CAS 59-26-7

Tocainide

Descrizione:

Tocainide è un composto farmaceutico utilizzato principalmente come agente antiaritmico, in particolare nel trattamento delle aritmie ventricolari. Appartiene alla classe di farmaci noti come bloccanti dei canali sodici, che agiscono inibendo l'ingresso di ioni sodio durante la fase di depolarizzazione del potenziale d'azione cardiaco, stabilizzando così la membrana cardiaca e riducendo l'attività elettrica anomala. Tocainide è caratterizzato dalla sua formula chimica, che include un anello di piperidina, ed è tipicamente somministrato per via orale. La sostanza ha una solubilità moderata in acqua ed è nota per la sua tossicità relativamente bassa rispetto ad altri agenti antiaritmici. La farmacocinetica di Tocainide implica metabolismo epatico, ed è escreto principalmente attraverso i reni. Sebbene sia efficace, il suo uso può essere limitato da effetti collaterali come disturbi gastrointestinali e potenziali discrasie ematiche. A causa di questi fattori, il monitoraggio è essenziale durante il trattamento. In generale, Tocainide rappresenta un'opzione importante nella gestione di alcune aritmie cardiache, sebbene il suo uso clinico sia diminuito con l'avvento di nuovi agenti.

Formula: C₁₀H₁₄N₂O

InChI: InChI=1/C10H14N2O/c1-3-12(4-2)10(13)9-6-5-7-11-8-9/h5-8H,3-4H2,1-2H3

InChI key: InChIKey=NCYVXEGFNDZQCU-UHFFFAOYSA-N

SMILES: C(N(CC)CC)(=O)C=1C=CC=NC1

Sinonimi:

• Anacardone
• Astrocar
• Inicardio
• Kardiamid
• Leptamin
• Mediamid
• Niamine
• Nicamide
• Nicetamide
• Nicethamid
• Nicor
• Nicotinic Acid Diethyl Amide
• Nikethamide
• Nikotin
• N,N-diethyl-3-pyridinecarboxamide
• N,N-Diethylnicotinamide
• Percoral
• Procardine
• Pyridine-3-Carboxyldiethylamide
• Pyridine-3-Carboxylic Acid Diethylamide
• Reformin
• Salvacord
• Stellamine
• Stimulin
• Vasozol
• Diethyl-Nicotamide
• Dietilamide-Carbopiridina
• Dinacoryl
• Betapyrimidum
• Camphozone
• Cardiamid
• Cardiamine
• Cardamine
• Citocor
• Coracon
• Coraethamidum
• Coramine
• Corazone
• Cordiamin
• Cordynil
• Corediol
• Coretone
• Cormid
• Cornotone
• Corvitan
• Corvotone
• Danamine
• Elitone
• Hansacor
• N,N-diethylpyridine-3-carboxamide
• 3-(N,N-Diethylcarbamoyl)pyridine
• 3-Pyridinecarboxamide, N,N-diethyl-
• Anacordone
• Canfodiamina
• Carbamidal
• Cardiamide
• Cardimon
• Coractiv N
• Coramine (pharmaceutical)
• Cordiamine
• Cormed
• Cormotyl
• Corvin
• Corvitol
• Diethylnicotinamide
• Dynacoryl
• Ecoran
• Eucoran
• Kordiamin
• Nicetamida
• Nicethamide
• Ni-Cor
• Nicorine
• Nicotinamide, N,N-diethyl-
• Nicotinic acid diethylamide
• Nikardin
• Niketamide
• Niketamine
• Nikethamid
• Niketharol
• Nikethyl
• Nikorin
• Niquetamide
• Nsc 130820
• Nsc 169863
• Nsc 62103
• Pyricardyl
• Pyridine-3-carboxydiethylamide
• Rehormin
• Salvacard
• Sancora
• Solyacord
• Ventramine
• Nickethamide
• NIKETHAMIDUM
• LABOTEST-BB LT00134638

N,N-Diethylnicotinamide

CAS: 59-26-7

Formula: C₁₀H₁₄N₂O

Purezza: >98.0%(GC)(T)

Colore e forma: White or Colorless to Light orange to Yellow powder to lump to clear liquid

Peso molecolare: 178.24

Ref: 3B-D0514

NIKETHAMIDE CRS

CAS: 59-26-7

NIKETHAMIDE CRS

Formula: C₁₀H₁₄N₂O

Colore e forma: May Be Present In Various Forms. Oily Liquid. Crystalline Mass. Yellow. Transparent.

