CAS 54-71-7
:Cloridrato di pilocarpina
Descrizione:
Cloridrato di pilocarpina è un farmaco utilizzato principalmente per trattare condizioni come il glaucoma e la bocca secca (xerostomia). È un alcaloide sintetico derivato dalle foglie della pianta Pilocarpus. Come sale cloridrato, è tipicamente presentato come una polvere cristallina bianca o bianco sporco solubile in acqua. La pilocarpina agisce come un agonista muscarinico, stimolando il sistema nervoso parasimpatico, il che porta a un aumento della salivazione e della lacrimazione, oltre a una riduzione della pressione intraoculare facilitando il deflusso dell'umore acqueo. Il composto ha un peso molecolare relativamente basso e presenta un pKa moderato, indicando il suo comportamento come una base debole. I suoi effetti farmacologici possono portare a effetti collaterali come sudorazione, aumento della salivazione e disturbi gastrointestinali. A causa del suo meccanismo d'azione, la pilocarpina è controindicata in pazienti con determinate condizioni, come asma o altri problemi respiratori, dove l'aumento delle secrezioni potrebbe rappresentare un rischio. In generale, Cloridrato di pilocarpina è un agente terapeutico prezioso in contesti medici specifici.
Formula:C11H17ClN2O2
InChI:InChI=1/C11H16N2O2/c1-3-10-8(6-15-11(10)14)4-9-5-12-7-13(9)2/h5,7-8,10H,3-4,6H2,1-2H3/t8-,10-/m0/s1
InChI key:InChIKey=RNAICSBVACLLGM-GNAZCLTHSA-N
SMILES:C([C@@H]1[C@H](CC)C(=O)OC1)C=2N(C)C=NC2.Cl
Sinonimi:- (3S,4R)-3-ethyl-4-[(1-methyl-1H-imidazol-5-yl)methyl]dihydrofuran-2(3H)-one
- (3S,4R)-3-ethyl-4-[(1-methyl-1H-imidazol-5-yl)methyl]dihydrofuran-2(3H)-one hydrochloride (1:1)
- 2(3H)-Furanone, 3-ethyldihydro-4-[(1-methyl-1H-imidazol-5-yl)methyl]-, hydrochloride (1:1), (3S,4R)-
- 2(3H)-Furanone, 3-ethyldihydro-4-[(1-methyl-1H-imidazol-5-yl)methyl]-, monohydrochloride, (3S,4R)-
- 2(3H)-Furanone, 3-ethyldihydro-4-[(1-methyl-1H-imidazol-5-yl)methyl]-, monohydrochloride, (3S-cis)-
- Adsorbocarpine
- Almocarpine
- Isopto Carpine
- Nsc 5746
- Pilocar
- Pilocar SMP
- Pilocarpal
- Pilocarpina, Clorhidrato
- Pilocarpine Hcl
- Pilocarpine chloride
- Pilocarpine muriate
- Pilocarpine, chlorhydrate
- Pilocarpine, monohydrochloride
- Pilocarpinhydrochlorid
- Pilocarpinium chloride
- Pilocel
- Pilogel
- Pilovisc
- Salagen
- Sanpilo
- Vistacarpin N
- Pilocarpine hydrochloride
- Pilocarpine hydrochloride
- 3-ETHYL-4-[(1-METHYL-5-IMIDAZOLYL)METHYL]TETRAHYDROFURAN-2-ONE HYDROCHLORIDE
- 3-ethyldihydro-4-[(1-methyl-1h-imidazol-5-yl)methyl]-2(3h)-furanonmonohydr
- pilomiotin
- (3S-CIS)-3-ETHYLDIHYDRO-4-[(1-METHYL-1H-IMIDAZOL-5-YL)METHYL]-2(3H)-FURANONE HYDROCHLORIDE
- (3s-cis)-ochlorid
- pilocarpinemuriate
- 3-ethyldihydro-4-[(1-methyl-1H-imidazol-5-yl)methyl]-,monohydrochloride,(3S-cis)-2(3H)-Furanone
- mi-piloophthsol
- ALMOCARPINE HYDROCHLORIDE
- amisturap
- (3S,4R)-4,5-DIHYDRO-3-ETHYL-4-(1-METHYL-1H-IMIDAZOL-5-YLMETHYL)-2(3H)-FURANONE HYDROCHLORIDE
- Vedi altri sinonimi
Ordinare per
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13 prodotti.
