CAS 52950-18-2

Acido (-)-2-cloromandelico

Descrizione:

Acido (-)-2-cloromandelico è un composto organico caratterizzato dalla sua struttura chirale, che presenta un anello aromatico clorurato e un gruppo funzionale acido carbossilico. È un derivato dell'acido mandelico, in cui un atomo di cloro è sostituito nella seconda posizione dell'anello del benzene. Questo composto appare tipicamente come un solido cristallino bianco a bianco sporco ed è solubile in solventi polari come acqua e alcoli. La sua chiralità conferisce un'attività ottica specifica, rendendolo significativo in varie applicazioni, in particolare in farmacologia e sintesi organica. La presenza del gruppo acido carbossilico contribuisce alla sua acidità e reattività, permettendogli di partecipare a varie reazioni chimiche, tra cui esterificazione e amidazione. Inoltre, Acido (-)-2-cloromandelico può fungere da intermedio nella sintesi di altre molecole complesse, evidenziando la sua importanza nella chimica medicinale e nello sviluppo di farmaci chirali. I dati di sicurezza devono essere consultati per la manipolazione e lo stoccaggio, come per tutte le sostanze chimiche.

Formula: C₈H₇ClO₃

InChI: InChI=1/C8H7ClO3/c9-6-4-2-1-3-5(6)7(10)8(11)12/h1-4,7,10H,(H,11,12)/t7-/m0/s1

InChI key: InChIKey=RWOLDZZTBNYTMS-SSDOTTSWSA-N

SMILES: [C@@H](C(O)=O)(O)C1=C(Cl)C=CC=C1

Sinonimi:

• (-)-2-Chloromandelic acid
• (2R)-(2-chlorophenyl)(hydroxy)ethanoic acid
• (2R)-2-(2-Chlorophenyl)-2-(hydroxy)acetic acid
• (2S)-(2-chlorophenyl)(hydroxy)ethanoic acid
• (R)-(-)-2-Hydroxy-2-(2-chlorophenyl)acetic acid
• (R)-(2-Chlorophenyl)(hydroxy)acetic acid
• (R)-2-(2-Chlorophenyl)-2-hydroxyacetic acid
• (R)-2-(2-Chlorophenyl)-2-hydroxyethanoic acid
• (R)-o-Chloromandelic acid
• (αR)-2-Chloro-α-hydroxybenzeneacetic acid
• Benzeneacetic acid, 2-chloro-α-hydroxy-, (R)-
• Benzeneacetic acid, 2-chloro-α-hydroxy-, (αR)-
• D-(-)-2-Chloromandelic acid
• R-2-Chloromandelic Acid
• (R)-2-Chloromandelic acid
• R-(-)-2-Chloromandelic acid
• R-Chloromadelic acid
• 2-CHLORO-D-MANDELIC ACID
• (R )-(-)-2-chloromandellic acid
• (R)-(-)-2-CHLOROMANDELIC ACID 99%
• (R-chloromandelicacid)
• (R)-2-CHLORO-ALPHA-HYDROXYPHENYLACETIC ACID
• (R)-(-)-2-CHLOROMANDELIC ACID: CHIPROS 99%, EE 99%
• (R)-ORTHO-CHLOROMANDELIC ACID
• (R)-(-)-2-Chloromandelic acid, ChiPros 99+%, ee 99+%
• (2R)-2-(2-Chlorophenyl)-2-hydroxyacetic acid
• (r)-2-chloro-à-hydroxyphenylacetic acid
• (R)-(−
• (R)-(2-CHLORO-PHENYL)-HYDROXY-ACETIC ACID
• 2-CHLORO-MANDELIC ACID (R)
• (-)-o-Chloro-D-mandelic acid

2-Chloro-D-mandelic Acid

CAS: 52950-18-2

Formula: C₈H₇ClO₃

Purezza: >98.0%(GC)(T)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 186.59

Ref: 3B-C1663

(R)-(-)-2-Chloromandelic acid, ChiPros 99+%, ee 99+%

CAS: 52950-18-2

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₈H₇ClO₃

Purezza: 99+%

Colore e forma: White, crystalline powder

Peso molecolare: 186.59

Ref: 02-L19586

(R)-2-(2-Chlorophenyl)-2-hydroxyacetic acid

CAS: 52950-18-2

Formula: C₈H₇ClO₃

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 186.5924

Ref: IN-DA003C2Q

(R)-(-)-2-Chloromandelic acid

CAS: 52950-18-2

Formula: C₈H₇ClO₃

Purezza: ≥ 99.0%

Colore e forma: White to light yellow crystalline powder

Peso molecolare: 186.60

Ref: 7W-GK8180

(R)-(-)-2-Chloromandelic acid

CAS: 52950-18-2

(R)-(-)-2-Chloromandelic acid

Purezza: 98%

Peso molecolare: 186.59g/mol

Ref: 54-OR315005

(R)-2-Chloromandelic acid

CAS: 52950-18-2

Formula: C₈H₇ClO₃

Purezza: 98%

Colore e forma: Solid, Flakes

Peso molecolare: 186.59

Ref: 10-F011644

(R)-(-)-2-Chloromandelic Acid

Prodotto controllato

CAS: 52950-18-2

Applications Clopidogrel intermediate.
References Zhu, Shou-Fei; C., et al.: Nat. Chem., 2, 546 (2010), Sun, Y. et al.: Acta. Crys. Sec. E. Struct. Rep. On., E63, o2379 (2007);

Formula: C₈H₇ClO₃

Colore e forma: Neat

Peso molecolare: 186.59

Ref: TR-C367685

Clopidogrel Impurity 20

CAS: 52950-18-2

Formula: C₈H₇ClO₃

Peso molecolare: 186.6

Ref: ST-EA-CP-C2041

(R)-2-Chloromandelic acid

CAS: 52950-18-2

(R)-2-Chloromandelic acid is an organic compound with the formula CHClCOH. It is a mandelonitrile, which is a benzene ring fused to a nitrile. It has an optimal reaction at acidic pH and in organic solvents and is enantiopure. The cell lysis of Escherichia coli can be achieved by this compound, as seen through the use of acid dehydrogenase. (R)-2-Chloromandelic acid has been shown to inhibit platelet aggregation, making it an antiplatelet agent. This product can be synthesized using methods such as the enantioselective synthesis of clopidogrel or the asymmetric synthesis of D-mandelic acid methyl ester. The isolated yield for (R)-2-Chloromandelic acid is about 45%.

Formula: C₈H₇ClO₃

Purezza: Min. 95%

Colore e forma: Solid

Peso molecolare: 186.59 g/mol

Ref: 3D-FC03642