CAS 56-54-2

Chinidina

Descrizione:

Chinidina è un alcaloide derivato dalla corteccia dell'albero della china ed è utilizzato principalmente come farmaco antiaritmico. È uno stereoisomero della chinina e presenta una struttura complessa caratterizzata da un sistema biciclico contenente un anello di quiniclidina. Chinidina è noto per la sua capacità di bloccare i canali sodio, il che aiuta a stabilizzare il ritmo cardiaco ed è efficace nel trattamento di vari tipi di aritmie. La sostanza viene tipicamente somministrata nelle sue forme di sale solfato o gluconato, migliorando la sua solubilità e biodisponibilità. Chinidina ha un punto di fusione moderato-alto ed è solubile in acqua, alcol e cloroformio, ma meno in etere. I suoi effetti farmacologici possono includere effetti collaterali come disturbi gastrointestinali e potenziale cardiotossicità, richiedendo un attento monitoraggio durante l'uso. Inoltre, Chinidina può interagire con altri farmaci, influenzando il loro metabolismo e la loro efficacia. In generale, Chinidina rimane un composto importante nel campo della cardiologia, nonostante l'emergere di nuovi agenti antiaritmici.

Formula: C₂₀H₂₄N₂O₂

InChI: InChI=1/C20H24N2O2/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18/h3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3/p+1/t13-,14-,19-,20-/m0/s1

InChI key: InChIKey=LOUPRKONTZGTKE-LHHVKLHASA-N

SMILES: [C@H](O)(C=1C2=C(C=CC(OC)=C2)N=CC1)[C@@]3([N@@]4C[C@H](C=C)[C@](C3)(CC4)[H])[H]

Sinonimi:

• (+)-Quindine
• (4beta,8alpha,9S)-9-hydroxy-6'-methoxycinchonan-1-ium
• (4beta,9S)-9-hydroxy-6'-methoxycinchonan-1-ium
• (8R,9S)-Quinidine
• (8alpha,9S)-9-hydroxy-6'-methoxycinchonan-1-ium
• (9S)-6'-methoxycinchonan-1-ium-9-ol
• (9S)-6'-methoxycinchonan-9-ol
• 6-Methoxy-α-(5-vinyl-2-quinuclidinyl)-4-quinolinemethanol
• Chinidin
• Cin-quin
• Cinchonan-9-ol, 6'-methoxy-, (9S)-
• Conchinin
• Conchinine
• Conquinine
• Kinidin
• Pitayin
• Pitayine
• Quinidina
• Quinidine free base
• β-Quinidine
• β-Quinine
• Quinidine
• 6-Methoxy-alpha-(5-vinyl-2-quinuclidinyl)-4-quinolinemethanol
• 6'-Methoxycinchonan-9-ol
• beta-Quinidine
• 2-Quinuclidinemethanol, alpha-(6-methoxy-4-quinolyl)-5-vinyl-
• (95)-cinchonan-9-0
• 6-METHOXY-A-(5-VINYL-2-QUINUCLIDINYL)-4-QUINOLINE-METHANOL
• (8R,9S)-6'-Methoxycinchonan-9-ol
• alpha-(6-Methoxy-4-quinolyl)-5-vinyl-2-quinuclidinemethanol

Quinidine

CAS: 56-54-2

Formula: C₂₀H₂₄N₂O₂

Purezza: >85.0%(HPLC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 324.42

Ref: 3B-Q0006

(+)-Quinidine

CAS: 56-54-2

(+)-Quinidine is used to treat or prevent many types of irregular heartbeats (heart arrhythmias such as atrial fibrillation). It may also be used to treat malaria. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label in

Formula: C₂₀H₂₄N₂O₂

Colore e forma: Powder or crystalline powder, White to cream to yellow to brown

Peso molecolare: 324.42

Ref: 02-A12559

Quinidine

CAS: 56-54-2

Quinidine analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.

