CAS 58546-56-8

Schisantherin A

Descrizione:

Schisantherin A è un composto naturale classificato come lignano, derivato principalmente dalla specie vegetale Schisandra chinensis, nota per le sue proprietà medicinali. Questo composto presenta una struttura molecolare complessa caratterizzata da più anelli aromatici e gruppi idrossilici, contribuendo alla sua attività biologica. Schisantherin A è riconosciuto per le sue proprietà antiossidanti, che aiutano a neutralizzare i radicali liberi e a ridurre lo stress ossidativo. Inoltre, è stato studiato per i suoi potenziali effetti neuroprotettivi, attività anti-infiammatorie e capacità di modulare varie vie di segnalazione nelle cellule. Il profilo farmacologico del composto suggerisce potenziali applicazioni nella medicina tradizionale, in particolare nel miglioramento della funzione epatica e nella promozione della salute generale. La sua solubilità e stabilità in vari solventi lo rendono adatto per ulteriori ricerche e sviluppi nei campi della farmacologia e della chimica dei prodotti naturali. Come per molti composti naturali, studi in corso sono essenziali per chiarire completamente i suoi meccanismi d'azione e il potenziale terapeutico.

Formula: C₃₀H₃₂O₉

InChI: InChI=1S/C30H32O9/c1-16-12-18-13-21-25(38-15-37-21)26(35-5)22(18)23-19(14-20(33-3)24(34-4)27(23)36-6)28(30(16,2)32)39-29(31)17-10-8-7-9-11-17/h7-11,13-14,16,28,32H,12,15H2,1-6H3

InChI key: InChIKey=UFCGDBKFOKKVAC-UHFFFAOYSA-N

SMILES: O(C)C1=C2C=3C(=CC4=C(C3OC)OCO4)CC(C)C(C)(O)C(OC(=O)C5=CC=CC=C5)C2=CC(OC)=C1OC

Sinonimi:

• (5R,6S,7S)-6-hydroxy-1,2,3,13-tetramethoxy-6,7-dimethyl-5,6,7,8-tetrahydrobenzo[3',4']cycloocta[1',2':4,5]benzo[1,2-d][1,3]dioxol-5-yl benzoate
• (5S,6S,7S)-6-hydroxy-1,2,3,13-tetramethoxy-6,7-dimethyl-5,6,7,8-tetrahydrobenzo[3',4']cycloocta[1',2':4,5]benzo[1,2-d][1,3]dioxol-5-yl benzoate
• (5S-(5alpha,6beta,7beta))-5,6,7,8-Tetrahydro-1,2,3,13-tetramethoxy-6,7-dimethylbenzo(3,4)cycloocta(1,2-f)(1,3)benzodioxole-5,6-diol 5-benzoate
• 6-Hydroxy-1,2,3,13-Tetramethoxy-6,7-Dimethyl-5,6,7,8-Tetrahydrobenzo[3',4']Cycloocta[1',2':4,5]Benzo[1,2-D][1,3]Dioxol-5-Yl Benzoate
• Benzo(3,4)cycloocta(1,2-f)(1,3)benzodioxole-5,6-diol, 5,6,7,8-tetrahydro-1,2,3,13-tetramethoxy-6,7-dimethyl-, 5-benzoate, (5S-(5alpha,6beta,7beta))-
• Benzo[3,4]cycloocta[1,2-f][1,3]benzodioxole-5,6-diol, 5,6,7,8-tetrahydro-1,2,3,13-tetramethoxy-6,7-dimethyl-, 5-benzoate, (5S,6S,7S,13aS)-
• Benzo[3,4]cycloocta[1,2-f][1,3]benzodioxole-5,6-diol, 5,6,7,8-tetrahydro-1,2,3,13-tetramethoxy-6,7-dimethyl-, 5-benzoate, stereoisomer
• Gomisin C
• Schizantherin A
• Wuweizi ester A
• Schisantherin A

Schisantherin A

CAS: 58546-56-8

Formula: C₃₀H₃₂O₉

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 536.5697

Ref: IN-DA00E96C

Schizantherin A

CAS: 58546-56-8

Formula: C₃₀H₃₂O₉

Peso molecolare: 536.58

Ref: 7W-GY0185

Schisantherin A

CAS: 58546-56-8

Schisantherin A

Purezza: ≥98%

Peso molecolare: 536.57g/mol

Ref: 54-BUP00173

Schisantherin A

CAS: 58546-56-8

Schisantherin A

Purezza: 98%

Peso molecolare: 536.57g/mol

Ref: 54-OR1025610

Gomisin C

CAS: 58546-56-8

Formula: C₃₀H₃₂O₉

Purezza: >98.0%(HPLC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 536.58

Ref: 3B-G0538

Schizantherin A

CAS: 58546-56-8

Schisantherin A exhibits anti-tussive, sedative, anti-inflammatory, antioxidant, anti-osteoporotic, neuroprotective, cognition enhancing, and cardioprotective activities. Schisantherin A can significantly attenuate Aβ1-42-induced learning and memory impairment and noticeably improve the histopathological changes in the hippocampus. Schisantherin A exhibits neuroprotection against 1-methyl-4-phenylpyridinium ion (MPP(+)) through the regulation of two distinct pathways including increasing CREB-mediated Bcl-2 expression and activating PI3K/Akt survival signaling.

Formula: C₃₀H₃₂O₉

Purezza: 95%~99%

Peso molecolare: 536.577

Ref: BP-BP1267

Schisantherin A

CAS: 58546-56-8

Schisantherin A, a lignan from Schisandra fruit, is used as an antitussive, tonic, and sedative.

Formula: C₃₀H₃₂O₉

Purezza: 98% - 99.989

Colore e forma: Solid

Peso molecolare: 536.57

Ref: TM-T2913

Schisantherin a

CAS: 58546-56-8

Carboxylic acid with additional oxygen functions

Formula: C₃₀H₃₂O₉

Purezza: ≥ 95.0 % (HPLC)

Colore e forma: Powder

Peso molecolare: 536.58

Ref: 5G-89316

Gomisin C

Prodotto controllato

CAS: 58546-56-8

Gomisin C is a natural compound that has been shown to have antioxidant and anti-inflammatory effects. It has been shown to inhibit the mitochondrial membrane potential, which leads to cytosolic Ca2+ accumulation. Gomisin C also inhibits 3T3-L1 preadipocyte differentiation. This compound also inhibits the polymerase chain reaction of DNA in cells, as well as the formation of crystalline cellulose and fructus. Gomisin C has been shown to be effective against neuronal death induced by ischemia–reperfusion injury and skin tumor formation induced by chemical carcinogens. It also inhibits drug transporter activity, voltage-dependent calcium channels, and enzyme activities.

Formula: C₃₀H₃₂O₉

Purezza: 80%

Colore e forma: White Powder

Peso molecolare: 536.57 g/mol

Ref: 3D-FG09971

Schisantherin A

Prodotto controllato

CAS: 58546-56-8

Applications Schisantherin A is a ligand from Schisandra chinensis. It is capable of suppressing interleukin-1β-induced inflammation in human chondrocytes by inhibiting NF-κB and MAPKs activation.
References ?Liao, S. et al.: Eur. J. Pharmacol 780, 65 (2016); Liu, H., et al.: J Funct Foods 19, 296 (2015)

Formula: C₃₀H₃₂O₉

Colore e forma: Neat

Peso molecolare: 536.57

Ref: TR-S199100