CAS 52-67-5

(-)-Penicillamina

Descrizione:

(-)-Penicillamina è un agente chelante e un derivato della penicillina, utilizzato principalmente nel trattamento di condizioni come l'artrite reumatoide e la malattia di Wilson, dove aiuta a rimuovere l'eccesso di rame dal corpo. È un amminoacido con un gruppo tiol, che gli consente di formare complessi con ioni metallici, migliorando i suoi effetti terapeutici. La sostanza è caratterizzata dalla sua natura chirale, esistendo come un singolo enantiomero, che è la forma biologicamente attiva. (-)-Penicillamina è tipicamente somministrato per via orale ed è noto per la sua capacità di legarsi ai metalli pesanti, facilitandone l'escrezione. Ha una solubilità relativamente bassa in acqua ed è sensibile alla luce e all'aria, richiedendo condizioni di stoccaggio adeguate. Gli effetti collaterali comuni possono includere disturbi gastrointestinali e reazioni cutanee, e il suo uso richiede monitoraggio a causa della potenziale tossicità e delle interazioni con altri farmaci. In generale, (-)-Penicillamina svolge un ruolo significativo nella gestione di specifiche condizioni mediche attraverso le sue uniche proprietà chimiche.

Formula: C₅H₁₁NO₂S

InChI: InChI=1/C5H11NO2S/c1-6(2)4(3-9)5(7)8/h4,9H,3H2,1-2H3,(H,7,8)

InChI key: InChIKey=VVNCNSJFMMFHPL-VKHMYHEASA-N

SMILES: [C@@H](C(C)(C)S)(C(O)=O)N

Sinonimi:

• (-)-Penicillamine
• (2S)-2-Azaniumyl-3-methyl-3-sulfanylbutanoate
• (2S)-2-amino-3-methyl-3-sulfanylbutanoic acid
• (S)-3,3-Dimethylcysteine
• (S)-Penicillamine
• 2-Amino-3-mercapto-3-methylbutanoic acid
• 3,3-Dimethyl-D-cysteine
• 3-Mercapto-<span class="text-smallcaps">D</span>-valine
• 3-Mercapto-D-valine
• <span class="text-smallcaps">D</span>-(-)-Penicillamine
• <span class="text-smallcaps">D</span>-3-Mercaptovaline
• <span class="text-smallcaps">D</span>-Mercaptovaline
• <span class="text-smallcaps">D</span>-Penamine
• <span class="text-smallcaps">D</span>-Valine, 3-mercapto-
• Artamin
• Cuprenil
• Cuprimine
• Cupripen
• D-3-Mercaptovaline
• D-Mercaptovaline
• D-Penamine
• D-Penicillin
• D-Valine, 3-mercapto-
• D-minus-penicillamine free base
• DPA
• Depamine
• Depen
• Dimethylcysteine
• H-D-Pen-OH
• Kuprenil
• Mercaptyl
• Metalcaptase
• N,N-dimethylcysteine
• Nsc 81549
• Pendramine
• Penicilamina
• Penicillamin
• Penicillamine, D-(-)-
• Penicilllamine
• Perdolat
• Reduced <span class="text-smallcaps">D</span>-penicillamine
• Reduced D-penicillamine
• Reduced penicillamine
• Sufirtan
• Trolovol
• Valine, 3-mercapto-, <span class="text-smallcaps">D</span>-
• Valine, 3-mercapto-, D-
• β-Thiovaline
• D-(-)-Penicillamine
• D-Penicillamine
• 3-mercapto-d-valin
• D(-)-2-AMINO-3-MERCAPTO-3-METHYLBUTANOIC ACID
• DISTAMINE
• (S)-2-AMINO-3-MERCAPTO-3-METHYL-BUTYRIC ACID
• alpha-amino-beta-methyl-beta-mercaptobutyricacid
• D-BETA,BETA-DIMETHYLCYSTEINE
• (S)-Penicillamin
• D[-]-2-AMINO-3-MERCAPTO-3-METHYLBUTANOIC ACID
• 3-Sulfanylvaline
• D-BETA-MERCAPTOVALINE

D-Penicillamine

CAS: 52-67-5

Formula: C₅H₁₁NO₂S

Purezza: >98.0%(T)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 149.21

Ref: 3B-P0147

D-(-)-Penicillamine, 98%

CAS: 52-67-5

It is used mainly as chelating agent in heavy metal poisoning as in lead, mercury and copper poisoning. It is used in Wilson's disease. It  is used in pharmacy as chelating agent and as immunosuppressant for treating rheumatoid arthritis by reducing the number of T cells, inhibiting the macrophages,

