CAS 52299-14-6

Succinil-L-alanil-L-alanil-L-alanina p-nitroanilide

Descrizione:

Succinil-L-alanil-L-alanil-L-alanina p-nitroanilide è un substrato peptidico sintetico comunemente utilizzato in saggi biochimici, in particolare per la rilevazione di enzimi proteolitici come le serina proteasi. Questo composto presenta un gruppo succinile, che ne migliora la solubilità e stabilità, e un moiety di p-nitroanilina che funge da indicatore cromogeno. Dopo la scissione enzimatica, il rilascio di p-nitroanilina provoca un cambiamento di colore misurabile, consentendo la quantificazione dell'attività enzimatica. La struttura consiste in una sequenza di amminoacidi, specificamente residui di L-alanina, che contribuiscono alla sua specificità e interazione con le enzimi target. Il composto è tipicamente solubile in soluzioni acquose e mostra stabilità in condizioni di laboratorio standard. Il suo utilizzo in applicazioni di ricerca e diagnostica evidenzia la sua importanza nella comprensione della cinetica enzimatica e delle interazioni proteiche. Come per molti substrati peptidici, è necessario prestare attenzione alle condizioni di stoccaggio e manipolazione per mantenere la sua integrità e reattività.

Formula: C₁₉H₂₅N₅O₈

InChI: InChI=1S/C19H25N5O8/c1-10(20-15(25)8-9-16(26)27)17(28)21-11(2)18(29)22-12(3)19(30)23-13-4-6-14(7-5-13)24(31)32/h4-7,10-12H,8-9H2,1-3H3,(H,20,25)(H,21,28)(H,22,29)(H,23,30)(H,26,27)/t10-,11-,12-/m0/s1

InChI key: InChIKey=GVUGADOWXGKRAE-SRVKXCTJSA-N

SMILES: N(C([C@@H](NC([C@@H](NC([C@@H](NC(CCC(O)=O)=O)C)=O)C)=O)C)=O)C1=CC=C(N(=O)=O)C=C1

Sinonimi:

• 3-Carboxypropionyl-<span class="text-smallcaps">L</smallcap>-alanyl-<smallcap>L</smallcap>-alanyl-<smallcap>L</span>-alanine p-nitroanilide
• 43: PN: CN101457218 PAGE: 2 claimed protein
• <span class="text-smallcaps">L</smallcap>-Alaninamide, N-(3-carboxy-1-oxopropyl)-<smallcap>L</smallcap>-alanyl-<smallcap>L</span>-alanyl-N-(4-nitrophenyl)-
• Chromozym ELA
• N-(3-Carboxy-1-oxopropyl)-<span class="text-smallcaps">L</smallcap>-alanyl-<smallcap>L</smallcap>-alanyl-N-(4-nitrophenyl)-<smallcap>L</span>-alaninamide
• N-(3-carboxypropanoyl)-L-alanyl-L-alanyl-N-(4-nitrophenyl)-L-alaninamide
• N-SUCCINYL-(L-ALA)3-p-NITROANILIDE **03-32-0009**
• N-Succinyl-<span class="text-smallcaps">L</smallcap>-alanyl-<smallcap>L</smallcap>-alanyl-<smallcap>L</span>-alanine p-nitroanilide
• N-Succinyl-Ala-Ala-Ala-p-nitroanilide
• Suc-Ala-Ala-Ala-pNA
• Succinyl-<span class="text-smallcaps">L</smallcap>-alanyl-<smallcap>L</smallcap>-alanyl-<smallcap>L</span>-alanine 4-nitroanilide
• Succinyl-<span class="text-smallcaps">L</smallcap>-alanyl-<smallcap>L</smallcap>-alanyl-<smallcap>L</span>-alanine p-nitroanilide
• Succinyl-<span class="text-smallcaps">L</smallcap>-alanyl-<smallcap>L</smallcap>-alanyl-<smallcap>L</span>-alanyl p-nitroanilide
• Succinyl-<span class="text-smallcaps">L</span>-trialanine p-nitroanilide
• N-Succinyl-L-alanyl-L-alanyl-L-alanine p-nitroanilide
• 3-Carboxypropionyl-L-alanyl-L-alanyl-L-alanine p-nitroanilide
• L-Alaninamide, N-(3-carboxy-1-oxopropyl)-L-alanyl-L-alanyl-N-(4-nitrophenyl)-
• Succinyl-L-alanyl-L-alanyl-L-alanine p-nitroanilide

Suc-Ala-Ala-Ala-pNA

CAS: 52299-14-6

Suc-AAA-pNA, a readily soluble and sensitive substrate for human and rat neutrophil and porcine pancreatic elastases. The trialanine substrate is also hydrolyzed by proteinase K, subtilisins and thermitase as well as by astacin, a crayfish zinc-endopeptidase.

