CAS 56-49-5

3-Metilcolantrene

Descrizione:

3-Metilcolantrene è un idrocarburo aromatico policiclico (PAH) caratterizzato dalla sua struttura complessa, che include più anelli aromatici fusi. È un derivato del colantrene, con un gruppo metile attaccato alla terza posizione. Questo composto è noto per il suo ruolo significativo nella ricerca sul cancro, in particolare negli studi relativi alla carcinogenesi, poiché è un potente mutageno e ha dimostrato di indurre tumori negli animali da laboratorio. 3-Metilcolantrene è tipicamente un solido a temperatura ambiente ed è insolubile in acqua ma solubile in solventi organici come benzene e cloroformio. La sua formula chimica è C18H14 e presenta una fluorescenza caratteristica sotto luce ultravioletta. Il composto è anche noto per la sua stabilità e persistenza nell'ambiente, sollevando preoccupazioni riguardo ai suoi potenziali effetti sulla salute e impatto ecologico. A causa delle sue proprietà cancerogene, la manipolazione di 3-Metilcolantrene richiede rigorose precauzioni di sicurezza in ambienti di laboratorio.

Formula: C₂₁H₁₆

InChI: InChI=1/C21H16/c1-13-11-15-6-4-7-16-12-19-17-8-3-2-5-14(17)9-10-18(19)20(13)21(15)16/h2-10,12-13H,11H2,1H3

InChI key: InChIKey=PPQNQXQZIWHJRB-UHFFFAOYSA-N

SMILES: CC1=C2C3=C(C=4C(C=C3C=C1)=C5C(=CC4)C=CC=C5)CC2

Sinonimi:

• 1,2-Dihydro-3-methylbenz(j)aceanthrylene
• 1-Methyl-1,2-Dihydrocyclopenta[Ij]Tetraphene
• 20-Mc
• 20-Methylcholanthrene
• 3-Mc
• 3-Mch
• 3-MeCA
• 3-Methoxycholanthrene
• 3-Methyl-1,2-Dihydrocyclopenta[Ij]Tetraphene
• 3-Methyl-1,2-dihydrobenzo[j]aceanthrylene
• 3-Methyl-I,J-cyclopentabenz(a)anthracene
• 3-Methylbenz(j)aceanthrene
• 3-Methylchloanthrene
• 3-Methylcholanthren
• 3-Methylcholanthren [German]
• 3-Methylcyclopentabenzophenanthrene
• 3-Metilcolantreno
• Ai3-50462
• Benz(j)aceanthrylene, 1,2-dihydro-3-methyl-
• Brn 1913890
• Ccris 386
• Cholanthrene, 3-methyl-
• Hsdb 2942
• MCA
• Methylcholanthrene
• Nsc 21970
• RCRA waste no. U157
• RCRA waste number U157
• 4-05-00-02648 (Beilstein Handbook Reference)
• 1,2-dihydro-3-methyl-benz(j)aceanthrylen
• 20-methylchlolanthrene
• 3-METHYLCHOLANTHRENE
• 3-methyl-cholanthren
• 3-Methylcholanthrene-(20)
• 3-MCA

3-Methylcholanthrene

CAS: 56-49-5

Formula: C₂₁H₁₆

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 268.3517

Ref: IN-DA00DEP5

3-Methylcholanthrene

CAS: 56-49-5

3-Methylcholanthrene is a carcinogenic polycyclic hydrocarbon formed during combustion, accumulates in prostate tissue, and serves as a prostate cancer model.

Formula: C₂₁H₁₆

Purezza: 99.49%

Peso molecolare: 268.35

Ref: TM-T80664

3-Methyl-1,2-dihydrocyclopenta[ij]tetraphene

CAS: 56-49-5

3-Methyl-1,2-dihydrocyclopenta[ij]tetraphene

Purezza: 98%

Peso molecolare: 268.36g/mol

Ref: 54-OR1067137

EPA Method 610 Additions PAH Mixture 446 1000 µg/mL in Dichloromethane

Prodotto controllato

CAS: 189-55-9, 189-64-0, 192-65-4, 194-59-2, 205-82-3, 224-42-0, 226-36-8, 56-49-5

Colore e forma: Mixture

Ref: 04-A50000446DI

EPA Method 610 Additions PAH Mixture 445 5-100 µg/mL in Acetonitrile

CAS: 120-12-7, 129-00-0, 189-55-9, 189-64-0, 191-24-2, 192-65-4, 193-39-5, 194-59-2, 205-82-3, 205-99-2, 206-44-0, 207-08-9, 208-96-8, 218-01-9, 224-42-0, 226-36-8, 50-32-8, 53-70-3, 56-49-5, 56-55-3, 83-32-9, 85-01-8, 86-73-7, 91-20-3