Peso molecolare: 178.231

Ref: 41-N0800000

Nikethamide

CAS: 59-26-7

Nikethamide is a stimulant which mainly influences the respiratory cycle. Widely known by its former sales name of Coramine, it was used in the mid-twentieth century as a medical countermeasure against tranquilizer overtreatments, before the advent of end

Formula: C₁₀H₁₄N₂O

Purezza: 99.42%

Colore e forma: Followed By A Faint Sensation Of The Warmth (Ntp 1992)

Peso molecolare: 178.23

Ref: TM-T0048

Nikethamide

CAS: 59-26-7

Formula: C₁₀H₁₄N₂O

Purezza: ≥ 98.0%

Colore e forma: Colourless or pale yellow oily liquid, or crystalline mass

Peso molecolare: 178.23

Ref: 7W-GP1304

Nikethamide, EP grade

CAS: 59-26-7

Formula: C₁₀H₁₄N₂O

Purezza: 99.0 - 101.0 % (anhydrous substance)

Colore e forma: An oily liquid or a crystalline mass, colourless or pale yellow

Peso molecolare: 178.23

Ref: 7W-GP1011

Nikethamide

CAS: 59-26-7

Colore e forma: Neat

Ref: 04-C15525900

Nikethamide

CAS: 59-26-7

Colore e forma: Neat

Ref: 61-FOR0627.00

Nikethamide

Prodotto controllato

CAS: 59-26-7

Formula: C₁₀H₁₄N₂O

Colore e forma: Neat

Peso molecolare: 178.23

Ref: 86-MM0627.00

N,N-Diethylnicotinamide

CAS: 59-26-7

N,N-Diethylnicotinamide

Purezza: 97%

Peso molecolare: 178.23g/mol

Ref: 54-OR926552

N,N-Diethylnicotinamide (Nikethamide)

CAS: 59-26-7

Formula: C₁₀H₁₄N₂O

Peso molecolare: 178.24

Ref: 4Z-N-133029

N,N-Diethylnicotinamide (Nikethamide)

CAS: 59-26-7

Applications Nikethamide is an analeptic agent. It was used in the mid-twentieth century as a medical countermeasure against tranquilizer overdoses, before the advent of endotracheal intubation and positive-pressure lung expansion. It is now considered to be of no value for such purposes, and may in fact be dangerous.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Bean, J., et al.: Biochem. Pharm., 35, 1011 (1986); Chakaravarti, M.: J. Pharmacol., 67, 153 (1939); Naik, S., et al.: Biochem. Pharm., 18, 2038 (1969); Martindale, The Extra Pharmacopoeia, 30th ed,, 1229

Formula: C₁₀H₁₄N₂O

Colore e forma: Off-White

Peso molecolare: 178.23

Ref: TR-N460000

N,N-Diethylnicotinamide

Prodotto controllato

CAS: 59-26-7

N,N-Diethylnicotinamide is a nicotinamide derivative that is used as an anti-inflammatory agent. It has been shown to inhibit the activity of enzymes such as acetylcholinesterase, phospholipase A2, and cyclooxygenase. N,N-Diethylnicotinamide has a synergistic effect with pentobarbital sodium in inducing chronic pulmonary inflammation in rats. This drug also has an acid complexing effect on fatty acids and nitrogen atoms. The coordination geometry of this drug is octahedral with two nitrogen atoms coordinated to one metal ion. N,N-Diethylnicotinamide can be synthesized by reacting nicotinic acid with diethylamine in the presence of 1 equivalent of hydrogen gas.

Formula: C₁₀H₁₄N₂O

Purezza: Min. 95%

Colore e forma: Colorless Clear Liquid

Peso molecolare: 178.23 g/mol

Ref: 3D-FD31942

N,N-Diethylnicotinamide

CAS: 59-26-7

Formula: C₁₀H₁₄N₂O

Peso molecolare: 178.24

Ref: ST-EA-CP-N35013