CAS 566-28-9

7-Cetocolesterolo

Descrizione:

7-Cetocolesterolo è un derivato ossidato del colesterolo, caratterizzato dalla presenza di un gruppo chetonico nella posizione C7 del nucleo steroideo. La sua formula molecolare è C27H46O e ha un peso molecolare di circa 402,65 g/mol. Questo composto è uno sterolo ed è noto per svolgere un ruolo in vari processi biologici, inclusi il segnale cellulare e la fluidità della membrana. 7-Cetocolesterolo è spesso studiato nel contesto delle sue potenziali implicazioni nella salute e nella malattia, in particolare in relazione all'aterosclerosi e ai disturbi neurodegenerativi, poiché può influenzare il metabolismo del colesterolo e la funzione cellulare. È anche riconosciuto per la sua capacità di indurre stress ossidativo e infiammazione nelle cellule. In termini di proprietà fisiche, 7-Cetocolesterolo è tipicamente un solido bianco o bianco sporco ed è solubile in solventi organici, ma ha una solubilità limitata in acqua. La sua reattività e le interazioni con altre biomolecole lo rendono un composto significativo sia in biochimica che in farmacologia.

Formula: C₂₇H₄₄O₂

InChI: InChI=1/C27H44O2/c1-17(2)7-6-8-18(3)21-9-10-22-25-23(12-14-27(21,22)5)26(4)13-11-20(28)15-19(26)16-24(25)29/h16-18,20-23,25,28H,6-15H2,1-5H3/t18?,20-,21+,22?,23?,25?,26-,27+/m0/s1

InChI key: InChIKey=YIKKMWSQVKJCOP-ABXCMAEBSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@]([C@]4(C)C(=CC3=O)C[C@@H](O)CC4)(CC1)[H])[H])(CC[C@@]2([C@@H](CCCC(C)C)C)[H])[H]

Sinonimi:

• (3Beta)-3-Hydroxycholest-5-En-7-One
• (3S,10R,13R,17R)-17-(1,5-dimethylhexyl)-3-hydroxy-10,13-dimethyl-1,2,3,4,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-7-one
• (3β)-3-Hydroxycholest-5-en-7-one
• (5Beta,7Alpha)-7-Hydroxy-3-Oxocholan-24-Oic Acid
• 3-Beta-Hydroxycholest-5-En-7-One
• 3β-Hydroxy-cholest-5-ene-7-one
• 3β-Hydroxycholest-5-en-7-one
• 5-cholesten-3B-ol-7-one
• 7-Ketocholesterol
• 7-Oxocholesterol
• Cholest-5-en-3β-ol-7-one
• Cholest-5-en-7-one, 3-hydroxy-, (3β)-
• Cholest-5-en-7-one, 3β-hydroxy-
• Sc 4722
• Δ5-Cholesten-3β-ol-7-one
• Δ⁵-Cholesten-3β-ol-7-one
• 5-CHOLESTEN-3BETA-OL-7-ONE
• 7-KetoC
• 5A-CHOLESTAN-3B-OL-7-ONE
• Ketocholesterol
• (3-beta)-cholest-5-en-7-on
• 7-Keto Cholesterol (~98%)
• 3BETA-HYDROXY-5-CHOLESTEN-7-ONE
• 3β-Hydroxy-5-cholesten-7-one, 7-Ketocholesterol
• 3-beta-hydroxy-cholest-5-en-7-on
• (3)-3-Hydroxycholest-5-en-7-one
• 3-hydroxy-5-cholestene-7-one
• 7-Ketocholesterolk
• Cholest-5-en-3-ol-7-one
• 7-Ketocholesterol (Solution)
• sc4722
• Cholesterol 7-Keto
• (3S,8S,9S,10R,13R,14S,17R)-17-[(1R)-1,5-dimethylhexyl]-3-hydroxy-10,13-dimethyl-1,2,3,4,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-7-one
• 7-oxo-cholestero
• Cholest-5-en-7-one, 3-hydroxy-, (3.beta.)-
• 3-Hydroxycholest-5-en-7-one
• 3β-hydroxy-5-cholesten-7-one
• (3S,8S,9S,10R,13R,14S,17R)-3-hydroxy-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-1,2,3,4,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-7-one
• 3-HYDROXY-5-CHOLESTENE-7-ONE;7-KETOCHOLESTEROL
• 3-hydroxy-10,13-dimethyl-17-(6-methylheptan-2-yl)-1,2,3,4,8,9,11,12,14,15,1 6,17-dodecahydrocyclopenta[a]phenanthren-7-one

