CAS 53-85-0

5,6-Dicloro-1-(β-D-ribofuranosil)benzimidazolo

Descrizione:

5,6-Dicloro-1-(β-D-ribofuranosil)benzimidazolo è un composto chimico caratterizzato dalla sua struttura, che include un nucleo di benzimidazolo sostituito con due atomi di cloro nelle posizioni 5 e 6 e un gruppo β-D-ribofuranosil nella posizione 1. Questo composto è noto per il suo ruolo come agente antivirale, in particolare nel contesto dell'inibizione della replicazione virale. Mostra proprietà tipiche dei derivati del benzimidazolo, come potenziali interazioni con acidi nucleici ed enzimi. La presenza del moiety ribofuranosil migliora la sua attività biologica facilitando l'incorporazione nelle strutture degli acidi nucleici. Il suo peso molecolare e le caratteristiche di solubilità possono variare in base al solvente utilizzato, ma è generalmente solubile in solventi polari. Il numero CAS del composto, 53-85-0, è un identificatore unico che aiuta nella sua classificazione e recupero nelle banche dati chimiche. In generale, 5,6-Dicloro-1-(β-D-ribofuranosil)benzimidazolo è significativo nella chimica medicinale e nella ricerca virologica.

Formula: C₁₂H₁₂Cl₂N₂O₄

InChI: InChI=1S/C12H12Cl2N2O4/c13-5-1-7-8(2-6(5)14)16(4-15-7)12-11(19)10(18)9(3-17)20-12/h1-2,4,9-12,17-19H,3H2/t9-,10-,11-,12-/m1/s1

InChI key: InChIKey=XHSQDZXAVJRBMX-DDHJBXDOSA-N

SMILES: O[C@H]1[C@H](N2C=3C(N=C2)=CC(Cl)=C(Cl)C3)O[C@H](CO)[C@H]1O

Sinonimi:

• 1-β-<span class="text-smallcaps">D</span>-Ribofuranosyl-5,6-dichlorobenzimidazole
• 1H-Benzimidazole, 5,6-dichloro-1-β-<span class="text-smallcaps">D</span>-ribofuranosyl-
• 5,6-Dichloro-1-(β-<span class="text-smallcaps">D</span>-ribofuranosyl)benzimidazole
• 5,6-Dichloro-1-b-D-ribofuranosylbenzimidazole
• 5,6-Dichloro-1-β-<span class="text-smallcaps">D</span>-ribofuranosyl-1H-benzimidazole
• 5,6-Dichlorobenzimidazole 1-beta-D-ribofuranoside
• 5,6-Dichlorobenzimidazole 1-β-<span class="text-smallcaps">D</span>-ribofuranoside
• 5,6-Dichlororibofuranosylbenzimidazole
• 5,6-dichloro-1-(beta-D-ribofuranosyl)-1H-benzimidazole
• 5,6-dichloro-1-[(2xi)-beta-D-threo-pentofuranosyl]-1H-benzimidazole
• 5,6-dichloro-1-pentofuranosyl-1H-benzimidazole
• Benzimidazole, 5,6-dichloro-1-<span class="text-smallcaps">D</span>-ribofuranosyl-
• Benzimidazole, 5,6-dichloro-1-β-<span class="text-smallcaps">D</span>-ribofuranosyl-
• NSC 401575
• Nqz-002
• 5,6-Dichloro-1-β-D-ribofuranosyl-1H-benzimidazole
• 5,6-Dichloro-1-(β-D-ribofuranosyl)benzimidazole
• 1H-Benzimidazole, 5,6-dichloro-1-β-D-ribofuranosyl-
• Benzimidazole, 5,6-dichloro-1-D-ribofuranosyl-

5,6-Dichlorobenzimidazole 1-β-D-Ribofuranoside

CAS: 53-85-0

Formula: C₁₂H₁₂Cl₂N₂O₄

Purezza: >98.0%(HPLC)(N)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 319.14

