CAS 59122-46-2
:Misoprostol
Descrizione:
Misoprostol è un analogo sintetico della prostaglandina E1, utilizzato principalmente in medicina per la sua capacità di indurre contrazioni uterine e proteggere la mucosa gastrica. È caratterizzato dalla sua forma di polvere cristallina bianca a bianco sporco, solubile in acqua e in solventi organici come l'etanolo. Misoprostol agisce legandosi ai recettori delle prostaglandine, portando a vari effetti fisiologici, inclusa la stimolazione delle contrazioni uterine, la maturazione cervicale e l'inibizione della secrezione di acido gastrico. Le sue applicazioni terapeutiche includono la prevenzione delle ulcere gastriche nei pazienti che assumono farmaci antinfiammatori non steroidei (FANS), così come il suo utilizzo in ostetricia e ginecologia per l'aborto medico e la gestione dell'aborto spontaneo. Il composto è tipicamente somministrato per via orale o vaginale, e la sua farmacocinetica prevede un rapido assorbimento e metabolismo, con una emivita relativamente breve. Il profilo di sicurezza di Misoprostol è generalmente favorevole, ma può causare effetti collaterali come disturbi gastrointestinali e iperstimolazione uterina, richiedendo un attento monitoraggio durante l'uso.
Formula:C22H38O5
InChI:InChI=1/C22H38O5/c1-4-5-14-22(2,26)15-10-12-18-17(19(23)16-20(18)24)11-8-6-7-9-13-21(25)27-3/h10,12,17-18,20,24,26H,4-9,11,13-16H2,1-3H3/b12-10+/t17-,18-,20-,22?/s2
InChI key:InChIKey=OJLOPKGSLYJEMD-YUQTXCCYNA-N
SMILES:C(=C/CC(CCCC)(C)O)\[C@@H]1[C@@H](CCCCCCC(OC)=O)C(=O)C[C@H]1O
Sinonimi:- (+-)-Methyl (1R,2R,3R)-3-hydroxy-2-((E)-(4RS)-4-hydroxy-4-methyl-1-octenyl)-5-oxocyclopentaneheptanoate
- (11a,13E)-(±)-11,16-Dihydroxy-16-methyl-9-oxoprost-13-en-1-oic Acid Methyl Ester
- (11alpha,13E)-(+)-11alpha,16-Dihydroxy-16-methyl-9-oxoprost-13E-en-1-oic acid methyl ester
- (±)-15-Deoxy-(16RS)-16-hydroxy-16-methyl-PGE1 Methyl Ester
- Cytotec
- Isprelor
- Misogon
- Misoprost
- Misoprostil
- Misotac
- Prost-13-en-1-oic acid, 11,16-dihydroxy-16-methyl-9-oxo-, methyl ester, (11α,13E)-
- Sc 29333
- methyl (11alpha,13E)-11-hydroxy-16,16-dimethyl-9-oxoprost-13-en-1-oate
- methyl (11alpha,13E,16S)-11,16-dihydroxy-16-methyl-9-oxoprost-13-en-1-oate
- Vedi altri sinonimi
Ordinare per
Purezza (%)
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100
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0
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50
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90
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95
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100
13 prodotti.
MISOPROSTOL FOR SYSTEM SUITABILITY CRS
CAS:MISOPROSTOL FOR SYSTEM SUITABILITY CRSFormula:C22H38O5Peso molecolare:382.5341Misoprostol
CAS:Prostaglandins, thromboxanes and leukotrienes, their derivatives and structural analoguesFormula:C22H38O5Colore e forma:Colorless Light Yellow Liquid ViscousPeso molecolare:382.27192Misoprostol
CAS:Misoprostol, a prostaglandin E1 derivative, has a strong inhibitory effect on gastric acid secretion, while having a contractile effect on pregnancy.Formula:C22H38O5Purezza:99.78%Colore e forma:Water-Soluble Viscous LiquidPeso molecolare:382.53Misoprostol (0.10% wt/v in METHYL ACETATE), min. 97%
CAS:Formula:C22H38O5Purezza:min. 97%Colore e forma:White to Yellowish Oil (SOLUTION IN 10% METHYL ACETATE)Peso molecolare:382.53Misoprostol (Mixture of Diastereomers)
CAS:Formula:C22H38O5Colore e forma:Pale Yellow OilPeso molecolare:382.54Misoprostol
CAS:Formula:C22H38O5Purezza:≥ 99.0%Colore e forma:Colourless to light yellow liquidPeso molecolare:382.53Misoprostol
CAS:Prodotto controllatoApplications Misoprostol is a cytoprotective prostaglandin PGE1 analogue.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Graham, Y., et al.: Lancet, 2, 1277 (1988); Graham, D.Y., et al.: Ann. Int. Med., 119, 257 (1993); Fletcher, H., et al.: Obstet. Gynecol., 83, 244 (1994);Formula:C22H38O5Colore e forma:Light Yellow ViscousPeso molecolare:382.53Misoprostol, 1% in cellulose
CAS:Prodotto controllatoFormula:C22H38O5Colore e forma:Single SolutionPeso molecolare:382.53Misoprostol - 1% in cellulose
CAS:Prodotto controllatoMisoprostol is a nonsteroidal anti-inflammatory drug that is used for the treatment of dysmenorrhea and chronic non-specific low back pain. Misoprostol is also used in nephrology dialysis to decrease blood pressure, heart rate, and fluid retention in patients with congestive heart failure. It has been shown that misoprostol can be used to prevent preterm labor in pregnant women with a statistically significant reduction in the risk of miscarriage, preterm birth, and neonatal death. It has been shown that misoprostol can be administered orally or vaginally for the prevention of preterm labor. The pharmacokinetic properties of misoprostol are dose-dependent; higher doses result in faster absorption. Clinical relevance is dependent on the concentration-time curve, which determines how quickly the drug reaches its peak concentration. The clinical relevance of misoprostol is determined by the dose group (low dose or high dose), as well as diastolicFormula:C22H38O5Purezza:Min. 95%Colore e forma:PowderPeso molecolare:382.53 g/molMisoprostol
CAS:Prodotto controllatoMisoprostol is a prostaglandin E1 analogue that is used for the prevention and treatment of peptic ulcers. It also has been shown to reduce the risk of gastric cancer in the general population, although this effect may be limited to patients with a history of nonsteroidal anti-inflammatory drug use. Misoprostol has been found to be more effective in women who have already given birth than in those who have not, with a statistically significant reduction in the incidence of pregnancy during long-term use. Misoprostol is metabolized by cytochrome P450 enzymes and excreted primarily through the kidneys. The drug's pharmacokinetic properties are dependent on diastolic blood pressure, body mass index, and levels of blood sampling. Intrauterine placement can also increase its efficacy as it bypasses first-pass metabolism.
Formula:C22H38O5Purezza:Min. 95%Colore e forma:Colorless Clear LiquidPeso molecolare:382.53 g/molRef: 3D-FM46798
Prodotto fuori produzione
