CAS 57-63-6

Etinilestradiolo

Descrizione:

Etinilestradiolo è un estrogeno sintetico, utilizzato principalmente in contraccettivi ormonali e terapia ormonale sostitutiva. È caratterizzato dalla sua potente attività estrogenica, che è significativamente più forte di quella dell'estradiolo naturale. Etinilestradiolo è una polvere cristallina bianca o bianco sporco che è scarsamente solubile in acqua ma solubile in solventi organici come etanolo e acetone. La sua formula chimica è C20H24O2 e ha un peso molecolare di circa 296,4 g/mol. Il composto presenta un gruppo etinile nella posizione C17, che ne migliora la biodisponibilità orale e la stabilità metabolica rispetto agli estrogeni naturali. Etinilestradiolo agisce legandosi ai recettori degli estrogeni, influenzando vari processi fisiologici, inclusa la regolazione del ciclo mestruale e lo sviluppo delle caratteristiche sessuali secondarie. A causa dei suoi effetti estrogenici, può anche avere effetti collaterali, incluso un aumento del rischio di eventi tromboembolici. Essendo un agente farmaceutico ampiamente utilizzato, è essenziale considerare la sua farmacocinetica, le potenziali interazioni e le controindicazioni nelle applicazioni cliniche.

Formula: C₂₀H₂₄O₂

InChI: InChI=1S/C20H24O2/c1-3-20(22)11-9-18-17-6-4-13-12-14(21)5-7-15(13)16(17)8-10-19(18,20)2/h1,5,7,12,16-18,21-22H,4,6,8-11H2,2H3/t16-,17-,18+,19+,20+/m1/s1

InChI key: InChIKey=BFPYWIDHMRZLRN-SLHNCBLASA-N

SMILES: C[C@@]12[C@]([C@]3([C@](CC1)(C=4C(CC3)=CC(O)=CC4)[H])[H])(CC[C@]2(C#C)O)[H]

Sinonimi:

• (17Alpha)-17-Ethynylestra-1,3,5(10)-Triene-3,17-Diol
• (17Beta)-17-Ethynylestra-1,3,5(10)-Triene-3,17-Diol
• (17α)-19-Norpregna-1,3,5(10)-trien-20-yne-3,17-diol
• (8Alpha,13Alpha,17Beta)-17-Ethynylestra-1,3,5(10)-Triene-3,17-Diol
• (8Xi,9Xi,14Xi,17Beta)-17-Ethynylestra-1,3,5(10)-Triene-3,17-Diol
• 17-Ethinyl-3,17-estradiol
• 17-Ethinylestradiol
• 17-Ethynyl Estradiol
• 17-Ethynyl-3,17-dihydroxy-1,3,5-oestratriene
• 17-Ethynylestra-1,3,5(10)-Triene-3,17-Diol
• 17-Ethynylestra-1,3,5(10)-triene-3,17β-diol
• 17-Ethynylestradiol
• 17-Nor-17α-pregna-1,3,5-(10)-trien-20-yne-3,17-diol
• 17A-Ethynyl-1,3,5(10)-Estratriene-3,17B-Diol
• 17Alpha-Ethynyl-3,17-Dihydroxy-Delta-(Sup1,3,5)-Estratriene
• 17alpha-Ethynyl-3-hydroxy-1,3,5(10)-estratrien-17beta-ol
• 17α-Ethinyl estradiol (EE2)
• 17α-Ethinyl-1,3,5(10)-estratriene-3,17-diol
• 17α-Ethinyl-17β-estradiol
• 17α-Ethinyl-3,17-dihydroxy-Δ1,3,5-estratriene
• 17α-Ethinyl-3,17-dihydroxy-Δ^1,3,5-estratriene
• 17α-Ethinylestra-1,3,5(10)-triene-3,17β-diol
• 17α-Ethinylestradiol
• 17α-Ethynylestra-1,3,5(10)-triene-3,17β-diol
• 17α-Ethynylestra-3,17β-diol
• 17α-Ethynylestradiol
• 19-Nor-17Alpha-Pregna-1,3,5(10)-Trien-20-Yne-3,17,Diol
• 19-Nor-17α-pregna-1,3,5(10)-trien-20-yne-3,17-diol
• 19-Nor-17α-pregna-1,3,5(10)-trien-20-yne-3,17β-diol
• 19-Norpregna-1,3,5(10)-trien-20-yne-3,17-diol, (17alpha)-
• 19-Norpregna-1,3,5(10)-trien-20-yne-3,17-diol, (17α)-
• 3,17Beta-Dihydroxy-17Alpha-Ethynyl-1,3,5(10)-Estratriene
• Acetylene estradiol
• Amenoron
• Anovlar
• Chee-O-Gen
• Chee-O-Genf
• Diognat-E
• Diogyn-E
• Dyloform
• EE
• Esteed
• Estigyn
• Estinyl
• Eston-E
• Estone
• Estoral
• Estoral (Orion)
• Estorals
• Estra-1,3,5(10)-Triene-3,17Beta-Diol, 17Alpha-Ethynyl-
• Estradiol, 17-ethynyl-
• Estroals
• Ethidol
• Ethinoral
• Ethinyl estradiol
• Ethinyloestradiol
• Ethynyl estradiol
• Ethynylestradiol
• Ethynyloestradiol
• Eticyclin
• Eticyclol
• Etinestrol
• Etinestryl
• Etinilestradiol
• Etinoestryl
• Etistradiol
• Feminone
• Follicoral
• Ginestrene
• Gynofen
• Inestra
• Linoral
• Lynoral
• Menolyn
• Microfollin
• Neo-Estrone
• Novestrol
• Novinet
• Nsc 10973
• Oradiol
• Orestralyn
• Palonyl
• Perovex
• Primogyn
• Primogyn C
• Primogyn C(Or M)
• Primogyn M
• Progynon C
• Prosexol
• Roldiol
• Spanestrin

