CAS 56287-74-2

Afloqualone

Descrizione:

Afloqualone è un composto sintetico classificato come un derivato della quinazolinone, noto principalmente per le sue proprietà miorilassanti e ansiolitiche. È caratterizzato dalla sua capacità di agire come un depressore del sistema nervoso centrale, il che lo rende efficace nel trattamento di condizioni come spasmi muscolari e ansia. La struttura chimica di Afloqualone include un anello di quinazolina, che contribuisce alla sua attività farmacologica. Viene tipicamente somministrato per via orale ed è stato studiato per i suoi potenziali effetti terapeutici, sebbene il suo uso possa essere limitato a causa di effetti collaterali e dello stato normativo in vari paesi. Il composto ha una moderata lipofilia, che influisce sulla sua assorbimento e distribuzione nei sistemi biologici. Inoltre, il meccanismo d'azione di Afloqualone coinvolge la modulazione dei sistemi di neurotrasmettitori, in particolare le vie GABAergiche, che sono cruciali per i suoi effetti sedativi e miorilassanti. Come per molti farmaci, è essenziale considerare attentamente il dosaggio e le potenziali interazioni con altri farmaci per un uso sicuro.

Formula:C₁₆H₁₄FN₃O

InChI:InChI=1/C16H14FN3O/c1-10-4-2-3-5-14(10)20-15(9-17)19-13-7-6-11(18)8-12(13)16(20)21/h2-8H,9,18H2,1H3

InChI key:InChIKey=VDOSWXIDETXFET-UHFFFAOYSA-N

SMILES:C(F)C=1N(C(=O)C=2C(N1)=CC=C(N)C2)C3=C(C)C=CC=C3

Sinonimi:

(2-Tolyl)-3H-quinazolin-4-one
4(3H)-quinazolinone, 6-amino-2-(fluoromethyl)-3-(2-methylphenyl)-
6-Amino-2-(fluoromethyl)-3-(2-methylphenyl)-4(3H)-quinazolinone
6-Amino-2-(fluoromethyl)-3-(2-methylphenyl)quinazolin-4(3H)-one
6-Amino-2-Fluoromethyl-3-
Aroft
Arofuto
H 495
Hq 495
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
Afloqualone
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-fluoromethyl-3-(o-tolyl)-quinazolin-4(3H)-one
6-amino-2-(fluoromethyl)-3-(2-methylphenyl)-4(3h)-quinazolinon
6-Amino-2-Fluoromethyl-3-(2-Tolyl)-3H-quinazolin-4-one
6-Amino-2-Fluoromethyl-3-
(2-Tolyl)-3H-quinazolin-4-one
6-amino-2-(fluoromethyl)-3-(2-methylphenyl)-quinazolin-4-one
6-amino-2-fluoromethyl-3-(o-tolyl)-4(3h)-quinazolinon
Vedi altri sinonimi

Purezza (%)

100

4 prodotti.

+ Info
4(3H)-Quinazolinone, 6-amino-2-(fluoromethyl)-3-(2-methylphenyl)-
CAS:
- 56287-74-2
Formula:C₁₆H₁₄FN₃O
Purezza:98%
Colore e forma:Solid
Peso molecolare:283.3003
Ref: IN-DA00IA22
100mg
140,00€
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250mg
202,00€
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500mg
322,00€
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Afloqualone
CAS:
- 56287-74-2
Afloqualone (HQ-495) is a GABA Receptor agonist with sedative and muscle-relaxant properties.
Formula:C₁₆H₁₄FN₃O
Purezza:99.72%
Colore e forma:Solid
Peso molecolare:283.3
Ref: TM-T4993
+ Info
Afloqualone
CAS:
- 56287-74-2
Applications Afloqualone acts as a muscle relaxant in humans and may be used in the treatment of muscle spasms affecting rheumatoid arthritis. References Farkas, S. et al.: J. Pharm. Toxicol. Meth., 52, 264 (2005); Yun, H. et al.: Talanta, 73, 635 (2007); 
Formula:C₁₆H₁₄FN₃O
Colore e forma:White To Off-White
Peso molecolare:283.30
Ref: TR-A357700
250mg
171,00€
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6-Amino-2-(fluoromethyl)-3-(2-methylphenyl)-quinazolin-4-one
Prodotto controllatoSi prega di notare che in alcuni Paesi questo è un prodotto controllato e deve essere trattato in conformità alle normative vigenti. Si tenga presente che ciò potrebbe comportare spese e documentazione aggiuntive.
CAS:
- 56287-74-2
6-Amino-2-(fluoromethyl)-3-(2-methylphenyl)-quinazolin-4-one is a potent inhibitor of the enzyme dihydrofolate reductase, which is required for the synthesis of DNA and other macromolecules. It has been shown to inhibit the growth of cutaneous lesions in mice and rats. The compound has also been found to be effective against renal lesions (caused by cevimeline hydrochloride) in rats. The compound has a high inhibitory dose as it binds tightly with divalent metal ions such as magnesium, calcium, and zinc. This property may result in its use as an anticancer drug. 6-Amino-2-(fluoromethyl)-3-(2-methylphenyl)-quinazolin-4-one is soluble in water and polymeric matrices and can be administered orally or intravenously.
Formula:C₁₆H₁₄FN₃O
Purezza:Min. 95%
Colore e forma:White Powder
Peso molecolare:283.3 g/mol
Ref: 3D-FA29178
1g
713,00€
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50mg
135,00€
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100mg
183,00€
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250mg
382,00€
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500mg
509,00€
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