CAS 53-84-9

NAD

Descrizione:

NAD, o dinucleotide di nicotinamide adenina, è una coenzima cruciale presente in tutte le cellule viventi, svolgendo un ruolo vitale nei processi metabolici. Esiste in due forme: ossidata (NAD+) e ridotta (NADH). NAD+ è essenziale per le reazioni redox, facilitando il trasferimento di elettroni nella respirazione cellulare e nella produzione di energia. È coinvolto in vari percorsi biochimici, tra cui la glicolisi, il ciclo dell'acido citrico e la fosforilazione ossidativa. Inoltre, NAD+ funge da substrato per diversi enzimi, comprese le deidrogenasi, ed è importante per la riparazione del DNA e la segnalazione. La sostanza è un dinucleotide composto da due nucleotidi uniti dai loro gruppi fosfato, con un nucleotide contenente una base di adenina e l'altro contenente una base di nicotinamide. NAD è solubile in acqua e ha un peso molecolare relativamente basso. Il suo ruolo nel metabolismo cellulare e nel trasferimento di energia lo rende un componente critico per mantenere la salute e la funzione cellulare. A causa della sua importanza, NAD e i suoi derivati sono spesso studiati nel contesto dell'invecchiamento, dei disturbi metabolici e di varie malattie.

Formula: C₂₁H₂₇N₇O₁₄P₂

InChI: InChI=1S/C21H27N7O14P2/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(32)14(30)11(41-21)6-39-44(36,37)42-43(34,35)38-5-10-13(29)15(31)20(40-10)27-3-1-2-9(4-27)18(23)33/h1-4,7-8,10-11,13-16,20-21,29-32H,5-6H2,(H5-,22,23,24,25,33,34,35,36,37)/t10-,11-,13-,14-,15-,16-,20-,21-/m1/s1

InChI key: InChIKey=BAWFJGJZGIEFAR-NNYOXOHSSA-N

SMILES: O[C@H]1[C@H](N2C=3C(N=C2)=C(N)N=CN3)O[C@H](COP(OP(OC[C@H]4O[C@H]([C@H](O)[C@@H]4O)[N+]=5C=C(C(N)=O)C=CC5)(=O)[O-])(=O)O)[C@H]1O

Sinonimi:

• Adenine-nicotinamide dinucleotide
• Adenosine 5'-(trihydrogen diphosphate), 5'→5'-ester with 3-(aminocarbonyl)-1-β-D-ribofuranosylpyridinium hydroxide, inner salt
• Adenosine 5'-(trihydrogen diphosphate), P'→5'-ester with 3-(aminocarbonyl)-1-β-D-ribofuranosylpyridinium hydroxide, inner salt
• Adenosine 5'-(trihydrogen diphosphate), P'→5'-ester with 3-(aminocarbonyl)-1-β-D-ribofuranosylpyridinium, inner salt
• Adenosine 5′-(trihydrogen diphosphate), P′→5′-ester with 3-(aminocarbonyl)-1-β-<span class="text-smallcaps">D</span>-ribofuranosylpyridinium hydroxide, inner salt
• Adenosine 5′-(trihydrogen diphosphate), P′→5′-ester with 3-(aminocarbonyl)-1-β-<span class="text-smallcaps">D</span>-ribofuranosylpyridinium, inner salt
• Beta-Dpn
• Co-I
• Codehydrase I
• Codehydrogenase I
• Coenzyme I
• Cozymase
• Cozymase I
• DPN
• Diphosphopyridine nucleotide
• Enzopride
• NAD
• NAD⁺
• Nadid
• Nadida
• Nadide
• Nicotinamide adenine dinucleotide
• Nsc 20272
• Oxidized diphosphopyridine nucleotide
• Pyridinium, 3-carbamoyl-1-β-<span class="text-smallcaps">D</span>-ribofuranosyl-, hydroxide, 5′→5′-ester with adenosine 5′-(trihydrogen pyrophosphate), inner salt
• Pyridinium, 3-carbamoyl-1-β-D-ribofuranosyl-, hydroxide, 5'→5'-ester with adenosine 5'-(trihydrogen pyrophosphate), inner salt
• [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl [[(2R,3S,4R,5R)-5-(3-carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-oxido-phosphoryl] phosphate
• [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] [(2R,3S,4R,5R)-5-(3-carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl phosphate
• beta-Diphosphopyridine nucleotide
• beta-Nicotinamide adenine dinucleotide trihydrate
• β-Diphosphopyridine nucleotide
• β-NAD
• β-NAD⁺
• β-Nicotinamide Adenine Dinuclotide
• β-Nicotinamide adenine dinucleotide
• β-Nicotinamide adenine dinucleotide hydrate

