CAS 58288-50-9

Idrossocobalamina cloridrato

Descrizione:

Idrossocobalamina cloridrato è una forma di vitamina B12, specificamente un composto di cobalamina, caratterizzato dal suo colore rosso dovuto alla presenza di cobalto. È una vitamina solubile in acqua che svolge un ruolo cruciale in vari processi biologici, inclusa la sintesi del DNA, la formazione dei globuli rossi e la funzione neurologica. L'idrossocobalamina è spesso utilizzata in contesti clinici come trattamento per la carenza di vitamina B12 e come antidoto per il avvelenamento da cianuro grazie alla sua capacità di legarsi agli ioni di cianuro, formando un complesso non tossico. Il composto viene tipicamente somministrato per via intramuscolare o endovenosa, e la sua farmacocinetica prevede lo stoccaggio nel fegato, dove può essere rilasciato secondo necessità. Idrossocobalamina cloridrato è generalmente ben tollerato, con effetti collaterali rari, ma possono includere reazioni allergiche o reazioni nel sito di iniezione. La sua stabilità e efficacia lo rendono un agente terapeutico prezioso sia nella supplementazione nutrizionale che nella medicina d'emergenza.

Formula: C₆₂H₈₉CoN₁₃O₁₅P·xClH

InChI: InChI=1S/C62H90N13O14P.ClH.Co.H2O/c1-29-20-39-40(21-30(29)2)75(28-70-39)57-52(84)53(41(27-76)87-57)89-90(85,86)88-31(3)26-69-49(83)18-19-59(8)37(22-46(66)80)56-62(11)61(10,25-48(68)82)36(14-17-45(65)79)51(74-62)33(5)55-60(9,24-47(67)81)34(12-15-43(63)77)38(71-55)23-42-58(6,7)35(13-16-44(64)78)50(72-42)32(4)54(59)73-56;;;/h20-21,23,28,31,34-37,41,52-53,56-57,76,84H,12-19,22,24-27H2,1-11H3,(H15,63,64,65,66,67,68,69,71,72,73,74,77,78,79,80,81,82,83,85,86);1H;;1H2/q;;+3;/p-3

InChI key: InChIKey=KEHNCSYXYMMUCO-UHFFFAOYSA-K

SMILES: [OH-][Co+3]1234[N]=5C6(C)C7[N-]1C(C(C)(C7CC(N)=O)CCC(=O)NCC(C)OP(=O)([O-])OC8C(O)C(N9C=[N]2C=%10C9=CC(C)=C(C)C%10)OC8CO)=C(C)C%11=[N]3C(=CC%12=[N]4C(=C(C)C5C(CCC(N)=O)C6(CC(N)=O)C)C(CC(N)=O)(C)C%12CCC(N)=O)C(C)(C)C%11CCC(N)=O.Cl

Sinonimi:

• Cobinamide, Co-hydroxy-, f-(dihydrogen phosphate), inner salt, 3′-ester with (5,6-dimethyl-1-α-<span class="text-smallcaps">D</span>-ribofuranosyl-1H-benzimidazole-κN³), hydrochloride
• Cobinamide, Co-hydroxy-, f-(dihydrogen phosphate), inner salt, 3′-ester with (5,6-dimethyl-1-α-<span class="text-smallcaps">D</span>-ribofuranosyl-1H-benzimidazole-κN³), hydrochloride (1:?)
• Cobinamide, dihydroxide, dihydrogen phosphate (ester), mono(inner salt), 3′-ester with 5,6-dimethyl-1-α-<span class="text-smallcaps">D</span>-ribofuranosyl-1H-benzimidazole, hydrochloride
• Hydroxocobalamin Chloride
• Hydroxocobalamine Hydrochloride
• Vitamin B12A Hydrochloride
• hydroxocobalamin HCl
• hydroxy-[(1R,2R,3R,4Z,7S,9Z,12S,13S,14Z,17S,18S,19R)-2,13,18-tris(2-amino-2-oxo-ethyl)-7,12,17-tris(3-amino-3-oxo-propyl)-3-[3-[[(2R)-2-[[(2R,3S,4R,5S)-5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)tetrahydrofuran-3-yl]oxy-oxido-phosphoryl]oxypropyl]amino]-3-oxo-propyl]-3,5,8,8,13,15,18,19-octamethyl-2,7,12,17-tetrahydro-1H-corrin-21-yl]cobalt(1+) hydrochloride
• Hydroxocobalamin hydrochloride
• Cobinamide, Co-hydroxy-, f-(dihydrogen phosphate), inner salt, 3′-ester with (5,6-dimethyl-1-α-D-ribofuranosyl-1H-benzimidazole-κN3), hydrochloride
• Cobinamide, Co-hydroxy-, f-(dihydrogen phosphate), inner salt, 3′-ester with (5,6-dimethyl-1-α-D-ribofuranosyl-1H-benzimidazole-κN3), hydrochloride (1:?)

