CAS 5611-51-8

Triamcinolone esacetonide

Descrizione:

Triamcinolone esacetonide è un corticosteroide sintetico con proprietà anti-infiammatorie e immunosoppressive. È derivato dalla triamcinolone, un glucocorticoide ben noto, ed è caratterizzato dalla sua esterificazione esacetonidica, che ne aumenta la lipofilia e prolunga la sua azione. Questo composto viene tipicamente somministrato tramite iniezione intramuscolare o come iniezione intra-articolare per il trattamento di varie condizioni infiammatorie, inclusa l'artrite e altri disturbi articolari. Triamcinolone esacetonide mostra un'alta affinità per i recettori dei glucocorticoidi, portando alla modulazione dell'espressione genica e alla successiva riduzione dei mediatori infiammatori. I suoi effetti farmacologici includono l'inibizione dell'infiltrazione dei leucociti nel sito di infiammazione, la soppressione delle risposte immunitarie umorali e la stabilizzazione delle membrane lisosomiali. Sebbene sia efficace nella gestione dell'infiammazione, può anche avere effetti collaterali, come la potenziale soppressione surrenalica e alterazioni metaboliche, in particolare con l'uso prolungato. Come con tutti i corticosteroidi, è essenziale considerare attentamente il dosaggio e la durata della terapia per minimizzare gli effetti avversi massimizzando i benefici terapeutici.

Formula: C₃₀H₄₁FO₇

InChI: InChI=1/C30H41FO7/c1-25(2,3)15-24(35)36-16-22(34)30-23(37-26(4,5)38-30)13-20-19-9-8-17-12-18(32)10-11-27(17,6)29(19,31)21(33)14-28(20,30)7/h10-12,19-21,23,33H,8-9,13-16H2,1-7H3/t19-,20-,21-,23+,27-,28-,29-,30+/m0/s1

InChI key: InChIKey=TZIZWYVVGLXXFV-FLRHRWPCSA-N

SMILES: C(COC(CC(C)(C)C)=O)(=O)[C@]12[C@]3(C)[C@@](C[C@]1(OC(C)(C)O2)[H])([C@]4([C@](F)([C@@H](O)C3)[C@]5(C)C(CC4)=CC(=O)C=C5)[H])[H]

Sinonimi:

• (11β,16α)-21-(3,3-Dimethyl-1-oxobutoxy)-9-fluoro-11-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione
• 2-[(4aS,4bR,5S,6aS,6bS,9aR,10aS,10bS)-4b-fluoro-5-hydroxy-4a,6a,8,8-tetramethyl-2-oxo-2,4a,4b,5,6,6a,9a,10,10a,10b,11,12-dodecahydro-6bH-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-6b-yl]-2-oxoethyl 3,3-dimethylbutanoate
• Aristospan
• Butyric acid, 3,3-dimethyl-, 21-ester with 9-fluoro-11β,16α,17,21-tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with acetone
• Cl 34433
• Hexatrione
• Lederlon
• Lederspan
• Pregna-1,4-diene-3,20-dione, 21-(3,3-dimethyl-1-oxobutoxy)-9-fluoro-11-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]-, (11β,16α)-
• Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,16α,17,21-tetrahydroxy-, cyclic 16,17-acetal with acetone, 21-(3,3-dimethylbutyrate)
• Tatba
• Triamcinolone Hexaacetonide
• Triamcinolone acetonide 21-tert-butylacetate
• Triamcinolone acetonide tert-butyl acetate
• Triamcinolone Hexacetonide (1679008)
• C08185
• 21-(3,3-Dimethyl-1-oxobutoxy)-9-fluoro-11β-hydroxy-16α,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione
• TRIAMCINOLONE HEXACETONIDE
• cl34433
• Triamcinolone hexatonide
• Triamcinolone hexacetonide CRS
• Triamcinolone Hexacetonide (200 mg)
• lic16,17-acetalwithacetone,21-(3,3-dimethylbutyrate)
• 4-diene-3,20-dione,9-fluoro-11-beta,16-alpha,17,21-tetrahydroxy-pregna-cyc
• 9-Fluoro-11β,21-dihydroxy-16α,17-(isopropylidenebisoxy)pregna-1,4-diene-3,20-dione 21-(3,3-dimethylbutyrate)

Triamcinolone Hexacetonide

CAS: 5611-51-8

Colore e forma: Neat

Ref: 61-FOR0306.00

TRIAMCINOLONE HEXACETONIDE CRS

CAS: 5611-51-8

TRIAMCINOLONE HEXACETONIDE CRS

Formula: C₃₀H₄₁FO₇

Colore e forma: Crystalline Powder. White. Powder.