β-Nicotinamide adenine dinucleotide, 97%

CAS: 53-84-9

NAD+, Free Acid is a major electron acceptor molecule in biological oxidation reactions. It is also used as a catalyst intermediate and several enzymes in a multistep system, known as enzyme cycling,. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portf

Formula: C₂₁H₂₇N₇O₁₄P₂

Purezza: 97%

Colore e forma: White to faint yellow, Powder

Peso molecolare: 663.43

Ref: 02-J62337

β-Nicotinamide Adenine Dinucleotide

CAS: 53-84-9

Formula: C₂₁H₂₇N₇O₁₄P₂

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 663.4251

Ref: IN-DA0034IM

NAD+

CAS: 53-84-9

NAD+ is a coenzyme that facilitates electron transfer in enzymatic reactions by alternating between oxidized (NAD+) and reduced (NADH) forms.

Formula: C₂₁H₂₇N₇O₁₄P₂

Purezza: 98.21% - 99.47%

Colore e forma: Off-White Solid Crystalline

Peso molecolare: 663.43

Ref: TM-T1609

Nicotinamide adenine dinucleotide

CAS: 53-84-9

Nicotinamide adenine dinucleotide

Formula: C₂₁H₂₇N₇O₁₄P₂

Purezza: >97% free acid

Colore e forma: Solid

Peso molecolare: 663.43g/mol

Ref: 54-BIB3011

NAD+

CAS: 53-84-9

NAD+

Purezza: ≥98%

Peso molecolare: 663.43g/mol

Ref: 54-BUP18555

β-Nicotinamide adenine dinucleotide

CAS: 53-84-9

Formula: C₂₁H₂₇N₇O₁₄P₂

Purezza: ≥ 95.0%

Colore e forma: White to light yellow crystalline powder

Peso molecolare: 663.43 (anhydrous)

Ref: 7W-GV0860

Nicotinamide Adenine Dinucleotide

CAS: 53-84-9

Formula: C₂₁H₂₇N₇O₁₄P₂

Peso molecolare: 663.43

Ref: 4Z-N-133021

β-Nicotinamide Adenine Dinucleotide

CAS: 53-84-9

Formula: C₂₁H₂₇N₇O₁₄P₂

Peso molecolare: 663.43

Ref: ST-EA-CP-N35008

b-Nicotinamide Adenine Dinucleotide-13C5

Prodotto controllato

CAS: 53-84-9

Formula: C₁₆₁₃C₅H₂₇N₇O₁₄P₂

Colore e forma: Neat

Peso molecolare: 668.39

Ref: TR-N407782

β-Nicotinamide Adenine Dinucleotide-d4 (d3 major)

Prodotto controllato

CAS: 53-84-9

Formula: C₂₁₂H₄H₂₃N₇O₁₄P₂

Colore e forma: White To Off-White

Peso molecolare: 667.45

Ref: TR-N407783

β-Nicotinamide Adenine Dinucleotide

CAS: 53-84-9

Formula: C₂₁H₂₇N₇O₁₄P₂

Colore e forma: Neat

Peso molecolare: 663.42

Ref: TR-N407784

β-Nicotinamide adenine dinucleotide

CAS: 53-84-9

Nicotinamide adenine dinucleotide (NAD), is a very important and essential coenzyme formed by the union of two nucleotides covalently bond to each other by their phosphates group. NAD is present in cells either in its oxidative form or in its reduced form, NAD+ and NADH respectively. They take part in many redox reactions, carrying electrons from one molecule to another.

