CAS 56354-06-4

11-Nor-9-carbossi-Δ9-tetraidrocannabinolo

Descrizione:

11-Nor-9-carbossi-Δ9-tetraidrocannabinolo, comunemente noto come THC-COOH, è un metabolita del tetraidrocannabinolo (THC), il principale componente psicoattivo della cannabis. Questo composto è caratterizzato dal suo gruppo funzionale acido carbossilico, che lo distingue dal suo composto genitore, il THC. Il THC-COOH è tipicamente non psicoattivo ed è spesso utilizzato come biomarcatore nei test antidroga per indicare l'uso di cannabis, poiché può essere rilevato nelle urine per un periodo prolungato dopo il consumo. La sostanza è lipofila, consentendole di accumularsi nei tessuti adiposi, il che contribuisce alla sua presenza prolungata nel corpo. La sua struttura molecolare include un telaio biciclico tipico dei cannabinoidi e mostra un'alta affinità per i recettori cannabinoidi, sebbene con attività ridotta rispetto al THC. Il composto è di interesse in farmacologia e tossicologia, in particolare negli studi relativi al metabolismo della cannabis e agli effetti della cannabis sulla salute umana. Comprendere le sue caratteristiche è cruciale per interpretare i test antidroga e valutare le implicazioni dell'uso di cannabis.

Formula: C₂₁H₂₈O₄

InChI: InChI=1S/C21H28O4/c1-4-5-6-7-13-10-17(22)19-15-12-14(20(23)24)8-9-16(15)21(2,3)25-18(19)11-13/h10-12,15-16,22H,4-9H2,1-3H3,(H,23,24)/t15-,16-/m1/s1

InChI key: InChIKey=YOVRGSHRZRJTLZ-HZPDHXFCSA-N

SMILES: OC1=C2[C@]3([C@](C(C)(C)OC2=CC(CCCCC)=C1)(CCC(C(O)=O)=C3)[H])[H]

Sinonimi:

• (-)-11-Nor-9-carboxy-Δ⁹-THC
• (6aR,10aR)-1-hydroxy-6,6-dimethyl-3-pentyl-6a,7,8,10a-tetrahydro-6H-benzo[c]chromene-9-carboxylic acid
• (6aR,10aR)-6a,7,8,10a-Tetrahydro-1-hydroxy-6,6-dimethyl-3-pentyl-6H-dibenzo[b,d]pyran-9-carboxylic acid
• (±)11-Nor-9-carboxy-D9-THC
• 11-Nor-9-carboxy-⁹Δ-tetrahydrocannabinol
• 11-Nor-9-carboxy-THC
• 11-Nor-9-carboxy-Δ⁹-tetrahydrocannabinol
• 11-Nor-Δ⁹-tetrahydrocannabinol-9-carboxylic acid
• 11-nor-D9-tetrahydrocannabinol-9-*carboxylic acid
• 6H-Dibenzo[b,d]pyran-9-carboxylic acid, 6a,7,8,10a-tetrahydro-1-hydroxy-6,6-dimethyl-3-pentyl-, (6aR,10aR)-
• 6H-Dibenzo[b,d]pyran-9-carboxylic acid, 6a,7,8,10a-tetrahydro-1-hydroxy-6,6-dimethyl-3-pentyl-, (6aR-trans)-
• 9-Carboxy-11-nor-Δ⁹-tetrahydrocannabinol
• Tetrahydrocannabinol-7-oic acid
• l-11-Nor-9-carboxy-Δ⁹-tetrahydrocannabinol
• Δ¹-Tetrahydrocannabinol-7-oic acid
• Δ⁹-Tetrahydrocannabinol-11-oic acid
• Δ1-Tetrahydrocannabinol-7-oic acid

(-)-11-Nor-9-carboxy-δ9-THC 0.1 mg/ml in Methanol

Prodotto controllato

CAS: 56354-06-4

Colore e forma: Single Solution

Ref: 61-AMP1088.06-02

(-)-11-Nor-9-carboxy-δ9-THC 1.0 mg/ml in Methanol

Prodotto controllato

CAS: 56354-06-4

Colore e forma: Single Solution

Ref: 61-AMP1088.06-01

(-)-11-Nor-δ-9-THC carboxylic acid, 1mg/ml in Methanol

CAS: 56354-06-4

Colore e forma: Single Solution

Ref: LP-THC-316-1LM

(-)-11-Nor-δ-9-THC carboxylic acid, 0.1mg/ml in Methanol

CAS: 56354-06-4

Colore e forma: Single Solution

Ref: LP-THC-316-0.1LM

(-)-11-Nor-δ-9-THC carboxylic acid

CAS: 56354-06-4

Colore e forma: Neat

Ref: LP-THC-316-10

(-)-11-Nor-9-carboxy-delta9-THC solution

Prodotto controllato

CAS: 56354-06-4

11-Nor-9-carboxy-9-THC is a metabolite of Δ9-tetrahydrocannabinol that is produced by the action of glucuronide conjugate. It can be found in human serum, urine, and blood as well as wastewater treatment plants. 11-Nor-9-carboxy-9-THC can be used to detect cannabis use in humans. The concentration of 11-nor - 9 - carboxy - 9 - THC in urine is proportional to the amount of cannabis consumed and its metabolites are detectable for up to 8 days after last use. 11 - Nor - 9 - carboxy - 9 - THC can also be detected in saliva, but not as reliably as in urine or blood. 11 - Nor - 9 - carboxy - 9 - THC has been shown to have pharmacokinetic properties that are similar to those of Δ9 tetrahydrocannabinol and other cannabinoids. These properties include

Formula: C₂₁H₂₈O₄

Purezza: Min. 95%

Colore e forma: Clear Liquid

Peso molecolare: 344.45 g/mol

Ref: 3D-GCA35406