CAS 533876-30-1

SW063058

Prodotto controllato

CAS: 533876-30-1

SW063058 is a molecule that inhibits the activity of lipid kinases. It has been shown to be cytotoxic in vitro and induce autophagy, which may be due to its inhibition of cellular lipid metabolism. SW063058 also has significant cytotoxicity in cancer cells and induces apoptosis by inhibiting the activation of protein kinase B (Akt). The mechanism of action for SW063058 is not well understood but it is thought to inhibit allosteric modulators of lipid kinases, as well as an interaction with the cell membrane.

Formula: C₂₂H₁₅BrFIN₂O₂

Purezza: Min. 95%

Peso molecolare: 565.2 g/mol

Ref: 3D-IWA87630

SW063058

CAS: 533876-30-1

SW063058 is an autophagy inducer that specifically disrupts the interaction between Beclin 1 and Bcl-2 without affecting the interactions of Bcl-2 with pro-apoptotic members (such as Bax and BIM). By inhibiting the negative regulation of Beclin 1 (key to autophagy initiation) by Bcl-2, SW063058 enhances autophagic activity without inducing cytotoxicity, apoptosis, or other forms of cell death in vitro.

Formula: C₂₂H₁₅BrFIN₂O₂

Colore e forma: Solid

Peso molecolare: 565.17

Ref: TM-T200877