Formula: C₂₁H₂₇N₇O₁₄P₂

Purezza: Min. 95 Area-%

Colore e forma: White Powder

Peso molecolare: 663.43 g/mol

Ref: 3D-NN11969

β-Nicotinamide Adenine Dinucleotide oxidized form [for Biochemical Research]

CAS: 53-84-9

Formula: C₂₁H₂₇N₇O₁₄P₂

Purezza: >95.0%(T)(HPLC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 663.43

Ref: 3B-D0919

ß-Nicotinamide Adenine Dinucleotide (Oxidized) (ß-NAD, DPN) extrapure, 98%

CAS: 53-84-9

Formula: C₂₁H₂₇N₇O₁₄P₂

Purezza: min. 98.0%

Colore e forma: White to off-white, Crystalline powder, Clear, Colourless to pale yellow

Peso molecolare: 663.44

Ref: SR-26759

ß-Nicotinamide Adenine Dinucleotide (Oxidized) (ß-NAD, DPN) ExiPlus, Multi-Compendial, 98%

CAS: 53-84-9

Formula: C₂₁H₂₇N₇O₁₄P₂

Purezza: min. 98.0%

Colore e forma: White to off-white, Crystalline powder, Clear, Colourless to pale yellow

Peso molecolare: 663.44

Ref: SR-19628

ß-Nicotinamide Adenine Dinucleotide (Oxidized) (ß-NAD, DPN) PrimeDx, 98%

CAS: 53-84-9

Formula: C₂₁H₂₇N₇O₁₄P₂

Purezza: min.98%

Colore e forma: White to off white, Crystalline powder, Clear, Colourless to pale yellow

Peso molecolare: 663.44

Ref: SR-86561

ß-Nicotinamide Adenine Dinucleotide (Oxidized) (ß-NAD, DPN) for molecular biology, 98%

CAS: 53-84-9

Formula: C₂₁H₂₇N₇O₁₄P₂

Purezza: min. 98.0%

Colore e forma: White to off - white, Crystalline powder, Clear, Colourless to pale yellow

Peso molecolare: 663.44

Ref: SR-87253

ß-Nicotinamide Adenine Dinucleotide (ß-NAD,DPN) for cell culture, 98%, Endotoxin (BET) 0.05EU/mg

CAS: 53-84-9

Formula: C₂₁H₂₇N₇O₁₄P₂

Purezza: min. 98.0%

Colore e forma: White to off-white, Crystalline powder, Clear, Colourless to pale yellow

Peso molecolare: 663.44

Ref: SR-64257

β-Nicotinamide Adenine Dinucleotide

CAS: 53-84-9

Purezza: 95+%

Colore e forma: Solid

Peso molecolare: 663.11

Ref: 10-F545316

β-Nicotinamide Adenine Dinucleotide Sodium Salt Hydrate

Prodotto controllato

CAS: 20111-18-6, 53-84-9

Stability Light Sensitive
Applications β-Nicotinamide Adenine Dinucleotide is a coeznyme consisting of an adenine base and a nicotinamide base connected by a pair of bridging phosphate group. β-Nicotinamide Adenine Dinucleotide acts as a coenzyme in redox reactions, as a donor of ADP-ribose moieties in ADP-ribosylation reactions and also as a precursor of the second messenger molecule cyclic ADP-ribose. β-Nicotinamide Adenine Dinucleotide also acts as a substrate for bacterial DNA ligases and a group of enzymes called sirtuins that use NAD+ to remove acetyl groups from proteins.
References Dudev, T. et al.: J. Am. Chem. Soc., 132, 16533 (2010); Kerbey, A. et al.: Biochem. J., 154, 327 (1976); Lahiri, S.D. et al.: ACS Chem. Biol., 7, 571 (2012);

Formula: C₂₁H₂₆N₇O₁₄P₂·Na·xH₂O

Purezza: >85%

Colore e forma: Neat

Peso molecolare: 685.41

Ref: TR-N407775