CAS 5355-48-6

Card-20(22)-enolide, 3-[(O-4-O-acetil-2,6-didesossi-β-d-ribo-esopiranosil-(1→4)-O-2,6-didesossi-β-d-ribo-esopiranosil-(1→4)-2,6-didesossi-β-d-ribo-esopiranosil)ossi]-12,14-diidrossi-, (3β,5β,12β)-

Descrizione:

Card-20(22)-enolide, con il numero CAS 5355-48-6, è un composto organico complesso appartenente alla classe dei cardenolidi, che sono glicosidi steroidei. Questa sostanza presenta uno scheletro steroideo con più gruppi idrossilici, specificamente nelle posizioni 12 e 14, contribuendo alla sua attività biologica. La presenza di una struttura glicosidica unica, composta da tre unità di dideossi-β-D-ribo-esopiranosil collegate tramite legami (1→4), migliora la sua solubilità e le potenziali interazioni con i sistemi biologici. Il gruppo acetile nella posizione 4 della prima unità di zucchero modifica ulteriormente le sue proprietà, influenzando potenzialmente la sua farmacocinetica e bioattività. I cardenolidi sono noti per i loro effetti sulla funzione cardiaca, spesso utilizzati in applicazioni medicinali, in particolare nel trattamento di condizioni cardiache. La stereochimica specifica indicata dalla configurazione (3β,5β,12β) è cruciale per la sua attività biologica, poiché determina l'interazione del composto con i bersagli cellulari. In generale, Card-20(22)-enolide esemplifica l'intricato rapporto tra struttura e funzione nei prodotti naturali bioattivi.

Formula: C₄₃H₆₆O₁₅

InChI: InChI=1/C43H66O15/c1-20-38(55-23(4)44)30(45)17-36(53-20)57-40-22(3)54-37(18-32(40)47)58-39-21(2)52-35(16-31(39)46)56-26-9-11-41(5)25(14-26)7-8-28-29(41)15-33(48)42(6)27(10-12-43(28,42)50)24-13-34(49)51-19-24/h13,20-22,25-33,35-40,45-48,50H,7-12,14-19H2,1-6H3

InChI key: InChIKey=NREAGDHHMSOWKZ-DXJNJSHLSA-N

SMILES: O[C@@]12[C@]3([C@@]([C@]4(C)[C@](CC3)(C[C@@H](O[C@H]5C[C@H](O)[C@H](O[C@H]6C[C@H](O)[C@H](O[C@H]7C[C@H](O)[C@H](OC(C)=O)[C@@H](C)O7)[C@@H](C)O6)[C@@H](C)O5)CC4)[H])(C[C@@H](O)[C@]1(C)[C@H](CC2)C=8COC(=O)C8)[H])[H]

Sinonimi:

