CAS 58694-52-3

Tertiapin

CAS: 58694-52-3

Tertiapin (TPN), a potent inhibitor of the inward-rectifier K⁺ channels, blocked a G-protein-gated channel (GIRK1/4) and the ROMK1 channel with nanomolar affinities, however a closely related channel, IRK1, was insensitive to tertiapin. Thus, tertiapin will be a powerful ligand for purifying functional channels as well as for screening pharmaceutical agents against these channels.

Formula: C₁₀₆H₁₇₆N₃₄O₂₃S₅

Purezza: 96.5%

Colore e forma: White Powder

Peso molecolare: 2455.11

Ref: 01-4031297

Tertiapin

CAS: 58694-52-3

Tertiapin (reduced) is a synthetic bee venom peptide characterized by disulfide bonds between Cys3-Cys14 and Cys5-Cys18. It acts as an inhibitor of inward-rectifying potassium channels (potassium Channel) and can also block the activity of calcium-activated large conductance potassium channels. Tertiapin (reduced) is utilized in research related to diseases such as rheumatoid arthritis and multiple sclerosis.

Formula: C₁₀₆H₁₈₀N₃₄O₂₃S₅

Colore e forma: Solid

Peso molecolare: 2459.1

Ref: TM-TP2716

Tertiapin

CAS: 58694-52-3

Tertiapin is a synthetic bee venom peptide (Honey Bee, Apis mellifera) containing disulfide bonds between Cys3-Cys14 and Cys5-Cys18. It is an inward rectifier K+ channel blocker and also blocks the activity of calcium activated large conductance potassium channels. The pain and inflammation symptoms experienced after a bee sting is caused by this peptide even though bee venom also has the potential to treat pain and inflammation in conditions such as rheumatoid arthritis and multiple sclerosis.

Formula: C₁₀₆H₁₈₀N₃₄O₂₃S₅

Purezza: Min. 95%

Peso molecolare: 2,459.11 g/mol

Ref: 3D-FT111087

Tertiapin

CAS: 58694-52-3

Tertiapin is a synthetic bee venom peptide (Honey Bee, Apis mellifera) containing disulfide bonds between Cys3-Cys14 and Cys5-Cys18. It is an inward rectifier K+ channel blocker and also blocks the activity of calcium activated large conductance potassium channels. The pain and inflammation symptoms experienced after a bee sting is caused by this peptide eventhough bee venom also has the potential to treat pain and inflammation in conditions such as rheumatoid arthritis and multiple sclerosis. This product is available as a 0.1mg vial.

Formula: C₁₀₆H₁₇₆N₃₄O₂₃S₅

Purezza: Min. 95%

Peso molecolare: 2,455.1 g/mol

Ref: 3D-PTK-4364-S