Formula: C₁₉H₂₅N₅O₈

Purezza: > 99%

Colore e forma: Light Yellow

Peso molecolare: 451.44

Ref: 01-4000902

SUC-ALA-ALA-ALA-PNA

CAS: 52299-14-6

Formula: C₁₉H₂₅N₅O₈

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 451.4305

Ref: IN-DA00D8ZJ

Suc-AAA-pNA

CAS: 52299-14-6

Suc-AAA-pNA is a synthetic peptide substrate commonly used for protease activity assays and widely applied in biochemical experiments.

Formula: C₁₉H₂₅N₅O₈

Purezza: 99.75%

Colore e forma: Solid

Peso molecolare: 451.43

Ref: TM-T205938

N-Succinyl-Ala-Ala-Ala-p-Nitroanilide

CAS: 52299-14-6

N-Succinyl-Ala-Ala-Ala-p-Nitroanilide

Purezza: 98%

Peso molecolare: 451.43g/mol

Ref: 54-OR1014482

Chromozym ELA

CAS: 52299-14-6

Formula: C₁₉H₂₅N₅O₈

Peso molecolare: 451.44

Ref: 4Z-A-248084

N-Succinyl-L-alanyl-L-alanyl-L-alanine 4-nitroanilide

CAS: 52299-14-6

N-Succinyl-L-alanyl-L-alanyl-L-alanine 4 nitroanilide is a synthetic substrate that has been shown to have proteolytic activity against dextran sulfate, collagen, and sephadex g-100. It also has insecticidal activity in that it inhibits the development of larvae of the insect Drosophila melanogaster. NSLAAALAALAAN can be used as a chemotactic agent for tissue culture cells. This synthetic substrate was also found to have antiinflammatory properties and may be useful in treating chronic bronchitis or other metabolic disorders.

Formula: C₁₉H₂₅N₅O₈

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 451.43 g/mol

Ref: 3D-FS46953

Suc-Ala-Ala-Ala-pNA

CAS: 52299-14-6

Suc-Ala-Ala-Ala-pNA is a protease inhibitor that is used in the treatment of metabolic disorders. It has been shown to have neurotrophic effects, which may be due to its ability to inhibit the activity of proteases, such as cathepsin B and proteinase 3. Suc-Ala-Ala-Ala-pNA has also been shown to have anti-inflammatory properties, which may be due to its ability to inhibit the activity of proinflammatory cytokines such as interleukin 1β, tumor necrosis factor α, and prostaglandin E2. Suc-Ala-Ala-Ala-pNA has long term efficacy in treating neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease.

Formula: C₁₉H₂₅N₅O₈

Purezza: Min. 95%

Peso molecolare: 451.43 g/mol

Ref: 3D-SAA-3071

Suc-Ala-Ala-Ala-pNA

Prodotto controllato

CAS: 52299-14-6

Formula: C₁₉H₂₅N₅O₈

Colore e forma: Neat

Peso molecolare: 451.43

Ref: TR-S224165

Suc-Ala-Ala-Ala-pNA

CAS: 52299-14-6

Suc-Ala-Ala-Ala-pNA is a peptide that binds to the acetylcholine receptor and activates it. This peptide has been shown to have potential as a research tool for studying the pharmacology of acetylcholine receptors in vitro. It has also been used as an inhibitor of neuronal ion channels, such as potassium channels, that are involved in the transmission of nerve impulses. Suc-Ala-Ala-Ala-pNA is not suitable for use in humans because it would be broken down by proteases before it could reach its target, but this peptide has applications in cell biology and neuroscience.

Formula: C₁₉H₂₅N₅O₈

Purezza: Min. 95%

Peso molecolare: 451.43 g/mol

Ref: 3D-SAA-3071-V