CAS 532-40-1

Monofosfato di tiamina

Descrizione:

Monofosfato di tiamina, noto anche come fosfato di tiamina, è un derivato fosforilato della tiamina (vitamina B1). È caratterizzato dal suo ruolo di coenzima in varie reazioni biochimiche, in particolare nel metabolismo dei carboidrati. La sostanza è tipicamente una polvere cristallina bianca o bianco sporco che è solubile in acqua, il che facilita la sua attività biologica. Monofosfato di tiamina è essenziale per il corretto funzionamento degli enzimi coinvolti nella decarbossilazione degli acidi alfa-cheto e nel shunt del monofosfato di esoso. La sua presenza è cruciale per la produzione di energia e la sintesi dei neurotrasmettitori. In termini di stabilità, Monofosfato di tiamina è sensibile al calore e alle condizioni alcaline, il che può portare a degradazione. È comunemente usato in integratori alimentari e nella fortificazione di prodotti alimentari per prevenire la carenza di tiamina, che può portare a condizioni come il beriberi e la sindrome di Wernicke-Korsakoff. In generale, Monofosfato di tiamina svolge un ruolo vitale nel mantenimento della salute metabolica e nel supporto della funzione neurologica.

Formula: C₁₂H₁₈ClN₄O₄PS

InChI: InChI=1/C12H17N4O4PS.ClH/c1-8-11(3-4-20-21(17,18)19)22-7-16(8)6-10-5-14-9(2)15-12(10)13;/h5,7H,3-4,6H2,1-2H3,(H3-,13,14,15,17,18,19);1H

InChI key: InChIKey=GUGWNSHJDUEHNJ-UHFFFAOYSA-N

SMILES: C([N+]=1C(C)=C(CCOP(=O)(O)O)SC1)C=2C(N)=NC(C)=NC2.[Cl-]

Sinonimi:

• 2-(3-((6-Imino-2-methyl-1,6-dihydropyrimidin-5-yl)methyl)-4-methylthiazol-3-ium-5-yl)ethyl hydrogen phosphate hydrochloride
• 3-[(4-Amino-2-Methylpyrimidin-5-Yl)Methyl]-4-Methyl-5-[2-(Phosphonooxy)Ethyl]-1,3-Thiazol-3-Ium
• 3-[(4-Amino-2-Methylpyrimidin-5-Yl)Methyl]-4-Methyl-5-[2-(Phosphonooxy)Ethyl]-1,3-Thiazol-3-Ium Chloride
• Extraneurina
• Fosbione
• Monophosphothiamine
• Neurifosforil
• Novaneurina
• Novobeta
• Phosbitamin
• Phosphoric acid, thiamine ester
• Phosphothiamin
• Phosphothiamine
• Sineurina
• Superneurina
• TMP (thiamin ester)
• Thiamin monophosphate
• Thiamine monophosphate
• Thiamine monophosphate chloride
• Thiamine phosphate
• Thiamine phosphoric acid ester chloride
• Thiamine, dihydrogen phosphate (ester)
• Thiamine-P
• Thiazolium, 3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-4-methyl-5-[2-(phosphonooxy)ethyl]-, chloride
• Thiazolium, 3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-4-methyl-5-[2-(phosphonooxy)ethyl]-, chloride (1:1)
• Vitamin B1 monophosphate chloride
• Vitamin B₁ monophosphate
• Vitamin B₁ phosphate
• LABOTEST-BB LT00847627
• Phosphothiaminum
• Thiamin-p
• Thiamin monophosphate chloride
• 3-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-4-methyl-5-[2-(phosphonooxy)ethyl]thiazolium
• 3-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-4-methyl-5-(2-phosphonooxyethyl)thiazol-3-ium
• 3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-4-methyl-5-[2-(phosphonooxy)ethyl]-thiazolium chloride
• 3-((4-aMino-2-MethylpyriMidin-5-yl)Methyl)-4-Methyl-5-(2-(phosphonooxy)ethyl)thiazol-3-iuM chloride
• Phosphoric acid 2-[[3-[(2-methyl-4-amino-5-pyrimidinyl)methyl]-4-methylthiazolium]5-yl]ethyl ester
• 3-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-4-methyl-5-[2-(phosphonooxy)ethyl]thiazol-3-ium
• thiaminemonophosphate
• Thiamine-pi

Thiamine Phosphate Chloride

CAS: 532-40-1

Formula: C₁₂H₁₈N₄O₄PS·Cl

Colore e forma: White To Off-White Solid

Peso molecolare: 345.34 35.45

Ref: 4Z-T-8419

Thiamine monophosphate chloride

CAS: 532-40-1

Formula: C₁₂H₁₈N₄O₄PS·Cl

Colore e forma: White

Peso molecolare: 380.79

Ref: 04-C17455600

Vitamin B1 Monophosphate Chloride

CAS: 532-40-1

Applications Vitamin B1 Monophosphate Chloride is a precursor of thiamine pyrophosphate (T344070), a thiamine (T344185) derivative produced by enzyme thiamine pyrophosphatase. Thiamine pyrophosphate is a cofactor used to catalyze various biochemical reactions.
References Stuetz, W., et al.: PLoS One., 7, 36280 (2012); Liu, S.Q., et al.: J. Pharma. Exper. Therap., 341, 775 (2012);

Formula: C₁₂H₁₈N₄O₄PS·Cl

Colore e forma: White

Peso molecolare: 380.79

Ref: TR-V676015

Vitamin B1 monophosphate chloride

CAS: 532-40-1

Vitamin B1 monophosphate chloride is a metabolite of thiamine and is involved in the synthesis of nucleic acids, proteins, and lipids. It also plays an important role in energy metabolism. Vitamin B1 monophosphate chloride has been shown to have a matrix effect on axonal growth, which may be due to its ability to protect against oxidative stress by scavenging reactive oxygen species. It also has been shown to have a toxicological study that showed it was not mutagenic or carcinogenic (neither induced abnormal cell growth nor caused cancer) when administered orally to rats for 2 years at doses up to 1000 mg/kg body weight. The biological properties of Vitamin B1 monophosphate chloride are related to its ability to act as a cofactor for the enzyme pyruvate kinase, which is involved in glycolysis and gluconeogenesis, as well as being part of the pyridoxal phosphate-dependent transferase system that

Formula: C₁₂H₁₈ClN₄O₄PS

Purezza: Min. 95%

Peso molecolare: 380.79 g/mol

Ref: 3D-AAA53240