HYDROXOCOBALAMIN CRS

CAS: 58288-50-9

HYDROXOCOBALAMIN CRS

Ref: 41-H1428000

Cobinamide, Co-hydroxy-, f-(dihydrogen phosphate), inner salt, 3'-esterwith (5,6-dimethyl-1-a-D-ribofuranosyl-1H-benzimidazole-kN3),hydrochloride

CAS: 58288-50-9

Formula: C₆₂H₉₀ClCoN₁₃O₁₅P

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 1382.8161

Ref: IN-DA00E91P

Vitamin B12a hydrochloride

CAS: 58288-50-9

Vitamin B12a monohydrochloride (Hydroxocobalamin) is an essential water-soluble vitamin.a cyanide detoxifier and nutritional supplement, injection, inhalation.

Formula: C₆₂H₈₉CoN₁₃O₁₅P·xHCl

Colore e forma: Solid

Ref: TM-T204095

Hydroxocobalamin hydrochloride

CAS: 58288-50-9

Formula: C₆₂H₈₉CoN₁₃O₁₅P·HCl

Purezza: 96.0 - 102.0 %

Colore e forma: Off-white to dark red or brown crystalline powder

Peso molecolare: 1382.82

Ref: 7W-GE2054

Hydroxocobalamin Xhydrochloride

CAS: 58288-50-9

Hydroxocobalamin Xhydrochloride

Purezza: 98%

Peso molecolare: 1,382.82g/mol

Ref: 54-OR1013543

Vitamin B12a

CAS: 58288-50-9

Formula: C₆₂H₉₀ClCoN₁₃O₁₅P

Peso molecolare: 1382.82

Ref: 7W-GL8242

Hydroxocobalamin HCl

CAS: 58288-50-9

Hydroxocobalamin HCl is a vitamin that is required for the formation of coenzyme B12. It is used to treat megaloblastic anemia, pernicious anemia, and other conditions in which vitamin B12 is deficient. Hydroxocobalamin HCl also has been shown to have physiological effects, including the inhibition of enzyme activities such as nitrite reductase and sephadex g-100. This drug binds to a number of enzymes, including group P2 enzymes (e.g., nitrate reductase) and thermolytic enzymes (e.g., hydroxylases). Hydroxocobalamin HCl has a redox potential that allows it to act as a hydrogen donor in reactions with electron acceptors such as nitrite ion or oxygen. The mechanism of action of hydroxocobalamin includes its ability to reduce intramolecular hydrogen molecules, which can be transferred to other molecules in the reaction system such as

Formula: C₆₂H₈₉CoN₁₃O₁₅P•(HCl)x

Purezza: Min. 90 Area-%

Colore e forma: Powder

Peso molecolare: 1,346.35 g/mol

Ref: 3D-FH45888

Hydroxocobalamin Hydrochloride (>85%)

CAS: 58288-50-9

Applications Hydroxocobalamin Hydrochloride acts as a spin trap for radical polymerization in water when reduced with ascorbic acid.
References Ng, Y., et al.: Macromol. Res., 20, 473-476 (2012)

Formula: C₆₂H₈₉CoN₁₃O₁₅P·ClH

Colore e forma: Neat

Peso molecolare: 1382.82

Ref: TR-H862823

Cyanocobalamin EP Impurity H Chloride (Hydroxocobalamin Chloride)

CAS: 58288-50-9

Formula: C₆₂H₈₉CoN₁₃O₁₅P·HCl

Peso molecolare: 1382.82 36.46

Ref: 4Z-C-165020