7-Ketocholesterol

CAS: 566-28-9

Formula: C₂₇H₄₄O₂

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 400.6371

Ref: IN-DA00E9IF

7-Keto-Cholesterol

CAS: 566-28-9

Formula: C₂₇H₄₄O₂

Peso molecolare: 400.65

Ref: 4Z-C-5322

5-Cholesten-3Β-Ol-7-One

CAS: 566-28-9

5-Cholesten-3Β-Ol-7-One

Purezza: 98%

Peso molecolare: 400.64g/mol

Ref: 54-OR1022895

7-Ketocholesterol

CAS: 566-28-9

7-Ketocholesterol

Purezza: ≥95%

Peso molecolare: 400.65g/mol

Ref: 54-BUP06665

5-Cholesten-3β-ol-7-one

CAS: 566-28-9

Formula: C₂₇H₄₄O₂

Purezza: ≥ 98.0%

Colore e forma: White to off-white powder

Peso molecolare: 400.64

Ref: 7W-GL2633

7-Ketocholesterol

CAS: 566-28-9

Formula: C₂₇H₄₄O₂

Purezza: 95%~99%

Peso molecolare: 400.647

Ref: BP-BP4652

7-Ketocholesterol

CAS: 566-28-9

7-Ketocholesterol is a metabolite of Cholesterol

Formula: C₂₇H₄₄O₂

Purezza: 97.59% - 98.84%

Colore e forma: Solid

Peso molecolare: 400.65

Ref: TM-TN6715

7-Keto Cholesterol

Prodotto controllato

CAS: 566-28-9

Applications 7-Keto Cholesterol is a metabolite of Cholesterol.
References Wang, J., et al.: Biochemistry, 43, 1010 (2004), Lemaire-Ewing, S., et al.: Cell Biol. Toxicol., 21, 97 (2005), Fuda, H., et al.: J. Lipid Res., 48, 1343 ( 2007), Sasaki, H., et al.: Metabolism, 56, 357 (2007),

Formula: C₂₇H₄₄O₂

Purezza: ~98%

Colore e forma: Neat

Peso molecolare: 400.64

Ref: TR-K185050

7-Ketocholesterol

Prodotto controllato

CAS: 566-28-9

7-Ketocholesterol is a reactive molecule that can induce inflammation and has been shown to be associated with eye disorders. 7-Ketocholesterol is an intermediate in the biosynthesis of cholesterol and is converted to 7-keto-cholesterol by the enzyme HMG-CoA reductase. This compound has also been shown to be a potent inducer of autophagy, which is a process that degrades intracellular components. 7-Ketocholesterol binds to cell nuclei and alters their shape, which may lead to cancerous cell growth. For example, this molecule induces apoptosis in cultured human retinal pigment epithelial cells. The mechanism of action for 7-ketocholesterol involves mitochondrial membrane potential, ATP binding cassette transporters, and DNA polymerase chain reaction (PCR).

Formula: C₂₇H₄₄O₂

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 400.64 g/mol

Ref: 3D-FK24766

7-Ketocholesterol

CAS: 566-28-9

Formula: C₂₇H₄₄O₂

Peso molecolare: 400.6

Ref: ST-EA-CP-C71028