CAS 5591-45-7

Tiotixene

Descrizione:

Tiotixene è un farmaco antipsicotico utilizzato principalmente nel trattamento della schizofrenia e di altri disturbi psicotici. Appartiene alla classe dei tioxanteni e funziona come antagonista dei recettori della dopamina, mirando in particolare ai recettori D2 nel cervello. Questa azione aiuta ad alleviare sintomi come allucinazioni e deliri. Tiotixene è caratterizzato dalla sua struttura chimica, che include un nucleo di tioxantene, contribuendo alle sue proprietà farmacologiche. La sostanza è tipicamente somministrata per via orale ed è nota per i suoi potenziali effetti collaterali, che possono includere sedazione, aumento di peso e sintomi extrapiramidali. È importante monitorare i pazienti per questi effetti durante il trattamento. Inoltre, Tiotixene ha una emivita relativamente lunga, consentendo una somministrazione una o due volte al giorno. Come con tutti i farmaci antipsicotici, è essenziale considerare attentamente il profilo rischio-beneficio e deve essere prescritto sotto la guida di un professionista sanitario qualificato.

Formula: C₂₃H₂₉N₃O₂S₂

InChI: InChI=1/C23H29N3O2S2/c1-24(2)30(27,28)18-10-11-23-21(17-18)19(20-7-4-5-9-22(20)29-23)8-6-12-26-15-13-25(3)14-16-26/h4-5,7-11,17H,6,12-16H2,1-3H3/b19-8+

InChI key: InChIKey=GFBKORZTTCHDGY-UHFFFAOYSA-N

SMILES: C(CCN1CCN(C)CC1)=C2C=3C(SC=4C2=CC=CC4)=CC=C(S(N(C)C)(=O)=O)C3

Sinonimi:

• 2-(Dimethylsulfamoyl)-[9-(4-methyl-1-piperazinyl)propylidene]thioxanthene
• Cp 12252-1
• N,N-Dimethyl-9-[3-(4-methyl-1-piperazinyl)propylidene]-9H-thioxanthene-2-sulfonamide
• N,N-Dimethyl-9-[3-(4-methyl-1-piperazinyl)propylidene]thioxanthene-2-sulfonamide
• N,N-Dimethyl-9-[3-(4-methylpiperazin-1-yl)propyliden]-9H-thioxanthen-2-sulfonamid
• N,N-dimethyl-9-[3-(4-methylpiperazin-1-yl)propylidene]-9H-thioxanthene-2-sulphonamide
• N,N-dimethyl-9-[3-(4-methylpiperazine-1-yl)propylidene]-9H-thioxanthene-2-sulfonamide
• N,N-dimetil-9-[3-(4-metilpiperazin-1-il)propiliden]-9H-tioxanteno-2-sulfonamida
• Navan
• Navane
• Navaron
• Nsc 108165
• Orbinamon
• P 4657B
• Thiothixene
• Thioxanthene-2-sulfonamide, N,N-dimethyl-9-[3-(4-methyl-1-piperazinyl)propylidene]-
• Thixit
• Tiotixene
• cis-Thiothixene
• 9H-Thioxanthene-2-sulfonamide, N,N-dimethyl-9-[3-(4-methyl-1-piperazinyl)propylidene]-
• N,N-dimethyl-9-[3-(4-methylpiperazin-1-yl)propylidene]thioxanthene-2-sulfonamide
• (9E)-N,N-dimethyl-9-[3-(4-methylpiperazin-1-yl)propylidene]-9H-thioxanthene-2-sulfonamide
• N,N-dimethyl-9-[3-(4-methylpiperazin-1-yl)propylidene]-9H-thioxanthene-2-sulfonamide
• n,n-dimethyl-9-(3-(4-methyl-1-piperazinyl)propylidene)thiaxanthene-2-sulfona
• N,N-Dimethyl-9-(3-(4-methyl-1-piperazinyl)propylidene)thiaxanthene-2-sulfonamide
• 9H-Thioxanthene-2-sulfonamide, N,N-dimethyl-9-(3-(4-methyl-1-piperazinyl)propylidene)-, (Z)-
• 9h-thioxanthene-2-sulfonamide,n,n-dimethyl-9-(3-(4-methyl-1-piperazinyl)propyl
• n,n-dimethyl-9-(3-(4-methyl-1-piperazinyl)propylidene)thioxanthene-2-sulfona
• TIOTIXENE/THIOTHIXENE
• THIOTHIXENE,USP
• THIOTHIXENE MEETS USP TESTING SPECIFICA
• CP-12,252-1 base
• (Z)-N,N-dimethyl-9-(3-(4-methylpiperazin-1-yl)
• Thiothixine
• n,n-dimethyl-9-(3-(4-methyl-1-piperazinyl)propylidene)thioxanthene-2-sulfonami
• Thiothixene (Navane)
• (9Z)-N,N-Dimethyl-9-[3-(4-methyl-1-piperazinyl)propylidene]-9H-thioxanthene-2-sulfonamide
• cp12252-1

Thiothixene

CAS: 5591-45-7

Thiothixene has a wide range of applications in life science related research.

Formula: C₂₃H₂₉N₃O₂S₂

Colore e forma: Solid

Peso molecolare: 443.62

Ref: TM-T38200

Thiothixene-13C-d3

CAS: 5591-45-7

Formula: C₂₂₁₃CH₂₆D₃N₃O₂S₂

Peso molecolare: 447.63

Ref: 4Z-T-228002

(Z)-Thiothixene-d8

Prodotto controllato

CAS: 5591-45-7

Formula: C₂₃H₂₁D₈N₃O₂S₂

Colore e forma: Neat

Peso molecolare: 451.67

Ref: TR-T375283

Thiothixene-d8

Prodotto controllato

CAS: 5591-45-7

Thiothixene is a drug used to treat schizophrenia that belongs to the class of antipsychotics. It is a serotonin reuptake inhibitor and has been shown to be effective in treating chronic schizophrenia. Thiothixene also has anti-nervous system activities, which are due to its ability to inhibit the release of acetylcholine. This drug binds with high affinity to α7 nicotinic acetylcholine receptors and blocks the flow of chloride ions across the cell membrane, leading to an accumulation of negatively charged ions inside the cell. The drug also inhibits mineralization and has been shown to prevent structural heart disease in animals. Thiothixene may be harmful if taken with pyrite or salinity because it can cause oxidative damage in redox potential environments. The drug can also cause plasma mass spectrometry profiles that show changes in carboniferous content, which may be related to the development of nervous system diseases.

Formula: C₂₃H₂₁D₈N₃O₂S₂

Purezza: Min. 95%

Peso molecolare: 451.67 g/mol

Ref: 3D-FAA59145