2

Ref: ST-EA-CP-T59054

ETOFYLLINE CRS

CAS: 519-37-9

ETOFYLLINE CRS

Ref: 41-E2500000

Theophylline Related Compound F (7-(2-Hydroxyethyl)-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione)

CAS: 519-37-9

Theophylline and aminophylline (excluding fenetylline) and their derivatives, salts thereof, not elsewhere specified or included

Formula: C₉H₁₂N₄O₃

Colore e forma: White Powder

Peso molecolare: 224.09094

Ref: 45-1653060

Etofylline

CAS: 519-37-9

Formula: C₉H₁₂N₄O₃

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 224.2166

Ref: IN-DA003NC4

Etofylline

CAS: 519-37-9

Etofylline (Oxyphylline) is used for difficulty in breathing, asthma, breathing difficulty and other conditions.

Formula: C₉H₁₂N₄O₃

Purezza: 99.36%

Colore e forma: Solid

Peso molecolare: 224.22

Ref: TM-T0829

Etofylline

CAS: 519-37-9

Etofylline

Purezza: ≥98%

Peso molecolare: 224.22g/mol

Ref: 54-BUP18221

Etofylline

CAS: 519-37-9

Formula: C₉H₁₂N₄O₃

Peso molecolare: 224.22

Ref: 7W-GP6737

Theophylline EP Impurity F (Theophylline-Ethylenediamine EP Impurity F, Diprophylline EP Impurity C, Etofylline)

CAS: 519-37-9

Formula: C₉H₁₂N₄O₃

Colore e forma: White To Off-White Solid

Peso molecolare: 224.22

Ref: 4Z-T-603

Etofylline

CAS: 519-37-9

Colore e forma: Neat

Ref: 86-MM0603.00

7-(2-Hydroxyethyl)-1,3-dimethyl-1H-purine-2,6(3H,7H)-dione

CAS: 519-37-9

Formula: C₉H₁₂N₄O₃

Purezza: 95%

Colore e forma: Solid, White to almost white powder

Peso molecolare: 224.22

Ref: 10-F241302

Theophylline EP Impurity F-d6 (Theophylline-Ethylenediamine EP Impurity F-d6, Diprophylline EP Impurity C-d6, Etofylline-d6)

CAS: 519-37-9

Formula: C₉H₆D₆N₄O₃

Peso molecolare: 230.26

Ref: 4Z-T-6016

Etofylline

CAS: 519-37-9

Applications An inhibitor of 3’,5’-Cyclic Nucleotide Phosphodiesterase. Therapeutically, this compound has diuretic, muscle relaxant, bronchial dilation and CNS stimulant activities.
References Geraets, L., et al.: Biochem. Pharmacol., 72, 902 (2006), Kumar, A., et al.: J. Clin. Diagnostic Res., 2, 938 (2008), Tanno, F., et al.: J. Pharm. Sci., 97, 2665 (2008), Ma, C., et al.: J. Pharm. Biomed. Anal., 47, 677 (2008),

Formula: C₉H₁₂N₄O₃

Colore e forma: Neat

Peso molecolare: 224.22

Ref: TR-E933200

Etofylline

Prodotto controllato

CAS: 519-37-9

Etofylline is a potent antagonist of histamine receptors. It has been shown that etofylline binds to the H1 receptor and blocks the action of histamine on smooth muscle cells, leading to bronchodilation. Etofylline also has pharmacokinetic properties, including a rapid absorption in humans and high bioavailability. The drug is eliminated by hepatic metabolism with a half-life of about 7 hours. Etofylline is an analytical method for determining binding constants for hydrogen bonding interactions in biological systems such as proteins, nucleic acids, and carbohydrates. Toxicity studies show that etofylline can cause liver damage and respiratory problems in geriatric patients and pregnant women.

Formula: C₉H₁₂N₄O₃

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 224.22 g/mol

Ref: 3D-FE23197

Etofylline-D6

Prodotto controllato

CAS: 519-37-9

Formula: C₉H₆D₆N₄O₃

Colore e forma: Neat

Peso molecolare: 834.962

Ref: TR-E933202

Etofyllin

CAS: 519-37-9

Formula: C₉H₁₂N₄O₃

Peso molecolare: 224.22

Ref: ST-EA-CP-T59010

Diprophylline EP Impurity C

CAS: 519-37-9

Formula: C₉H₁₂N₄O₃

Peso molecolare: 224.2

Ref: ST-EA-CP-D166003