CAS 58-55-9

Teofillina

Descrizione:

Teofillina è un composto di metilxantina che si trova naturalmente, principalmente nelle foglie di tè e nel cacao. È classificato come un broncodilatatore, il che significa che aiuta a rilassare e aprire le vie aeree nei polmoni, risultando utile nel trattamento di malattie respiratorie come l'asma e la broncopneumopatia cronica ostruttiva (BPCO). La formula chimica di Teofillina è C7H8N4O2, e ha un peso molecolare di circa 180,17 g/mol. Teofillina presenta una solubilità moderata in acqua ed è più solubile nei solventi organici. La sua struttura presenta un sistema ad anello simile alla purina, che contribuisce alla sua attività biologica. Teofillina agisce inibendo gli enzimi fosfodiesterasi, portando a livelli aumentati di AMP ciclico, che promuove il rilassamento della muscolatura liscia bronchiale. Inoltre, ha proprietà anti-infiammatorie e può migliorare la funzione muscolare respiratoria. Sebbene generalmente ben tollerato, Teofillina può avere effetti collaterali, in particolare a dosi più elevate, tra cui disturbi gastrointestinali, insonnia e aumento della frequenza cardiaca. Il suo uso terapeutico richiede un attento monitoraggio dei livelli ematici a causa del suo stretto indice terapeutico.

Formula: C₇H₈N₄O₂

InChI: InChI=1S/C7H8N4O2/c1-10-5-4(8-3-9-5)6(12)11(2)7(10)13/h3H,1-2H3,(H,8,9)

InChI key: InChIKey=ZFXYFBGIUFBOJW-UHFFFAOYSA-N

SMILES: O=C1C2=C(N(C)C(=O)N1C)N=CN2

Sinonimi:

• 1,3-Dimethyl-1H-purine-2,6(3H,7H)-dione
• 1,3-Dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione
• 1,3-Dimethyl-2,3,6,9-tetrahydro-1H-purine-2,6-dione
• 1,3-Dimethyl-3,7-dihydro-purine-2,6-dione
• 1,3-Dimethylxanthine
• 1,3-dimethyl-3,4,5,7-tetrahydro-1H-purine-2,6-dione
• 3,7-Dihydro-1,3-dimethyl-1H-purine-2,6-dione
• 3,9-Dihydro-1,3-dimethyl-1H-purine-2,6-dione
• Accurbron
• Aerobin
• Aerolate
• Afonilm
• Apnecut
• Armophylline
• Asmax
• Austyn
• Bilordyl
• Brochoretard
• Bronkodyl
• Cetraphylline
• Chronophyllin
• Diffumal
• Dimethylxanthine
• Duraphyl
• Duraphyllin
• Egifilin
• Elan
• Elixophyllin
• Elixophylline
• Etheophyl
• Euphylong
• Insanovin
• LaBID
• Lanophyllin
• Lasma
• Liquophylline
• Nuelin
• Optiphyllin
• Parkophyllin
• Phylobid
• Physpan
• Pro-Vent
• Pseudotheophylline
• PulmiDur
• Pulmo-Timelets
• Respbid
• Respicur
• Slo-Bid
• Slo-Phyllin
• Solosin
• Sustaire
• Talotren
• Telb-DS
• Telbans
• Teofilina
• Teonova
• Teotard
• Tesona
• Theo-DS
• Theo-Dur
• Theo-Nite
• Theo-Sav
• Theobid
• Theochron
• Theoclear
• Theodel
• Theodrip
• Theofol
• Theograd
• Theolair
• Theon
• Theopek
• Theophyl
• Theophyllin
• Theoplus
• Theostat
• Theotard
• Theovent
• Throphylline
• Unifyl
• Unilong
• Uniphyl
• Uniphyllin
• Xanthium
• 1H-Purine-2,6-dione, 3,7-dihydro-1,3-dimethyl-
• 1H-Purine-2,6-dione, 3,9-dihydro-1,3-dimethyl-

Theophylline

CAS: 58-55-9

1,3-Dimethyl-1H-purine-2,6(3H,9H)-dione

Formula: C₇H₈N₄O₂

Purezza: 97%

Peso molecolare: 180.16

Ref: IN-DG34182

Theophylline

CAS: 58-55-9

Formula: C₇H₈N₄O₂

Purezza: ≥ 99.0%

Colore e forma: White to off-white crystalline powder

Peso molecolare: 180.16

Ref: 7W-GP6302

Theophylline

CAS: 58-55-9

Theophylline

Formula: C₇H₈N₄O₂

Purezza: ≥ 98.0 % (HPLC)

Colore e forma: Powder

Peso molecolare: 180.17

Ref: 5G-82668

Caffeine EP Impurity A

CAS: 58-55-9

Formula: C₇H₈N₄O₂

Peso molecolare: 180.16

Ref: ST-EA-CP-C47001

Theophylline

CAS: 58-55-9

Formula: C₇H₈N₄O₂

Peso molecolare: 180.16

Ref: ST-EA-CP-T59000

Theophylline

Prodotto controllato

CAS: 58-55-9

Applications Xanthine derivative with diuretic, cardiac stimulant and smooth muscle relaxant activities; isomeric with theobromine. Small amounts occur in tea. Bronchodilator.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Cohen, J.L., et al.: Anal. Profiles Drug Subs., 4, 466 (1975); Svedmyr, K., et al.: Allergy, 37, 111 (1982);

Formula: C₇H₈N₄O₂

Colore e forma: Neat

Peso molecolare: 180.16

Ref: TR-T343850

Theophylline-[13C2,d6]

CAS: 58-55-9

Ref: BE-MCD-8150

Theophylline

CAS: 58-55-9

Ref: BE-促RMT17596

Theophylline in Methanol

CAS: 58-55-9

Methanol

Ref: BE-GBW(E)087088-100

Theophylline

CAS: 58-55-9

Formula: C₇H₈N₄O₂

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 180.167

Ref: 10-F095062

1,3-Dimethyl-2,6-dioxo-1,2,3,6-tetrahydropurine

Prodotto controllato

CAS: 58-55-9

1,3-Dimethyl-2,6-dioxo-1,2,3,6-tetrahydropurine (1,3DMP) is a drug that has been used experimentally as a congestive heart failure treatment. It is an analogue of theophylline and has been shown to have similar effects on the cardiovascular system. 1,3DMP can be metabolized by cytochrome P450 enzymes to form compounds that are active in the nucleus of cells and may affect gene expression. The drug has also been shown to have a protective effect on the bowel when administered with anhydrous sodium sulphate. 1,3DMP binds to DNA in the nucleus of cells and inhibits nuclear dna synthesis by competitive inhibition with the natural substrate S-adenosylmethionine. This binding prevents transcription of DNA into RNA and protein synthesis. 1,3DMP also binds to proteins in human serum and has pharmacological activities such as

Formula: C₇H₈N₄O₂

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 180.16 g/mol

Ref: 3D-FT28196

Theophylline Anhydrous pure, 99%

CAS: 58-55-9

Formula: C₇H₈N₄O₂

Purezza: min. 99%

Colore e forma: White to off -white to light yellow, Crystalline powder

Peso molecolare: 180.16

Ref: SR-56135