CAS 59-48-3

Ossindolo

Descrizione:

Ossindolo è un composto organico caratterizzato dalla sua struttura biciclica, che consiste in un anello di indolo fuso a un gruppo carbonilico. È un solido cristallino bianco a bianco sporco che è solubile in solventi organici come etanolo e cloroformio, ma ha una solubilità limitata in acqua. La formula molecolare di Ossindolo è C8H7NO e presenta un atomo di azoto all'interno della struttura dell'indolo, contribuendo alle sue proprietà basiche. Ossindolo è noto per il suo ruolo in varie attività biologiche, comprese le potenziali applicazioni in farmacologia, dove funge da impalcatura per lo sviluppo di farmaci mirati a disturbi neurologici e altre condizioni. Inoltre, può partecipare a varie reazioni chimiche, come sostituzioni elettrofile e ciclizzazioni, rendendolo un intermedio prezioso nella sintesi organica. I suoi derivati sono stati studiati per le loro proprietà anti-infiammatorie, analgesiche e antitumorali, evidenziando l'importanza del composto nella chimica medicinale. In generale, Ossindolo è un composto versatile con importanti implicazioni sia nella ricerca che nell'industria.

Formula: C₈H₇NO

InChI: InChI=1S/C8H7NO/c10-8-5-6-3-1-2-4-7(6)9-8/h1-4H,5H2,(H,9,10)

InChI key: InChIKey=JYGFTBXVXVMTGB-UHFFFAOYSA-N

SMILES: O=C1CC=2C(N1)=CC=CC2

Sinonimi:

• 1,3-Dihydroindol-2-one
• 1,3-dihydro-2H-indol-2-one
• 2,3-Dihidroindol-2-Ona
• 2,3-Dihydro-1H-indol-2-one
• 2,3-Dihydroindol-2-One
• 2,3-Dihydroindol-2-on
• 2,3-Dihydroindole-2-One
• 2-Indolinone
• 2-Indolone
• 2-Oxindole
• 2-Oxo-2,3-dihydroindole
• 2-Oxoindole
• 2-Oxoindoline
• 2H-Indol-2-one, 1,3-dihydro-
• Indol-2(3H)-one
• Indolin-2-one
• Indoline-2-one
• Nsc 274863
• O-(Aminophenyl)Acetic acid Lactam
• Oxidinole (Indolin-2-One)
• Oxindol
• Timtec-Bb Sbb004215

Oxindole

CAS: 59-48-3

Formula: C₈H₇NO

Purezza: >98.0%(GC)

Colore e forma: White to Light yellow to Light orange powder to crystal

Peso molecolare: 133.15

Ref: 3B-O0272

Oxindole, 97+%

CAS: 59-48-3

Oxindole is considered as indole analogue, which shows pharmacological activity. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code

Formula: C₈H₇NO

Purezza: 97+%

Colore e forma: White to dark cream to cream to brown, Powder

Peso molecolare: 133.15

Ref: 02-A18764

1,3-Dihydro-2H-indol-2-one

CAS: 59-48-3

Colore e forma: Light Red

Ref: 61-FOR0006.02

Oxindole

CAS: 59-48-3

Lactams, nesoi

Formula: C₈H₇NO

Colore e forma: White Crystalline Powder

Peso molecolare: 133.05276

Ref: 45-1A09990

Indolin-2-One

CAS: 59-48-3

Formula: C₈H₇NO

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 133.1473

Ref: IN-DA003R0B

Oxindole

CAS: 59-48-3

Oxindole (Indolin-2-one) is an aromatic heterocyclic building block.

Formula: C₈H₇NO

Purezza: 97.42% - 99.65%

Colore e forma: Off-White Crystalline Powder

Peso molecolare: 133.15

Ref: TM-Fr16741

2-Oxindole

CAS: 59-48-3

2-Oxindole

Formula: C₈H₇NO

Purezza: 98%

Colore e forma: light orange powder

Peso molecolare: 133.15g/mol

Ref: 54-OR30278

Oxindole

CAS: 59-48-3

Oxindole

Purezza: ≥95%

Peso molecolare: 133.15g/mol

Ref: 54-BUP19393

Diclofenac EP Impurity E (Oxindole)

CAS: 59-48-3

Formula: C₈H₇NO

Colore e forma: Brown Solid

Peso molecolare: 133.15

Ref: 4Z-D-069

1,3-Dihydro-2H-indol-2-one

CAS: 59-48-3

Formula: C₈H₇NO

Colore e forma: Neat

Peso molecolare: 133.15

Ref: 86-MM0006.02

Oxindole

CAS: 59-48-3

Formula: C₈H₇NO

Purezza: (HPLC) ≥ 97.0%

Colore e forma: White to light yellow or light orange crystalline powder

Peso molecolare: 133.15

Ref: 7W-GK4423

Oxindole (2-Indolone)

Prodotto controllato

CAS: 59-48-3

Applications Indole analogue; shows pharmacological activity.
References Mohammadi, M., et al.: Science, 276, 955 (1997), Bramson, H., et al.: J. Med. Chem., 44, 4339 (2001), Lane, M., et al.: Cancer Res., 61, 6170 (2001), Yu, B., et al.: Biochem. Pharmacol., 64, 1091 (2002),

Formula: C₈H₇NO

Colore e forma: Light Red

Peso molecolare: 133.15

Ref: TR-I627300

Diclofenac EP Impurity E

CAS: 59-48-3

Formula: C₈H₇NO

Peso molecolare: 133.15

Ref: ST-EA-CP-D20005

2-Indolone

CAS: 59-48-3

2-Indolone is a synthetic compound that belongs to the class of heterocyclic compounds. It is a trifluoroacetic acid derivative that has been shown to have potent antitumor activity, and it also inhibits cell proliferation. 2-Indolone has been shown to be an effective treatment for inflammatory diseases such as rheumatoid arthritis and Crohn's disease. This compound has been shown to bind to response elements in the promoter region of genes in the basic fibroblast line, and this binding leads to increased expression of gene products involved in inflammation and tumor suppression. The reaction mechanism for 2-indolone involves a two-step process, with activation energies for both steps being high. The first step involves protonation of the C2 hydroxyl group by trifluoroacetic acid, which leads to its displacement by hydrogen from water molecule H2O. In the second step, the oxindole ring opens up, with displacement of

Formula: C₈H₇NO

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 133.15 g/mol

Ref: 3D-FI24580

1,3-Dihydro-2H-indol-2-one

CAS: 59-48-3

Formula: C₈H₇NO

Purezza: 97%

Colore e forma: Solid, Chunks or Crystalline Powder

Peso molecolare: 133.15

Ref: 10-F093498

Oxindole

CAS: 59-48-3

Oxindole (Indolin-2-one) is an aromatic heterocyclic building block. 2-indolinone derivatives have become lead compounds in the research of kinase inhibitors.Oxindole structure has been used in receptor tyrosine kinases (RTKs) inhibitors such as SU4984 and intedanib, the RTK family represents an important therapeutic target for anti-cancer drug development.

Formula: C₈H₇NO

Purezza: 99.34%

Colore e forma: Off-White Crystalline Powder

Peso molecolare: 133.15

Ref: TM-FR16741