CAS 5909-24-0

Etil 4-cloro-2-(metiltio)-5-pirimidinacarboxilato

Descrizione:

Etil 4-cloro-2-(metiltio)-5-pirimidinacarboxilato, con il numero CAS 5909-24-0, è un composto chimico che appartiene alla classe dei derivati della pirimidina. Presenta un anello di pirimidina sostituito con un gruppo cloro in posizione 4 e un gruppo metiltio in posizione 2, insieme a un gruppo funzionale di estere etilico nella posizione dell'acido carbossilico. Questo composto è tipicamente caratterizzato dalla sua solubilità moderata a bassa in acqua, risultando più solubile in solventi organici come etanolo e diclorometano. La sua struttura suggerisce una potenziale attività biologica, rendendolo di interesse nella ricerca farmaceutica. La presenza dei sostituenti cloro e metiltio può influenzare la sua reattività e interazione con obiettivi biologici. Etil 4-cloro-2-(metiltio)-5-pirimidinacarboxilato può essere sintetizzato attraverso varie reazioni organiche, e i suoi derivati potrebbero mostrare diverse proprietà farmacologiche, comprese attività antimicrobiche o anti-infiammatorie. La corretta manipolazione e conservazione sono essenziali a causa della sua natura chimica, e le schede di sicurezza devono essere consultate per linee guida specifiche sulla sicurezza.

Formula: C₈H₉ClN₂O₂S

InChI: InChI=1S/C8H9ClN2O2S/c1-3-13-7(12)5-4-10-8(14-2)11-6(5)9/h4H,3H2,1-2H3

InChI key: InChIKey=SNNHLSHDDGJVDM-UHFFFAOYSA-N

SMILES: C(OCC)(=O)C=1C(Cl)=NC(SC)=NC1

Sinonimi:

• 2-Methylthio-4-chloro-5-ethoxycarbonylpyrimidine
• 4-Chloro-2-(methylthio)-5-pyrimidinecarboxylic acid ethyl ester
• 4-Chloro-2-(methylthio)pyrimidin-5-carboxylic acid ethyl ester
• 4-Chloro-2-Methylthio-5-Pyrimidnecarboxylat
• 4-Chloro-2-methane-sulfanylpyrimidine-5-carboxylic Acid Ethyl Ester
• 4-Chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester
• 4-Chloro-2-methanethiopyrimidine-5-carboxylic acid ethyl ester
• 4-Chloro-2-methylsulfanyl-pyrimidine-5-carboxylic acid ethyl ester
• 4-Chloro-2-methylsulfanylpyrimidine-5-carboxylic acid ethyl ester
• 4-Chloro-2-methylthio-5-carbethoxypyrimidine
• 4-Chloro-5-Ethoxycarbonyl-2-Methylthiopyrimidine
• 4-Chloro-5-carbethoxy-2-methylthiopyrimidine
• 5-Pyrimidinecarboxylic acid, 4-chloro-2-(methylthio)-, ethyl ester
• Ethyl 4-Chloro-2-(Methylsulfanyl)Pyrimidine-5-Carboxylate
• Ethyl 4-Chloro2-methylthiopyrimidine-5-carboxylate
• Ethyl 4-chloro-2-(methylthio)pyrimidine-5-carboxylate
• Ethyl 4-chloro-2-methylsulfanyl-5-pyrimidinecarboxylate
• Ethyl 4-chloro-2-methylthio-5-pyrimidine carboxylate
• Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate
• NSC 123534

Ethyl 4-Chloro-2-(methylthio)pyrimidine-5-carboxylate

CAS: 5909-24-0

Formula: C₈H₉ClN₂O₂S

Purezza: >97.0%(GC)

Colore e forma: White to Orange to Green powder to crystal

Peso molecolare: 232.68

Ref: 3B-E0841

Ethyl 4-chloro-2-(methylthio)pyrimidine-5-carboxylate, 98%

CAS: 5909-24-0

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₈H₉ClN₂O₂S

Purezza: 98%

Colore e forma: White to cream, powder

Peso molecolare: 232.68

Ref: 02-B22429

Ethyl 4-chloro-2-(methylthio)pyrimidine-5-carboxylate

CAS: 5909-24-0

Formula: C₈H₉ClN₂O₂S

Purezza: 96%

Colore e forma: Solid

Peso molecolare: 232.6873

Ref: IN-DA00371D

Ethyl 4-chloro-2-(methylthio)pyrimidine-5-carboxylate

CAS: 5909-24-0

Ethyl 4-chloro-2-(methylthio)pyrimidine-5-carboxylate

Formula: C₈H₉ClN₂O₂S

Purezza: 98%

Colore e forma: colourless to faint yellow crystalline solid

Peso molecolare: 232.69g/mol

Ref: 54-OR6605

Avanafil Impurity 61

CAS: 5909-24-0

Formula: C₈H₉ClN₂O₂S

Peso molecolare: 232.68

Ref: 4Z-A-2967

Ethyl 4-chloro-2-methylthiopyrimidine-5-carboxylate

CAS: 5909-24-0

Formula: C₈H₉ClN₂O₂S

Purezza: 96%

Colore e forma: Solid

Peso molecolare: 232.68

Ref: 10-F005213

Ethyl 4-Chloro-2-methylthiopyrimidine-5-carboxylate

Prodotto controllato

CAS: 5909-24-0

Applications A pyrimidine derivative as inhibitor of Streptococcus faecium, Lactobacillus casei, and Pediococcus cerevisiae.
References Coats, E.A., et al.: Eur. J. Med. Chem., 14, 261 (1979),

Formula: C₈H₉ClN₂O₂S

Colore e forma: Neat

Peso molecolare: 232.69

Ref: TR-E902000

Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate

CAS: 5909-24-0

Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate is a potent inhibitor of tyrosine kinases. It has been shown to inhibit the growth of cancer cells in vitro and in vivo. This drug has also been shown to be effective against various types of human cancer cell lines, such as human leukemia cells and myeloma cells. Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate inhibits the production of proteins vital for cell division by binding to tyrosine kinase. This binding prevents the formation of an enzyme complex with other enzymes that are required for protein synthesis, thereby inhibiting protein synthesis and cell division. The compound has also been shown to be a highly selective inhibitor of amines, which may contribute to its pharmacological effects.

Formula: C₈H₉ClN₂O₂S

Purezza: Min. 95%

Peso molecolare: 232.69 g/mol

Ref: 3D-FE15899

Avanafil Impurity 61

CAS: 5909-24-0

Formula: C₈H₉ClN₂O₂S

Peso molecolare: 232.68

Ref: ST-EA-CP-A84036