Ref: 3B-D4292

5,6-Dichlorobenzimidazole riboside, 98%

CAS: 53-85-0

Inhibits casein kinase II and blocks RNA synthesis. An adenosine analog.5,6-Dichlorobenzimidazole riboside is used as an inhibitor of RNA Polymerase II. It is nucleoside analogue and used in research to study the mechanisms of cellular regulation. Further, it inhibits some protein kinases. This The

Formula: C₁₂H₁₂Cl₂N₂O₄

Purezza: 98%

Colore e forma: White to pale cream, Powder

Peso molecolare: 319.14

Ref: 02-J64870

1H-Benzimidazole, 5,6-dichloro-1-b-D-ribofuranosyl-

CAS: 53-85-0

Formula: C₁₂H₁₂Cl₂N₂O₄

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 319.1407

Ref: IN-DA00I9GQ

5,6-Dichlorobenzimidazole 1-β-D-ribofuranoside

CAS: 53-85-0

5,6-Dichlorobenzimidazole 1-β-D-ribofuranoside

Peso molecolare: 319.14g/mol

Ref: 54-BIA8417

DRB

CAS: 53-85-0

DRB

Purezza: ≥98%

Peso molecolare: 319.14g/mol

Ref: 54-BUP11257

5,6-Dichlorobenzimidazole-1-b-D-ribofuranoside

CAS: 53-85-0

Formula: C₁₂H₁₂Cl₂N₂O₄

Peso molecolare: 319.14

Ref: 7W-GN4594

DRB

CAS: 53-85-0

DRB is a nucleoside analog that inhibits several carboxyl-terminal domain (CTD) kinases including casein kinase II (IC50 range of 4-10 μM)

Formula: C₁₂H₁₂Cl₂N₂O₄

Purezza: 99.46% - 99.83%

Colore e forma: White To Off-White Crystalline Solid

Peso molecolare: 319.14

Ref: TM-T7789

5,6-Dichloropurine-1-β-D-ribofuanosyl-H-benzimidazole

Prodotto controllato

CAS: 53-85-0

Applications An inhibitor of RNA synthesis (causes premature termination of transcription).
References Braedlye, J. and Sporns, O.: Brain Res., 815, 140 (1999), Ljungman, M., et al.: Oncogene, 18, 583 (1999), Roele, R.H., et al.: Oncogene, 18, 5765 (1999)

Formula: C₁₂H₁₂Cl₂N₂O₄

Colore e forma: Neat

Peso molecolare: 319.14

Ref: TR-D435820

5,6-Dichlorobenzimidazole-1-b-D-ribofuranoside

CAS: 53-85-0

5,6-Dichlorobenzimidazole-1-b-D-ribofuranoside is a chemical compound that has been shown to be neurotoxic in vitro. It has significant cytotoxicity against human leukemia cells (HL60) and induces neuronal death. This drug also inhibits the production of neurotrophic factors, which are vital for the normal development of neurons. 5,6-Dichlorobenzimidazole-1-b-D-ribofuranoside inhibits transcriptional regulation of genes that encode for receptors and enzymes. The compound is chemically stable and does not degrade easily by hydrolysis or oxidation. It can bind to polymerase chain reaction (PCR) primers and inhibit DNA synthesis. 5,6-Dichlorobenzimidazole-1-b-D-ribofuranoside also affects cell nuclei by inhibiting DNA synthesis and enzyme activities.

Formula: C₁₂H₁₂Cl₂N₂O₄

Purezza: Min. 98 Area-%

Colore e forma: White Powder

Peso molecolare: 319.15 g/mol

Ref: 3D-ND06701

(2R,3R,4S,5R)-2-(5,6-Dichloro-1H-benzo[d]imidazol-1-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol

CAS: 53-85-0

Purezza: 98%

Peso molecolare: 319.1400146

Ref: 10-F869536

5,6-Dichloro-1-β-D-ribofuranosylbenzimidazole

CAS: 53-85-0

Formula: C₁₂H₁₂Cl₂N₂O₄

Peso molecolare: 319.14

Ref: ST-EA-CP-A88075