Formula: C₅H₁₁NO₂S

Purezza: 98%

Colore e forma: Powder, White to pale cream

Peso molecolare: 149.21

Ref: 02-A11446

PENICILLAMINE CRS

CAS: 52-67-5

PENICILLAMINE CRS

Formula: C₅H₇NO₃

Colore e forma: Powder

Peso molecolare: 129.114

Ref: 41-P0310000

Penicillamine

CAS: 52-67-5

Thioglycolic acid and mercaptocarboxylic acids

Formula: C₅H₁₁NO₂S

Colore e forma: White Off-White Powder

Peso molecolare: 149.21 g/mol

Ref: 45-1501006

Penicillamine

CAS: 52-67-5

Penicillamine (Artamine), possessing antineoplastic properties, induces apoptosis by a p53-mediated mechanism and inhibits angiogenesis by chelating with copper

Formula: C₅H₁₁NO₂S

Purezza: 99.69% - 99.8%

Colore e forma: Fine White Or Practically White Crystalline Powder Solid

Peso molecolare: 149.21

Ref: TM-T0983

D-Penicillamine

CAS: 52-67-5

Formula: C₅H₁₁NO₂S

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 149.2113

Ref: IN-DA0038OE

D-Penicillamine, Ph. Eur. grade

CAS: 52-67-5

Formula: C₅H₁₁NO₂S

Purezza: ≤ 0.1%

Colore e forma: White or almost white crystalline powder

Peso molecolare: 149.21

Ref: 7W-GA1554

Penicillamine

CAS: 52-67-5

Penicillamine

Purezza: ≥98%

Peso molecolare: 149.21g/mol

Ref: 54-BUP19801

D-Penicillamine

CAS: 52-67-5

Formula: C₅H₁₁NO₂S

Purezza: 98.0 - 101.0 % (dried basis)

Colore e forma: White to off-white powder

Peso molecolare: 149.21

Ref: 7W-GA2413

3-Thio-D-valine

CAS: 52-67-5

3-Thio-D-valine

Formula: C₅H₁₁NO₂S

Purezza: 98%

Colore e forma: white solid

Peso molecolare: 149.21g/mol

Ref: 54-OR18365

D-Penicillamine

CAS: 52-67-5

Formula: C₅H₁₁NO₂S

Peso molecolare: 149.21

Ref: 4Z-P-891

D-Penicillamine, USP grade

CAS: 52-67-5

Formula: C₅H₁₁NO₂S

Purezza: 97.0 - 102.0 %

Colore e forma: White to off-white powder or solid

Peso molecolare: 149.21

Ref: 7W-GA5612

D-Penicillamine

CAS: 52-67-5

Applications A Penicillin metabolite used in the treatment of Wilson’s disease, Cystinuria, Scleroderma and arsenic poisoning.
References Marti-Prats, L., et al.: Neurosci. Lett., 483, 143 (2010); Singh, A., et al.: J. Pharm. Sci., 99, 3931 (2010); Everette, J., et al.: J. Agric. Food Chem., 58, 8139 (2010);

Formula: C₅H₁₁NO₂S

Colore e forma: Neat

Peso molecolare: 149.21

Ref: TR-P223000

D-Penicillamine-d6

Prodotto controllato

CAS: 52-67-5

Applications D-Penicillamine-d6 is the isotope labelled analog of D-Penicillamine which is a Penicillin metabolite used in the treatment of Wilson’s disease, Cystinuria, Scleroderma and arsenic poisoning.
References Marti-Prats, L., et al.: Neurosci. Lett., 483, 143 (2010), Singh, A., et al.: J. Pharm. Sci., 99, 3931 (2010), Everette, J., et al.: J. Agric. Food Chem., 58, 8139 (2010),

Formula: C₅D₆H₅NO₂S

Colore e forma: Neat

Peso molecolare: 155.248

Ref: TR-P223002

H-D-Pen-OH

CAS: 52-67-5

M06142 - H-D-Pen-OH

Formula: C₅H₁₁NO₂S

Purezza: 95%

Colore e forma: Solid, White to off-white crystalline powder

Peso molecolare: 149.21

Ref: 10-M06142

D-Penicillamine-d6 (Racemic)

Prodotto controllato

CAS: 1795786-79-6, 2714436-24-3, 52-67-5

Formula: C₅H₅D₆NO₂S

Colore e forma: Neat

Peso molecolare: 155.25

Ref: TR-P223006

D-Penicillamine

CAS: 52-67-5

D-Penicillamine is a nonsteroidal anti-inflammatory drug that is used to treat bowel disease, including ulcerative colitis and Crohn's disease. It has also been used as a treatment for schizophrenia that is unresponsive to other treatments. D-Penicillamine binds covalently to reactive oxygen species (ROS), thereby preventing their interaction with proteins and DNA. The binding of ROS by D-penicillamine can be monitored using electrochemical impedance spectroscopy (EIS). The compound has also been shown to reduce the expression of bcl-2 protein in human cells, which may result in increased oxidative injury and rates of cell proliferation. D-Penicillamine has been shown to have therapeutic benefits for patients with primary sclerosing cholangitis, myocardial infarcts, or preparative high performance liquid chromatography (HPLC) analysis.

Formula: C₅H₁₁NO₂S

Purezza: Min 97%

Colore e forma: White Powder

Peso molecolare: 149.21 g/mol

Ref: 3D-FP26792