Formula: C₂₀H₂₄N₂O₂

Purezza: (HPLC) ≥90%

Colore e forma: Powder

Peso molecolare: 324.42

Ref: 11-0611

(9S)-6'-Methoxycinchonan-9-ol

CAS: 56-54-2

Formula: C₂₀H₂₄N₂O₂

Purezza: 85%

Colore e forma: Solid

Peso molecolare: 324.4168

Ref: IN-DA0035K6

Quinidine

CAS: 56-54-2

Quinidine

Purezza: ≥95%

Peso molecolare: 324.42g/mol

Ref: 54-BUP16485

Quinidine

CAS: 56-54-2

Formula: C₂₀H₂₄N₂O₂

Peso molecolare: 324.42

Ref: 4Z-Q-049

Quinidine

CAS: 56-54-2

Formula: C₂₀H₂₄N₂O₂

Purezza: (Titration) 98.0 - 102.0 % (inc. dihydroquinidine)

Colore e forma: White to off-white pale beige powder or crystals

Peso molecolare: 324.42

Ref: 7W-GE1634

Quinidine

CAS: 56-54-2

Colore e forma: Neat

Ref: 61-FOR1523.01

Quinidine

CAS: 56-54-2

Formula: C₂₀H₂₄N₂O₂

Purezza: 95%~99%

Peso molecolare: 324.424

Ref: BP-BP4185

(+)-Quinidine

CAS: 56-54-2

(+)-Quinidine

Formula: C₂₀H₂₄N₂O₂

Purezza: 97%

Colore e forma: white solid

Peso molecolare: 324.42g/mol

Ref: 54-BIB1110

Quinidine

CAS: 56-54-2

Quinidine is a stereoisomer of the antimalarial agent quinine and a class Ia antiarrhythmic agent. for the treatment of abnormal heart rhythms and also malaria.

Formula: C₂₀H₂₄N₂O₂

Purezza: 97.03% - 99.99%

Colore e forma: Crystals With 2 5 Mol Water Of Crystallization; Crystals From Dilute Alcohol Physical Description Crystals Or White Powder (Ntp 1992)

Peso molecolare: 324.42

Ref: TM-T7938

(+)-quinidine

CAS: 56-54-2

Cinchona alkaloid

Formula: C₂₀H₂₄N₂O₂

Purezza: ≥ 85.0 % (HPLC)

Colore e forma: Powder

Peso molecolare: 324.42

Ref: 5G-80964

Quinidine (>85%%)

Prodotto controllato

CAS: 56-54-2

Formula: C₂₀H₂₄N₂O₂

Purezza: >85%%

Colore e forma: White To Off-White

Peso molecolare: 324.42

Ref: TR-Q685070

Quinidine

Prodotto controllato

CAS: 56-54-2

Applications A dextrorotatory stereoisomer of Quinine. Antiarrhythmic (class IA). Antimalarial.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Loutfy, M.A., et al.: Anal. Profiles Drug Subs., 12, 483 (1983), Mason, J. W., et al.: Ann. N. Y. Acad. Sci., 432, 162 (1984),

Formula: C₂₀H₂₄N₂O₂

Colore e forma: White To Off-White

Peso molecolare: 324.42

Ref: TR-Q685000

(1S)-(6-Methoxyquinolin-4-yl)((2R,4S,5R)-5-vinylquinuclidin-2-yl)methanol

CAS: 56-54-2

Formula: C₂₀H₂₄N₂O₂

Purezza: ≥85%

Colore e forma: Solid, Crystalline or Powder

Peso molecolare: 324.424

Ref: 10-F079244

(S)-7-Benzyloxy Warfarin Quinidine Salt

Prodotto controllato

CAS: 30992-69-9, 56-54-2

Formula: C₂₆H₂₂O₅·C₂₀H₂₄N₂O₂

Colore e forma: Neat

Peso molecolare: 738.867

Ref: TR-B288540

6-Methoxy-α-(5-vinyl-2-quinuclidinyl)-4-quinolinemethanol

CAS: 56-54-2

6-Methoxy-α-(5-vinyl-2-quinuclidinyl)-4-quinolinemethanol is an antimalarial agent, derived from synthetic processes aimed at enhancing the activity of quinoline-based compounds. This compound acts by interacting with the heme moieties in the parasitic digestive vacuole, disrupting the detoxification of heme products, which is essential for parasite survival. By interfering with this process, the compound effectively causes toxic heme accumulation, leading to the death of the Plasmodium species responsible for malaria.

Formula: C₂₀H₂₄N₂O₂

Purezza: 80%

Peso molecolare: 324.42 g/mol

Ref: 3D-FM27376

Quinine EP Impurity A

CAS: 56-54-2

Formula: C₂₀H₂₄N₂O₂

Peso molecolare: 324.42

Ref: ST-EA-CP-Q3001