CAS 52509-14-5

(1,3-Diossolan-2-ilmetil)trifenilfosfonio bromuro

Descrizione:

(1,3-Diossolan-2-ilmetil)trifenilfosfonio bromuro è un sale di ammonio quaternario caratterizzato dal suo catione triphenylphosphonium e da un moiety di dioxolano. Questo composto appare tipicamente come un solido bianco a bianco sporco ed è solubile in solventi organici polari, il che facilita il suo utilizzo in varie reazioni chimiche. La presenza dell'anello di dioxolano contribuisce alla sua stabilità e reattività, rendendolo un intermedio utile nella sintesi organica, in particolare nella formazione di legami carbonio-carbonio. Il gruppo triphenylphosphonium aumenta la lipofilia, consentendo una migliore permeabilità della membrana nei sistemi biologici. Inoltre, l'anione bromuro funge da controione, che può influenzare la reattività e la solubilità del composto. Questa sostanza è spesso utilizzata in chimica organica sintetica, comprese le applicazioni nella sintesi di ylidi di fosfonio e altri derivati. Devono essere osservate precauzioni di sicurezza quando si maneggia questo composto, come con molti composti organofosforati, a causa della potenziale tossicità e reattività.

Formula: C₂₂H₂₂BrO₂P

InChI: InChI=1/C22H22O2P.BrH/c1-4-10-19(11-5-1)25(18-22-23-16-17-24-22,20-12-6-2-7-13-20)21-14-8-3-9-15-21;/h1-15,22H,16-18H2;1H/q+1;/p-1

InChI key: InChIKey=FRHRVQQUICVJDG-UHFFFAOYSA-M

SMILES: [P+](CC1OCCO1)(C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4.[Br-]

Sinonimi:

• (1,3-Dioxolane-2-Yl Methyl) Triphenyl Phosphonium Bromide
• 1,3-Dioxylany-2-yl)triphenylphosphonium bromide
• 2-[(1,3)-Dioxolane-2-Yl]-Methyltriphenylphosphonium Bromide
• Labotest-Bb Lt00233112
• Phosphonium, (1,3-Dioxolan-2-Ylmethyl)Triphenyl-, Bromide
• Phosphonium, (1,3-dioxolan-2-ylmethyl)triphenyl-, bromide (1:1)
• Triphenyl-1,3-Dioxolan-2-Ylmethyl-Phosphonium Bromide
• [(1,3-Dioxolan-2-yl)methyl]triphenylphosphanium bromide
• (1,3-Dioxolan-2-ylmethyl)triphenylphosphonium bromide
• (1,3-Dioxolan-2-ylmethyl)triphenylphosphonium bromide, 98 %
• 1,3-Dioxolan-2-ylmethyl-triphenylphosphanium bromide
• (1,3-DIOXOLAN-2-YLMETHYL)TRIPHENYLPHOSPHONIUM BROMIDE 98%

(1,3-Dioxolan-2-yl)methyltriphenylphosphonium Bromide

CAS: 52509-14-5

Formula: C₂₂H₂₂BrO₂P

Purezza: >97.0%(T)

Colore e forma: White to Light yellow to Light orange powder to crystal

Peso molecolare: 429.29

Ref: 3B-D2164

(1,3-Dioxolan-2-ylmethyl)triphenylphosphonium bromide, 98%

CAS: 52509-14-5

It finds its applications as a reagent for Wittig olefinations with introduction of a 1,3-dioxolane moiety. It is applied as a reactant for the preparation of a ratiometric fluorescent probe for specific detection of cysteine over homocysteine and glutathione, for microwave-assisted synthesis of KN-

Formula: C₂₂H₂₂BrO₂P

Purezza: 98%

Colore e forma: White to cream, Crystals or powder or crystalline powder

Peso molecolare: 429.29

Ref: 02-A18882

(1,3-Dioxolan-2-ylmethyl)triphenylphosphonium bromide

CAS: 52509-14-5

Formula: C₂₂H₂₂BrO₂P

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 429.2866

Ref: IN-DA0032B6

(1,3-Dioxolan-2-ylmethyl)(triphenyl)phosphonium bromide

CAS: 52509-14-5

(1,3-Dioxolan-2-ylmethyl)(triphenyl)phosphonium bromide

Formula: C₂₂H₂₂O₂P·Br

Purezza: 98%

Colore e forma: off-white solid

Peso molecolare: 429.29g/mol

Ref: 54-OR24913

(1,3-Dioxolan-2-yl)methyltriphenylphosphonium Bromide

CAS: 52509-14-5

(1,3-Dioxolan-2-yl)methyltriphenylphosphonium Bromide is a synthetic reagent that is used in the Wittig reaction. It is prepared by reacting p-toluenesulfonic acid with methylene chloride and methoxybenzene. This reagent can be used to synthesize β-unsaturated aldehydes from alkenes and hydroxylamine. The preparation of this reagent involves recrystallizing it from ethanol or ethyl acetate and then hydrogenating it to give (1,3-dioxolan-2-yl)methyl triphenylphosphonium bromide.

Formula: C₂₂H₂₂BrO₂P

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 429.29 g/mol

Ref: 3D-FD59861

(1,3-Dioxolan-2-ylmethyl)triphenylphosphonium bromide

CAS: 52509-14-5

Formula: C₂₂H₂₂BrO₂P

Purezza: 97%

Colore e forma: Solid, Powder

Peso molecolare: 429.294

Ref: 10-F067257

(1,3-Dioxolan-2-ylmethyl)triphenylphosphonium Bromide

Prodotto controllato

CAS: 52509-14-5

Applications (1,3-Dioxolan-2-ylmethyl)triphenylphosphonium Bromide is used as a reactant in the synthesis of ketolides methyloxoerythromycins with antibacterial activity as highly potent against macrolide-resistant and susceptible respiratory pathogens.
References Agouridas, C., et al.: J. Med. Chem., 41, 4080 (1998);

Formula: C₂₂H₂₂O₂P·Br

Colore e forma: Neat

Peso molecolare: 349.38+(79.90)

Ref: TR-D487065