Ethynylestradiol

CAS: 57-63-6

Formula: C₂₀H₂₄O₂

Purezza: >98.0%(T)(HPLC)

Colore e forma: White to Light yellow to Light orange powder to crystal

Peso molecolare: 296.41

Ref: 3B-E0037

Ethinylestradiol

CAS: 57-63-6

Colore e forma: Neat

Ref: 61-FOR0123.00

Ethinylestradiol

CAS: 57-63-6

Ethinylestradiol

Formula: C₂₀H₂₄O₂

Purezza: 97.0%

Colore e forma: Off-White

Peso molecolare: 296.17763

Ref: 47-421

ETHINYLESTRADIOL FOR SYSTEM SUITABILITY CRS

CAS: 57-63-6

ETHINYLESTRADIOL FOR SYSTEM SUITABILITY CRS

Ref: 41-Y0001124

ETHINYLESTRADIOL CRS

CAS: 57-63-6

ETHINYLESTRADIOL CRS

Colore e forma: Added Modified

Ref: 41-E1900000

ETHINYLESTRADIOL RS

CAS: 57-63-6

ETHINYLESTRADIOL RS

Ref: 41-ICRS0305

Ethinyl Estradiol

CAS: 57-63-6

Estrogens and progestins

Formula: C₂₀H₂₄O₂

Colore e forma: White Light Yellow Crystalline Powder

Peso molecolare: 296.17763

Ref: 45-1260001

Ethynyl estradiol

CAS: 57-63-6

Ethynyl estradiol is a semisynthetic alkylated ESTRADIOL with a 17-alpha-ethinyl substitution,which has high estrogenic potency when administered orally.