Peso molecolare: 532.6407

Ref: 41-T1950000

TRIAMCINOLONE HEXACETONIDE FOR SYSTEM SUITABILITY CRS

CAS: 5611-51-8

TRIAMCINOLONE HEXACETONIDE FOR SYSTEM SUITABILITY CRS

Formula: C₃₀H₄₁FO₇

Colore e forma: Crystalline Powder. White. Powder.

Peso molecolare: 532.6407

Ref: 41-Y0001843

Triamcinolone hexacetonide

CAS: 5611-51-8

Triamcinolone hexacetonide

Formula: C₃₀H₄₁FO₇

Purezza: 99.6%

Colore e forma: White Crystalline Powder

Peso molecolare: 532.28363

Ref: 47-680

Triamcinolone Hexacetonide

CAS: 5611-51-8

Halogenated derivatives of adrenal cortical hormones

Formula: C₃₀H₄₁FO₇

Colore e forma: Powder

Peso molecolare: 532.28363

Ref: 45-1679008

Pregna-1,4-diene-3,20-dione,21-(3,3-dimethyl-1-oxobutoxy)-9-fluoro-11-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]-, (11b,16a)-

CAS: 5611-51-8

Formula: C₃₀H₄₁FO₇

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 532.6407

Ref: IN-DA01CCNK

Triamcinolone hexacetonide

CAS: 5611-51-8

Triamcinolone hexacetonide

Purezza: ≥98%

Peso molecolare: 532.64g/mol

Ref: 54-BUP09266

Triamcinolone Hexacetonide

Prodotto controllato

CAS: 5611-51-8

Formula: C₃₀H₄₁FO₇

Colore e forma: Neat

Peso molecolare: 532.64

Ref: 86-MM0306.00

Triamcinolone hexacetonide

CAS: 5611-51-8

Formula: C₃₀H₄₁FO₇

Peso molecolare: 532.65

Ref: 4Z-T-5326

Triamcinolone Hexacetonide-d9

CAS: 5611-51-8

Formula: C₃₀H₃₂D₉FO₇

Peso molecolare: 541.70

Ref: 4Z-T-5332

Triamcinolone Hexacetonide

Prodotto controllato

CAS: 5611-51-8

Applications Triamcinolone Hexacetonide is the Intra-articular glucocorticoid treatment for rheumatoid arthritis.
References Abd-El-Barr, M.M., et al.: J. Ocul. Pharmacol. Ther., 24, 197 (2007); Eberhard, B.A., et al.: J. Rheumatol., 31, 2507 (2004);

Formula: C₃₀H₄₁FO₇

Colore e forma: White

Peso molecolare: 532.64

Ref: TR-T767190

Triamcinolone hexacetonide

CAS: 5611-51-8

Triamcinolone hexacetonide, an exogenous synthetic corticosteroid, is a GR agonist used in the study of auto-reactive pericarditis and diabetic macular edema.

Formula: C₃₀H₄₁FO₇

Purezza: 99.57%

Colore e forma: Solid

Peso molecolare: 532.64

Ref: TM-T17162

Triamcinolone Hexacetonide-13CD3

Prodotto controllato

CAS: 5611-51-8

Formula: C₂₉CH₃₈D₃FO₇

Colore e forma: Neat

Peso molecolare: 536.65

Ref: TR-T767194

Triamcinolone Hexacetonide-d9

Prodotto controllato

CAS: 5611-51-8

Applications Triamcinolone Hexacetonide-d9 is the labelled form of Triamcinolone Hexacetonide (T767190). Triamcinolone Hexacetonide is the Intra-articular glucocorticoid treatment for rheumatoid arthritis.
References Abd-El-Barr, M.M., et al.: J. Ocul. Pharmacol. Ther., 24, 197 (2007); Eberhard, B.A., et al.: J. Rheumatol., 31, 2507 (2004)

Formula: C₃₀D₉H₃₂FO₇

Colore e forma: Neat

Peso molecolare: 541.696

Ref: TR-T767192

Triamcinolone hexacetonide

CAS: 5611-51-8

Triamcinolone hexacetonide is a nonsteroidal anti-inflammatory drug that is used to treat arthritis. It is a prodrug that is hydrolyzed in vivo to triamcinolone acetonide, its active form. Triamcinolone hexacetonide has been shown to be effective against arthritis and other inflammatory diseases of the joints. It inhibits the production of prostaglandins by blocking the release of arachidonic acid from membrane phospholipids. This reduces pain and inflammation with minimal side effects. The drug also has immunosuppressive properties, which may be due to its ability to inhibit toll-like receptor signaling pathways and response elements involved in the immune response. Triamcinolone hexacetonide can be administered orally or intra-articularly for treatment of inflammation.

Formula: C₃₀H₄₁FO₇

Purezza: Min. 95%

Peso molecolare: 532.64 g/mol

Ref: 3D-FAA61151