CAS 53846-50-7

(-)-8-Prenilnaringenina

Descrizione:

(-)-8-Prenilnaringenina è un flavonoide che si trova naturalmente, specificamente un derivato prenilato della naringenina, presente in varie piante, in particolare nei luppoli (Humulus lupulus). Questo composto è caratterizzato dalla sua struttura unica, che include un gruppo prenilico che ne migliora l'attività biologica. Mostra un'attività estrogenica significativa, rendendolo di interesse negli studi relativi alla modulazione ormonale e alle potenziali applicazioni terapeutiche in condizioni influenzate dagli estrogeni. Inoltre, (-)-8-Prenilnaringenina è stato studiato per le sue proprietà antiossidanti, che possono contribuire ai suoi effetti protettivi contro lo stress ossidativo. Il composto è tipicamente solubile in solventi organici e ha una solubilità limitata in acqua, comune a molti flavonoidi. I suoi potenziali benefici per la salute, insieme al suo ruolo nei meccanismi di difesa delle piante, lo rendono oggetto di ricerca continua sia in farmacologia che in nutrizione. In generale, (-)-8-Prenilnaringenina rappresenta un esempio affascinante di come i composti derivati dalle piante possano influenzare la salute e la malattia umana.

Formula: C₂₀H₂₀O₅

InChI: InChI=1S/C20H20O5/c1-11(2)3-8-14-15(22)9-16(23)19-17(24)10-18(25-20(14)19)12-4-6-13(21)7-5-12/h3-7,9,18,21-23H,8,10H2,1-2H3/t18-/m0/s1

InChI key: InChIKey=LPEPZZAVFJPLNZ-SFHVURJKSA-N

SMILES: O=C1C=2C(=C(CC=C(C)C)C(O)=CC2O)O[C@@H](C1)C3=CC=C(O)C=C3

Sinonimi:

• 4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-8-(3-methyl-2-buten-1-yl)-, (2S)-
• 4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-8-(3-methyl-2-butenyl)-, (2S)-
• Flavaprenin
• 4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-8-(3-methyl-2-butenyl)-, (S)-
• (2S)-2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-8-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one
• (2S)- 2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-8-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one
• (-)-8-Prenylnaringenin
• Phloroglucinol Impurity Y
• 5,7-dihydroxy-2-(4-hydroxyphenyl)-8-(3-methylbut-2-enyl)-2,3-dihydrochromen-4-one
• Flavaprenin (8-Prenylnaringenin, Sophorafl)
• (2S)-5,7-dihydroxy-2-(4-hydroxyphenyl)-8-(3-methylbut-2-enyl)-2,3-dihydrochromen-4-one

8-?Prenylnaringenin

CAS: 53846-50-7

Formula: C₂₀H₂₀O₅

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 340.3698

Ref: IN-DA00DGPX

8-​Prenylnaringenin

CAS: 53846-50-7

8-​Prenylnaringenin

Purezza: ≥98%

Peso molecolare: 340.37g/mol

Ref: 54-BUP02709

8-Prenylnaringenin

CAS: 53846-50-7

8-Prenylnaringenin is a phytoestrogen with high estrogenic activity, it shows more potent effects on promoting osteoblastic bone formation and inhibiting osteoclastic bone resorption by ERα instead of ERβ than the two classic phytoestrogens: genistein and daidzein. 8-Prenylnaringenin at all assayed doses (0.001-20 µM) presumably improves mitochondrial function, whereas a high dose of XN (5 µM) worsens the functionality of this organelle.

Formula: C₂₀H₂₀O₅

Purezza: 95%~99%

Peso molecolare: 340.375

Ref: BP-SBP02804

8-Prenylnaringenin

CAS: 53846-50-7

Formula: C₂₀H₂₀O₅

Peso molecolare: 340.38

Ref: 7W-GY1353

8-​Prenylnaringenin

CAS: 53846-50-7

8-Prenylnaringenin is a phytoestrogen with high estrogenic activity,

Formula: C₂₀H₂₀O₅

Purezza: 98.26% - 99.46%

Colore e forma: Solid

Peso molecolare: 340.37

Ref: TM-TN1146

Flavaprenin (8-Prenylnaringenin, Sophorafl)

CAS: 53846-50-7

Formula: C₂₀H₂₀O₅

Peso molecolare: 340.38

Ref: 4Z-P-249008

(-)-8-Prenylnaringenin

CAS: 53846-50-7

Applications (-)-8-Prenylnaringin is a prenylflavonoid, a class on non-steroidal phytoestrogen that mimicks and/or modulating endogenous estrogens via estrogen receptor binding.
References Miyamoto, M. et al.: Planta Med., 64, 516 (1998); Kim, H.J. et al.: Arch. Pharm. Res., 31, 1241 (2008); Zierau, O. et al.: Mol. Cell. Endocrinol., 294, 92 (2008);

Formula: C₂₀H₂₀O₅

Colore e forma: Neat

Peso molecolare: 340.37

Ref: TR-P712890

8-Prenylnaringenin

CAS: 53846-50-7

8-Prenylnaringenin is a flavonoid compound, which is a naturally occurring phytoestrogen. It is primarily found in hops (Humulus lupulus), a plant commonly used in brewing beer. The compound is known for its high estrogenic activity, which is attributed to its ability to bind to estrogen receptors, particularly the estrogen receptor alpha.

Formula: C₂₀H₂₀O₅

Purezza: Min. 98 Area-%

Colore e forma: Powder

Peso molecolare: 340.37 g/mol

Ref: 3D-FP64928