CAS 549-02-0

10β,17β-dihydroxyestra-1,4-dien-3-one

CAS: 549-02-0

10β,17β-dihydroxyestra-1,4-dien-3-one

Purezza: ≥95%

Peso molecolare: 288.38g/mol

Ref: 54-BUP21741

DHED

Prodotto controllato

CAS: 549-02-0

DHED is a neuroactive steroid precursor, specifically a bioprecursor prodrug of estradiol, which is derived from chemical synthesis pathways. It is unique in its targeted mode of action, as it selectively converts to the active hormone estradiol within the brain via enzymatic processes that occur in situ. This specificity is facilitated by 17β-hydroxysteroid dehydrogenase type 1, which catalyzes the conversion of DHED to estradiol exclusively in the brain, minimizing peripheral estrogenic effects.

Formula: C₁₈H₂₄O₃

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 288.38 g/mol

Ref: 3D-XD179457

10,17β-Dihydroxy-estra-1,4-dien-3-one

Prodotto controllato

CAS: 549-02-0

Applications 10,17β-Dihydroxy-estra-1,4-dien-3-one is a prodrug that can be converted to the main human estrogen, 17β-estradiol, in the brain and not elsewhere in the body due to an enzyme expressed only in the brain. It provides positive estrogenic effects on the brain and relieve symptoms in patients with a broad range of central nervous system diseases without side effects in other tissues.
References Prokai, L., et al.: Sci. Transl. Med., 7, 297 (2015)

Formula: C₁₈H₂₄O₃

Colore e forma: Neat

Peso molecolare: 288.381

Ref: TR-D454120

10,17β-Dihydroxy-estra-1,4-dien-3-one

CAS: 549-02-0

Formula: C₁₈H₂₄O₃

Peso molecolare: 288.39

Ref: ST-EA-CP-E28040

10β,17β-dihydroxyestra-1,4-dien-3-one

CAS: 549-02-0

10β,17β-dihydroxyestra-1,4-dien-3-one (DHED) has neuroprotective effects, can improve cognitive dysfunction, and can be used to study brain injury.

Formula: C₁₈H₂₄O₃

Colore e forma: Solid

Peso molecolare: 288.38

Ref: TM-T10036