Colore e forma: Mixture

Ref: 04-A50000445AL

EPA Method 8270 App. IX Calibration Mixture 602 1000 µg/mL in Dichloromethane

Prodotto controllato

CAS: 100-51-6, 100-75-4, 10595-95-6, 108-39-4, 109-06-8, 110-86-1, 120-58-1, 122-39-4, 134-32-7, 1888-71-7, 53-96-3, 55-18-5, 56-49-5, 56-57-5, 57-97-6, 58-90-2, 59-89-2, 60-11-7, 608-93-5, 62-44-2, 62-53-3, 76-01-7, 82-68-8, 87-65-0, 88-85-7, 91-59-8, 92-67-1, 924-16-3, 930-55-2, 94-59-7, 95-53-4, 95-94-3, 98-86-2, 99-35-4, 99-55-8, 99-65-0

Colore e forma: Mixture

Ref: 04-A50000602DI

3-Methylcholanthrene

Prodotto controllato

CAS: 56-49-5

Formula: C₂₁H₁₆

Colore e forma: Neat

Peso molecolare: 268.35

Ref: 04-C20850000

EPA Method 8270 Appendix IX Mixture 2 1000 µg/mL in Dichloromethane

Prodotto controllato

CAS: 100-52-7, 101-84-8, 105-60-2, 120-58-1, 123-91-1, 130-15-4, 140-57-8, 143-50-0, 1888-71-7, 224-42-0, 2303-16-4, 23950-58-5, 465-73-6, 510-15-6, 56-49-5, 56-57-5, 57-97-6, 608-93-5, 62-44-2, 62-50-0, 66-27-3, 76-01-7, 82-68-8, 87-65-0, 90-13-1, 92-52-4, 94-59-7, 95-94-3, 97-63-2, 98-86-2, 99-35-4

Formula: C₆H₂Cl₄

Colore e forma: Mixture

Peso molecolare: 215.89

Ref: 04-GA09000445DI

EPA Method 8270 Calibration by Class Mixture 2000 µg/mL in Dichloromethane

Prodotto controllato

CAS: 120-12-7, 129-00-0, 191-24-2, 193-39-5, 205-99-2, 206-44-0, 207-08-9, 208-96-8, 218-01-9, 50-32-8, 53-70-3, 56-49-5, 56-55-3, 83-32-9, 85-01-8, 86-73-7, 90-12-0, 91-20-3, 91-57-6

Formula: C₁₁H₁₀

Colore e forma: Mixture

Peso molecolare: 142.20

Ref: 04-GA09000441DI

3-Methylcholanthrene

Prodotto controllato

CAS: 56-49-5

Applications A carcinogen.

Formula: C₂₁H₁₆

Colore e forma: Yellow To Dark Yellow

Peso molecolare: 268.35

Ref: TR-M294460

3-Methylcholanthrene

Prodotto controllato

CAS: 56-49-5

3-Methylcholanthrene (3MC) is a mutagen that has been shown to be carcinogenic in animals. It binds to the DNA, which causes breaks in the DNA strands and leads to mutations. 3MC is also an inducer of tumor formation and is active against murine sarcoma virus. 3MC has been shown to induce enzyme activities in vitro and can be used to study the effects of enzyme inhibitors on enzymatic activity. 3MC has been shown to have potent inducers of tumor formation, especially when administered at high doses. The potent tumor-promoting effect may be due to its ability to bind with DNA and inhibit the synthesis of RNA, leading to increased proliferation of hepatocyte-like cells.

Formula: C₂₁H₁₆

Purezza: Min. 95%

Colore e forma: Yellow Clear Liquid

Peso molecolare: 268.35 g/mol

Ref: 3D-FM25802