• (3β,5β,12β)-3-[(O-4-O-Acetyl-2,6-dideoxy-β-<span class="text-smallcaps">D</smallcap>-ribo-hexopyranosyl-(1→4)-O-2,6-dideoxy-β-<smallcap>D</smallcap>-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-<smallcap>D</span>-ribo-hexopyranosyl)oxy]-12,14-dihydroxycard-20(22)-enolide
• 16'-Acetyldigoxin
• 3-{[4-O-acetyl-2,6-dideoxyhexopyranosyl-(1->4)-2,6-dideoxyhexopyranosyl-(1->4)-2,6-dideoxyhexopyranosyl]oxy}-12,14-dihydroxycard-20(22)-enolide
• 4'''-Acetyldigoxin
• Acetyl-digoxin-beta
• Card-20(22)-enolide, 3-((O-4-O-acetyl-2,6-dideoxy-beta-d-ribo-hexopyranosyl-(1.4)-O-2,6-dideoxy-beta-d-ribo-hexopyranosyl-(1.4)-2,6-dideoxy-beta-d-ribo-hexopyranosyl)oxy)-12,14-dihydroxy-, (3beta,5beta,12beta)-
• Card-20(22)-enolide, 3-[(O-4-O-acetyl-2,6-dideoxy-β-<span class="text-smallcaps">D</smallcap>-ribo-hexopyranosyl-(1→4)-O-2,6-dideoxy-β-<smallcap>D</smallcap>-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-<smallcap>D</span>-ribo-hexopyranosyl)oxy]-12,14-dihydroxy-, (3β,5β,12β)-
• Cardioreg
• Cor-Puren
• Digorid B
• Digotab
• Digoxigenin + zuckerkette wie bei acetyl-digitoxin-alpha
• Digoxigenin + zuckerkette wie bei acetyl-digitoxin-alpha [German]
• Digoxigenin tridigitoxoside-β-acetate
• Digoxin Didier
• Digoxin, 4'''-acetate (8CI)
• Digoxin, 4′′′-acetate
• Digoxin, acetate, beta-
• Hexamethyleneimine 3,5-dinitrobenzoate
• Kardiamed
• Longdigox
• Novodigal
• Stillacor
• beta-Acetyldigoxin
• β-Acetodigoxin
• β-Acetyldigoxin
• Card-20(22)-enolide, 3-[(O-4-O-acetyl-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-D-ribo-hexopyranosyl)oxy]-12,14-dihydroxy-, (3β,5β,12β)-
• (3β,5β,12β)-3-[(O-4-O-Acetyl-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-D-ribo-hexopyranosyl)oxy]-12,14-dihydroxycard-20(22)-enolide
• hexamethyleneimine3,5-dinitrobenzoate
• ACETYLDIGOXIN, B-
• -acetyldigoxin for peak identification CRS
• β-Acetyl Digoxin
• -Acetyldigoxin CRS
• BETA-ACETYLDIGOXIN USP/EP/BP
• 2-Acetyl Digoxin
• Acetyldigoxin research grade
• Digoxin Impurity 10(Digoxin EP Impurity J)
• 3β-[[4-O-[4-O-(4-O-Acetyl-2,6-dideoxy-β-D-ribo-hexopyranosyl)-2,6-dideoxy-β-D-ribo-hexopyranosyl]-2,6-dideoxy-β-D-ribo-hexopyranosyl]oxy]-12β,14-dihydroxy-5β-card-20(22)-enolide
• 3β-[4-O-[4-O-(4-O-Acetyl 2,6-dideoxy-β-D-ribo-hexopyranosyl)-2,6-dideoxy-β-D-ribo-hexopyranosyl]-2,6-dideoxy-β-D-ribo-hexopyranosyloxy]-12β,14-dihydroxy-5β,14β-carda-20(22)-enolide
• digoxigenin+zuckerkettewiebeiacetyl-digitoxin-alpha
• (3β,5β,12β)-3-[(O-4-O-Αcetyl-2,6-dideoxy-β-D-ribo-hexopyranosyl-(14)-O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(14)-2,6-dideoxy-β-D-ribo-hexopyranosyl)oxy]-12,14-dihydroxycard-20(22)-enolide
• digoridb
• Digoxin IMpurity J
• Digoxin EP Impurity J

β-ACETYLDIGOXIN FOR PEAK IDENTIFICATION CRS

CAS: 5355-48-6

β-ACETYLDIGOXIN FOR PEAK IDENTIFICATION CRS

Formula: C₄₃H₆₆O₁₅

Peso molecolare: 822.9751

Ref: 41-Y0000642

β-ACETYLDIGOXIN CRS

CAS: 5355-48-6

β-ACETYLDIGOXIN CRS

Formula: C₄₃H₆₆O₁₅

Colore e forma: White.

Peso molecolare: 822.9751

Ref: 41-Y0000565

b-Acetyl digoxin

CAS: 5355-48-6

Formula: C₄₃H₆₆O₁₅

Purezza: ≥ 98.0%

Colore e forma: White solid

Peso molecolare: 822.98

Ref: 7W-GC5455

Digoxin EP Impurity J

CAS: 5355-48-6

Formula: C₄₃H₆₆O₁₅

Peso molecolare: 823.00

Ref: 4Z-D-759

β-Acetyl Digoxin

Prodotto controllato

CAS: 5355-48-6

Applications Digoxin derivative, a cardiotonic glycosides steroid.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Yoshida, F., et al.: J. Med. Chem., 43, 2575 ( 2000), Turner, J., et al.: Pharm. Res., 21, 68 (2004), Wang, J., et al.: Anal. Chim. Acta, 601, 156 (2007),

Formula: C₄₃H₆₆O₁₅

Colore e forma: Neat

Peso molecolare: 822.98

Ref: TR-A173665

β-Acetyldigoxin

CAS: 5355-48-6

β-Acetyldigoxin is a cardiac glycoside, which is a naturally derived chemical compound primarily sourced from Digitalis lanata, a species of the foxglove plant. These compounds exert their effects by inhibiting the Na+/K+-ATPase enzyme, leading to an increase in intracellular calcium concentrations. This mechanism enhances myocardial contractility, contributing to its positive inotropic effects, which are essential in treating heart-related ailments.

Formula: C₄₃H₆₆O₁₅

Purezza: Min. 95%

Peso molecolare: 822.98 g/mol

Ref: 3D-OA164421

Digoxin EP Impurity J

CAS: 5355-48-6

Formula: C₄₃H₆₆O₁₅

Peso molecolare: 823

Ref: ST-EA-CP-D1200009