Pilocarpine Hydrochloride
CAS:Formula:C11H16N2O2·HClPurezza:>98.0%(T)(HPLC)Colore e forma:White to Almost white powder to crystalPeso molecolare:244.72PILOCARPINE HYDROCHLORIDE CRS
CAS:<p>PILOCARPINE HYDROCHLORIDE CRS</p>Formula:C11H16N2O2Colore e forma:Crystalline Powder. White. Colourless. Powder.Peso molecolare:208.2569Pilocarpine Hydrochloride
CAS:<p>Other alkaloids,natural or reproduced by synthesis, and their salts, ethers,esters&other derivatives, nesoi</p>Formula:C11H16N2O2·ClHColore e forma:Colorless Translucent White PowderPeso molecolare:244.09786(3S,4R)-3-Ethyldihydro-4-[(1-methyl-1H-imidazol-5-yl)methyl]-2(3H)-furanone hydrochloride
CAS:Formula:C11H17ClN2O2Purezza:99%Colore e forma:SolidPeso molecolare:244.7179Pilocarpine Hydrochloride
CAS:<p>Pilocarpine Hydrochloride (NSC 5746 HCl) is an M3-type muscarinic acetylcholine receptor agonist. High-Quality, Low-Cost!</p>Formula:C11H16N2O2·HClPurezza:98% - 99.89%Colore e forma:Oil Or Crystals SolidPeso molecolare:244.72(+)-Pilocarpine hydrochloride
CAS:Formula:C11H16N2O2HClPurezza:(anhydrous basis) EP 99.0 - 101.0 %, USP 98.0 - 102.0 %Colore e forma:Colourless, white or almost white crystalline powder or crystals, hygroscopicPeso molecolare:244.72Pilocarpine hydrochloride
CAS:Natural alkaloidFormula:C11H16N2O2HClPurezza:≥ 95.0 % (HPLC)Colore e forma:PowderPeso molecolare:244.72Pilocarpine hydrochloride
CAS:<p>Pilocarpine hydrochloride is a cholinergic agonist, which is a derivative of the natural alkaloid pilocarpine. This compound is sourced from the leaves of the *Pilocarpus* species, particularly *Pilocarpus microphyllus* and *Pilocarpus jaborandi*. Its mode of action involves the stimulation of muscarinic receptors, primarily M3 receptors, which leads to increased secretion from exocrine glands and smooth muscle stimulation. In ophthalmology, pilocarpine hydrochloride is utilized to manage conditions such as glaucoma and ocular hypertension by inducing miosis to improve aqueous humor outflow and reduce intraocular pressure. Additionally, it is applied in the treatment of xerostomia (dry mouth), particularly in patients suffering from Sjögren's syndrome or those undergoing radiation therapy, by enhancing salivary gland secretion. Its clinical applications underscore its importance as a tool in both ocular and salivary gland dysfunction management.</p>Formula:C11H17ClN2O2Purezza:Min. 95%Colore e forma:White PowderPeso molecolare:244.72 g/molPilocarpine Hydrochloride
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications Antiglaucoma agent; miotic; sialogogue.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Al-Badr, A.A., et al.: Anal. Profiles Drug Subs., 12, 385 (1983), Vivino, F.B., et al.: Arch. Intern. Med., 159, 174 (1999), Horiot, J.-C., et al.: Radiother. Oncol., 55, 233 (2000),<br></p>Formula:C11H16N2O2·ClHColore e forma:White To Off-WhitePeso molecolare:244.72
![(3S,4R)-3-Ethyldihydro-4-[(1-methyl-1H-imidazol-5-yl)methyl]-2(3H)-furanone hydrochloride](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA003BD9.jpg&w=3840&q=75)
