CAS 529-35-1

5,6,7,8-Tetraidro-1-naftolo

Descrizione:

5,6,7,8-Tetraidro-1-naftolo, con il numero CAS 529-35-1, è un composto organico caratterizzato dalla sua struttura biciclica, che consiste in un sistema ad anelli di naftalene che ha subito una parziale idrogenazione. Questo porta a un composto saturo con un gruppo idrossile (-OH) attaccato a uno degli atomi di carbonio nel telaio del naftalene. Il composto è tipicamente un liquido o solido incolore o giallo pallido, a seconda della sua purezza e temperatura. È noto per le sue proprietà aromatiche ed è solubile in solventi organici, mentre è meno solubile in acqua a causa della sua natura idrofobica. 5,6,7,8-Tetraidro-1-naftolo è utilizzato in varie applicazioni, inclusa come intermedio nella sintesi organica e nella produzione di prodotti farmaceutici e fragranze. La sua reattività chimica è influenzata dalla presenza del gruppo idrossile, che può partecipare a legami idrogeno e altre reazioni chimiche. I dati di sicurezza indicano che deve essere maneggiato con cura, poiché può comportare rischi per la salute se ingerito o inalato.

Formula: C₁₀H₁₂O

InChI: InChI=1S/C10H12O/c11-10-7-3-5-8-4-1-2-6-9(8)10/h3,5,7,11H,1-2,4,6H2

InChI key: InChIKey=SCWNNOCLLOHZIG-UHFFFAOYSA-N

SMILES: OC1=C2C(=CC=C1)CCCC2

Sinonimi:

• 1,2,3,4-Tetrahydro-5-hydroxynaphthalene
• 1,2,3,4-Tetrahydro-5-naphthol
• 1,2,3,4-Tetrahydronaphthalen-5-ol
• 1-Hydroxy-5,6,7,8-tetrahydronaphthalene
• 1-Naphthalenol, 5,6,7,8-tetrahydro-
• 1-Naphthol, 5,6,7,8-tetrahydro-
• 5,6,7,8-Tetrahydro-1-hydroxynaphthalene
• 5,6,7,8-Tetrahydro-1-naphthalenol
• 5,6,7,8-Tetrahydro-alpha-naphthol
• 5,6,7,8-Tetrahydro-α-naphthol
• 5,6,7,8-Tetrahydronaphthalen-1-Ol
• 5,6,7,8-Tetrahydronaphthol
• 5-Hydroxytetralin
• Nsc 28822
• Tetrahydro-alpha-naphthol
• Tetrahydro-α-naphthol
• Tetralin-5-ol

5,6,7,8-Tetrahydro-1-naphthol

CAS: 529-35-1

Formula: C₁₀H₁₂O

Purezza: >98.0%(GC)

Colore e forma: White to Light yellow to Light orange powder to crystal

Peso molecolare: 148.21

Ref: 3B-T2816

5,6,7,8-Tetrahydro-1-naphthol, 99%

CAS: 529-35-1

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₁₀H₁₂O

Purezza: 99%

Colore e forma: White to cream to dark brown to pale cream to gray, Crystals or powder or crystalline powder or fused solid

Peso molecolare: 148.21

Ref: 02-L02416

5,6,7,8-Tetrahydro-1-naphthol

CAS: 529-35-1

Formula: C₁₀H₁₂O

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 148.2017

Ref: IN-DA003M96

5,6,7,8-Tetrahydro-1-naphthol

CAS: 529-35-1

Formula: C₁₀H₁₂O

Peso molecolare: 148.21

Ref: 7W-GL8471

5,6,7,8-Tetrahydronaphthalen-1-ol

CAS: 529-35-1

5,6,7,8-Tetrahydronaphthalen-1-ol

Purezza: 98%

Peso molecolare: 148.20g/mol

Ref: 54-OR914367

5,6,7,8-Tetrahydronaphthalen-1-ol

CAS: 529-35-1

Formula: C₁₀H₁₂O

Purezza: 95%

Colore e forma: Solid

Peso molecolare: 148.205

Ref: 10-F242836

5,6,7,8-Tetrahydro-1-naphthol

CAS: 529-35-1

5,6,7,8-Tetrahydro-1-naphthol is a natural compound that belongs to the group of diazonium compounds. It reacts with an alkanoic acid and a hydrochloric acid in the presence of a diazo compound to form an alkylating product. This product can be used as a precursor for the synthesis of other organic compounds. The reaction mechanism has been studied using rat liver microsomes. 5,6,7,8-Tetrahydro-1-naphthol can react with dopamine in human liver samples to form 1-hydroxyindole and phenylhydroxyl radicals (a reactive oxygen species). 5,6,7,8-Tetrahydro-1-naphthol also reacts with soybean lipoxygenase to produce an alkyl radical intermediate that can react with molecular oxygen to form peroxides.

Formula: C₁₀H₁₂O

Purezza: Min. 98 Area-%

Colore e forma: Powder

Peso molecolare: 148.2 g/mol

Ref: 3D-FT00059

5,6,7,8-Tetrahydro-1-naphthalenol

Prodotto controllato

CAS: 529-35-1

Applications 5,6,7,8-Tetrahydro-1-naphthalenol was used as a reagent in the synthesis of phosphonamidate and phosphonodiamidate prodrugs of adefovir and tenofovir which are used in the treatment of HIV infections. Also used in the synthesis of tetrahydronaphthalene-1-ol derivatives which were found to be promising potent antitumor agents.
References Pertusati, F., et al.: Eur. J. Med. Chem., 78, 259 (2014); Dong, Y., et al.: Bioorg. Med. Chem. Lett., 19, 6289 (2009);

Formula: C₁₀H₁₂O

Colore e forma: Neat

Peso molecolare: 148.2

Ref: TR-T294265