CAS 571189-51-0

6-Acetil-8-ciclopentil-5-metil-2-[[5-(4-metilpiperazin-1-il)pyridin-2-il]amino]-8H-pirido[2,3-d]pirimidin-7-one

Descrizione:

6-Acetil-8-ciclopentil-5-metil-2-[[5-(4-metilpiperazin-1-il)pyridin-2-il]amino]-8H-pirido[2,3-d]pirimidin-7-one è un composto organico complesso caratterizzato dalla sua struttura multiciclica, che include un nucleo di pirido-pirimidina. Questo composto presenta vari gruppi funzionali, tra cui un gruppo acetile e una porzione di piperazina, che contribuiscono alla sua potenziale attività biologica. La presenza del gruppo ciclopentile aggiunge al suo carattere idrofobico, influenzando la sua solubilità e interazione con le membrane biologiche. È probabile che il composto mostri specifiche proprietà farmacologiche, rendendolo di interesse nella chimica medicinale, in particolare nello sviluppo di agenti terapeutici. La sua struttura molecolare suggerisce potenziali interazioni con bersagli biologici, coinvolgendo possibilmente l'inibizione di enzimi o la modulazione di recettori. Il numero CAS 571189-51-0 identifica univocamente questa sostanza nei database chimici, facilitando gli sforzi di ricerca e sviluppo. In generale, la struttura intricata del composto e i suoi gruppi funzionali lo posizionano come un candidato per ulteriori indagini nella scoperta e nello sviluppo di farmaci.

Formula: C₂₅H₃₁N₇O₂

InChI: InChI=1S/C25H31N7O2/c1-16-20-15-27-25(28-21-9-8-19(14-26-21)31-12-10-30(3)11-13-31)29-23(20)32(18-6-4-5-7-18)24(34)22(16)17(2)33/h8-9,14-15,18H,4-7,10-13H2,1-3H3,(H,26,27,28,29)

InChI key: InChIKey=PBSZUBKCQUPZFE-UHFFFAOYSA-N

SMILES: O=C1N(C=2C(C(C)=C1C(C)=O)=CN=C(NC3=CC=C(C=N3)N4CCN(C)CC4)N2)C5CCCC5

Sinonimi:

• 6-Acetyl-8-cyclopentyl-5-methyl-2-[[5-(4-methylpiperazin-1-yl)pyridin-2-yl]amino]-8H-pyrido[2,3-d]pyrimidin-7-one
• Pyrido[2,3-d]pyrimidin-7(8H)-one, 6-acetyl-8-cyclopentyl-5-methyl-2-[[5-(4-methyl-1-piperazinyl)-2-pyridinyl]amino]-
• 6-Acetyl-8-cyclopentyl-5-methyl-2-[[5-(4-methyl-1-piperazinyl)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidin-7(8H)-one

Pyrido[2,3-d]pyrimidin-7(8H)-one, 6-acetyl-8-cyclopentyl-5-methyl-2-[[5-(4-methyl-1-piperazinyl)-2-pyridinyl]amino]-

CAS: 571189-51-0

Formula: C₂₅H₃₁N₇O₂

Purezza: 99%

Colore e forma: Solid

Peso molecolare: 461.5593

Ref: IN-DA01SHRQ

6-Acetyl-8-cyclopentyl-5-methyl-2-((5-(4-methylpiperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one

CAS: 571189-51-0

6-Acetyl-8-cyclopentyl-5-methyl-2-((5-(4-methylpiperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one

Purezza: 99%

Peso molecolare: 461.57g/mol

Ref: 54-OR1065264

Palbociclib Impurity 31

CAS: 571189-51-0

Formula: C₂₅H₃₁N₇O₂

Colore e forma: Yellow Solid

Peso molecolare: 461.57

Ref: 4Z-P-196035

Pyrido[2,3-d]pyrimidin-7(8H)-one, 6-acetyl-8-cyclopentyl-5-methyl-2-[[5-(4-methyl-1-piperazinyl)-2-pyridinyl]amino]-

CAS: 571189-51-0

Purezza: 98%

Peso molecolare: 461.57000732421875

Ref: 10-F864462

N-Methyl Palbociclib

Prodotto controllato

CAS: 571189-51-0

Applications N-Methyl Palbociclib is an impurity of Palbociclib (P139900), a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6 which may be useful in the treatment of breast cancer.

Formula: C₂₅H₃₁N₇O₂

Colore e forma: Neat

Peso molecolare: 461.559

Ref: TR-M571180

N-Methyl palbociclib

CAS: 571189-51-0

N-Methyl palbociclib is a compound that exhibits hepatocyte growth factor (HGF) neutralizing activity. It acts by binding to HGF and preventing its interaction with its receptor, leading to the inhibition of HGF-induced signaling pathways. N-Methyl palbociclib has been shown to inhibit the proliferation of human hepatocytes in vitro and has potential applications in the field of Life Sciences. Additionally, it has cytotoxic effects on various cell types, including those expressing epidermal growth factor (EGF)-like and neurotrophic factors receptors. This compound also exhibits inhibitory effects on interleukin-6 (IL-6) signaling, which plays a crucial role in inflammation and immune responses. Overall, N-Methyl palbociclib shows promising potential as a therapeutic agent targeting multiple pathways involved in cell growth and signaling.

Formula: C₂₅H₃₁N₇O₂

Purezza: Min. 95%

Peso molecolare: 461.6 g/mol

Ref: 3D-WXA18951

N-Methyl Palbociclib

CAS: 571189-51-0

N-Methyl Palbociclib is an impurity of the orally active selective CDK4 and CDK6 inhibitor Palbociclib (PD 0332991).

Formula: C₂₅H₃₁N₇O₂

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 461.56

Ref: TM-T78130