Formula: C₂₀H₂₄O₂

Purezza: 99.06% - 99.75%

Colore e forma: Fine White To Creamy White Crystalline Powder

Peso molecolare: 296.40

Ref: TM-T1424

Ethinyl Estradiol

CAS: 57-63-6

Formula: C₂₀H₂₄O₂

Colore e forma: White To Off-White Solid

Peso molecolare: 296.41

Ref: 4Z-E-099

Ethynyl estradiol

CAS: 57-63-6

Ethynyl estradiol

Purezza: ≥98%

Peso molecolare: 296.4g/mol

Ref: 54-BUP16737

Ethynyl estradiol

CAS: 57-63-6

Ethynyl estradiol

Purezza: 98%

Peso molecolare: 296.4g/mol

Ref: 54-OR1030255

Ethinylestradiol

CAS: 57-63-6

Formula: C₂₀H₂₄O₂

Purezza: ≥ 98.0%

Colore e forma: White to off-white powder

Peso molecolare: 296.40

Ref: 7W-GP3324

Ethinylestradiol-d9

CAS: 57-63-6

Formula: C₂₀H₁₅D₉O₂

Peso molecolare: 305.46

Ref: 4Z-E-4611

17a-Ethinylestradiol

Prodotto controllato

CAS: 57-63-6

Formula: C₂₀H₂₄O₂

Colore e forma: Neat

Peso molecolare: 296.40

Ref: 04-C13245100

Ethinylestradiol

CAS: 57-63-6

Colore e forma: Neat

Ref: 86-MM0123.00

17a-Ethinylestradiol 100 µg/mL in Acetonitrile

Prodotto controllato

CAS: 57-63-6

Formula: C₂₀H₂₄O₂

Colore e forma: Single Solution

Peso molecolare: 296.40

Ref: 04-XA13245100AL

GB 31660.2-2019 Antibiotics Mixture 168 30-100 µg/mL in Methanol

Prodotto controllato

CAS: 140-66-9, 25154-52-3, 50-27-1, 50-28-2, 53-16-7, 56-53-1, 57-63-6, 80-05-7

Colore e forma: Mixture

Ref: 04-A50000168ME

Ethinylestradiol-13C2

CAS: 57-63-6

Formula: C₁₈₁₃C₂H₂₄O₂

Peso molecolare: 298.39

Ref: 4Z-E-4610

Ethinylestradiol RS

CAS: 57-63-6

Colore e forma: White To Pale Yellow

Ref: 2K-1023000021

Ethynyl Estradiol-2,4,9,6,6,16,16-d7 (Major)

Prodotto controllato

CAS: 57-63-6

Applications Isotope labelled Ethynyl Estradiol (E685100), an oral contraceptive (1), is a synthetic steroid with high oral estrogenic potency. Used in estrogen replacement therapy (2). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.
References 1. Koetsawang, S. et al.: Contraception. 1982 March:25(3) p231-2412. Cuttler, L. et al.: J. Endocrinol. Metab. 1985 Jun;60(6):1087-92.

Formula: C₂₀H₁₇D₇O₂

Colore e forma: White To Off-White

Peso molecolare: 303.45

Ref: TR-E685104

Ethynyl Estradiol

Prodotto controllato

CAS: 57-63-6

Applications Ethynyl Estradiol, an oral contraceptive (1), is a synthetic steroid with high oral estrogenic potency. Used in estrogen replacement therapy. (2)This compound is a contaminant of emerging concern (CECs). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References 1. Koetsawang, S. et al.: Contraception. 1982 March:25(3) p231-2412. Cuttler, L. et al.: J. Endocrinol. Metab. 1985 Jun;60(6):1087-92.

Formula: C₂₀H₂₄O₂

Colore e forma: Off-White

Peso molecolare: 296.40

Ref: TR-E685100

(1S,10R,11S,14R,15S)-14-ethynyl-15-methyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-2(7),3,5-triene-5,14-diol

CAS: 57-63-6

Formula: C₂₀H₂₄O₂

Purezza: 98%

Colore e forma: Liquid

Peso molecolare: 296.41

Ref: 10-F358085

Ethynyl Estradiol-d7

Prodotto controllato

CAS: 57-63-6

Formula: C₂₀D₇H₁₇O₂

Colore e forma: Neat

Peso molecolare: 303.447

Ref: TR-E685103

Ethynylestradiol

CAS: 57-63-6

Ethynylestradiol is a synthetic estrogen that is used in hormone replacement therapy. It belongs to the group of estrogens and has been shown to be a potent inhibitor of ovarian activity. Ethinyl estradiol is metabolized through catechol-O-methyltransferase (COMT) and sulfotransferases, which leads to an increased rate constant for its clearance from plasma. The drug also has interactions with other drugs, such as protease inhibitors, which may lead to disease activity or toxicity in the liver. Ethynylestradiol binds specifically to bcl-2 protein, which may be related to its anti-inflammatory properties.

Formula: C₂₀H₂₄O₂

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 296.4 g/mol

Ref: 3D-FE23175