CAS 56796-39-5

Cefmetazolo sodico

Descrizione:

Cefmetazolo sodico è un antibiotico cefalosporinico semisintetico, classificato nel gruppo degli antibiotici beta-lattamici. È utilizzato principalmente per la sua attività antibatterica ad ampio spettro contro vari batteri Gram-positivi e Gram-negativi. Il cefmetazolo agisce inibendo la sintesi della parete cellulare batterica, portando alla lisi e alla morte cellulare. Il composto viene tipicamente somministrato per iniezione ed è efficace nel trattamento di infezioni come infezioni delle vie respiratorie, infezioni della pelle e infezioni del tratto urinario. È caratterizzato dalla sua stabilità contro alcune beta-lattamasi, il che ne aumenta l'efficacia contro ceppi batterici resistenti. Cefmetazolo sodico è generalmente ben tollerato, sebbene gli effetti collaterali potenziali possano includere reazioni allergiche, disturbi gastrointestinali e alterazioni nella coagulazione del sangue. La sua farmacocinetica prevede un rapido assorbimento e distribuzione nei tessuti corporei, con l'escrezione renale come principale via di eliminazione. Come per tutti gli antibiotici, si raccomanda di effettuare test di suscettibilità appropriati per garantire la sua efficacia contro patogeni specifici.

Formula: C₁₅H₁₇N₇O₅S₃

InChI: InChI=1/C15H17N7O5S3.Na/c1-21-14(18-19-20-21)30-6-8-5-29-13-15(27-2,17-9(23)7-28-4-3-16)12(26)22(13)10(8)11(24)25;/h13H,4-7H2,1-2H3,(H,17,23)(H,24,25);/q;+1/p-1/t13?,15-;/m0./s1

InChI key: InChIKey=QTNLVCQCRNPXAJ-PBCQUBLHSA-N

SMILES: N(C(CSCC#N)=O)[C@@]1(OC)[C@@]2(N(C1=O)C(C(O)=O)=C(CSC=3N(C)N=NN3)CS2)[H].[Na]

Sinonimi:

• 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-((((cyanomethyl)thio)acetyl)amino)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-, monosodium salt, (6R-cis)-
• 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-((((cyanomethyl)thio)acetyl)amino)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-, sodium salt, (6R-cis)-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[2-[(cyanomethyl)thio]acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, sodium salt (1:1), (6R,7S)-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[[(cyanomethyl)thio]acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, monosodium salt, (6R,7S)-
• CMZ sodium
• CS 1170 sodium
• CS-1170 sodium salt
• Cefmetazole sodium [USAN:JAN]
• Cefmetazole-Na
• Cefmetazon
• Cefmetazone
• Metafar
• Metazol
• SKF 83088 sodium
• Sodium (6R,7S)-7-(2-((cyanomethyl)thio)acetamido)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylate
• Sodium cefmetazole
• U 72791A
• Unii-37Y9Vr4W7A
• Zefazone
• Zefazone in plastic container
• sodium (6R,7S)-7-({[(cyanomethyl)sulfanyl]acetyl}amino)-7-methoxy-3-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
• sodium (7S)-7-({[(cyanomethyl)sulfanyl]acetyl}amino)-7-methoxy-3-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
• (6R)-7-[[[(Cyanomethyl)thio]acetyl]amino]-7β-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid sodium salt
• (6R,7S)-7-[[2-[(Cyanomethyl)thio]acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid Sodium Salt
• CEFMETAZOLE
• Cefmetazole sodium

Cefmetazole sodium, 921μg/mg

CAS: 56796-39-5

Cefmetazole is used to study the effect of expression, binding, and inhibition of penicillin-binding proteins (with the exception of PBP2) on bacterial cell wall mucopeptide synthesis. It is also used to study protein mediated antibiotic transport. This Thermo Scientific Chemicals brand product was

Formula: C₁₅H₁₆N₇O₅S₃Na

Peso molecolare: 493.52

Ref: 02-J66348

Cefmetazole (sodium)

CAS: 56796-39-5

Formula: C₁₅H₁₆N₇NaO₅S₃

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 493.5162

Ref: IN-DA00IA4D

Cefmetazole sodium

CAS: 56796-39-5

Cefmetazole sodium: semisynthetic cephamycin, broad-spectrum, effective against infections, no severe side effects.

Formula: C₁₅H₁₆N₇NaO₅S₃

Purezza: 92.05% - 99.87%

Colore e forma: White Solid

Peso molecolare: 493.52

Ref: TM-T1070

Cefmetazole Sodium

CAS: 56796-39-5

Cefmetazole Sodium

Purezza: 98%

Peso molecolare: 493.52g/mol

Ref: 54-OR1029116

Cefotetan Impurity 1 Sodium Salt (Cefmetazole Sodium Salt)

CAS: 56796-39-5

Formula: C₁₅H₁₆N₇O₅S₃·Na

Colore e forma: White To Off-White Solid

Peso molecolare: 470.53 22.99

Ref: 4Z-C-243005

Cefmetazole sodium

CAS: 56796-39-5

Cefmetazole sodium

Purezza: ≥90%

Peso molecolare: 493.52g/mol

Ref: 54-BUP16810

Cefmetazole sodium salt

CAS: 56796-39-5

Formula: C₁₅H₁₆N₇O₅S₃Na

Colore e forma: White to off-white or pale yellow powder

Peso molecolare: 493.52

Ref: 7W-GA4116

Cefmetazole Sodium Salt

CAS: 56796-20-4, 56796-39-5

Formula: C₁₅H₁₆N₇NaO₅S₃

Purezza: >92.0%(HPLC)

Colore e forma: White to Light yellow powder to crystal

Peso molecolare: 493.51

Ref: 3B-C3029

Cefmetazole sodium

CAS: 56796-39-5

Purezza: 98%

Peso molecolare: 493.510009765625

Ref: 10-F825606

Cefmetazole Sodium

Prodotto controllato

CAS: 56796-39-5

Applications Cefmetazole sodium is used clinically in combination with Tanreqing for the treatment of Pulmonary infections like Senile Emphysema and other acute bacterial infections.
References Zhou, G., et al.: Zhonghua Zhongyiyao Xuekan, 32, 622 (2014); Luo, Y., et al.: Zhongguo Yiyuan Yaoxue Zazhi, 34, 1851 (2014); Fan, M., et al.: Shiyong Yaowu Yu Linchuang, 15, 10 (2012)

Formula: C₁₅H₁₆N₇O₅S₃·Na

Colore e forma: Neat

Peso molecolare: 493.52

Ref: TR-C242910

Cefmetazole sodium

CAS: 56796-39-5

Cefmetazole sodium is a penicillin-type antibiotic that inhibits the synthesis of bacterial cell walls. It binds to the penicillin-binding proteins in the bacterial cell wall by competitive inhibition, preventing the formation of an antibiotic-inhibitor complex with the enzyme cell wall synthesis that is required for cell wall biosynthesis, inhibiting protein synthesis and cell division. Cefmetazole sodium has been shown to be active against a wide variety of bacteria, including gram-positive and gram-negative bacteria. The drug's activity against most strains of methicillin-resistant Staphylococcus aureus (MRSA) has been confirmed. Cefmetazole sodium is used to treat infectious diseases such as pneumonia and urinary tract infections. Drug interactions are possible, but not well understood at this time.

Formula: C₁₅H₁₇N₇O₅S₃•Na

Purezza: Min. 93 Area-%

Colore e forma: Powder

Peso molecolare: 494.53 g/mol

Ref: 3D-FC38036