CAS 59401-28-4

fattore di accoppiamento alfa(1) di Saccharomyces cerevisiae

Descrizione:

Il fattore di accoppiamento alfa(1), noto anche come alfa-factor, è un feromone peptidico prodotto dal lievito Saccharomyces cerevisiae, specificamente da cellule di tipo di accoppiamento alfa. Questa molecola di segnalazione gioca un ruolo cruciale nel processo di accoppiamento del lievito facilitando la comunicazione tra i diversi tipi di accoppiamento (alfa e a). La struttura dell'alfa-factor consiste in una catena corta di amminoacidi, tipicamente composta da circa 12 residui, che include una struttura ciclica unica che ne migliora la stabilità e l'attività biologica. Il feromone si lega a recettori specifici sulle cellule a, innescando una cascata di risposte cellulari che portano all'accoppiamento e alla fusione dei due tipi di cellule. L'alfa-factor è anche utilizzato in varie applicazioni biotecnologiche, inclusa la genetica dei lieviti e i processi di fermentazione. Il suo numero CAS, 59401-28-4, lo identifica nei database chimici, aiutando nella ricerca e nello sviluppo. In generale, il fattore di accoppiamento alfa(1) è essenziale per il ciclo riproduttivo del lievito e funge da modello per lo studio della segnalazione cellulare e della comunicazione negli organismi eucarioti.

Formula: C₈₂H₁₁₄N₂₀O₁₇S

InChI: InChI=1/C82H114N20O17S/c1-45(2)34-61(98-76(112)63(38-49-41-89-56-17-9-7-15-53(49)56)99-77(113)64(39-50-42-87-44-91-50)96-71(107)54(84)37-48-40-88-55-16-8-6-14-52(48)55)74(110)93-57(25-27-68(85)104)72(108)97-62(35-46(3)4)75(111)95-59(18-10-11-30-83)80(116)101-31-12-19-66(101)78(114)90-43-70(106)92-60(26-28-69(86)105)81(117)102-32-13-20-67(102)79(115)94-58(29-33-120-5)73(109)100-65(82(118)119)36-47-21-23-51(103)24-22-47/h6-9,14-17,21-24,40-42,44-46,54,57-67,88-89,103H,10-13,18-20,25-39,43,83-84H2,1-5H3,(H2,85,104)(H2,86,105)(H,87,91)(H,90,114)(H,92,106)(H,93,110)(H,94,115)(H,95,111)(H,96,107)(H,97,108)(H,98,112)(H,99,113)(H,100,109)(H,118,119)/t54-,57-,58-,59-,60-,61-,62-,63-,64-,65-,66-,67-/m0/s1

SMILES: CC(C)C[C@@H](C(=N[C@@H](CCC(=N)O)C(=N[C@@H](CC(C)C)C(=N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=NCC(=N[C@@H](CCC(=N)O)C(=O)N1CCC[C@H]1C(=N[C@@H](CCSC)C(=N[C@@H](Cc1ccc(cc1)O)C(=O)O)O)O)O)O)O)O)O)N=C([C@H](Cc1c[nH]c2ccccc12)N=C([C@H](Cc1cnc[nH]1)N=C([C@H](Cc1c[nH]c2ccccc12)N)O)O)O

Sinonimi:

• H-Trp-His-Trp-Leu-Gln-Leu-Lys-Pro-Gly-Gln-Pro-Met-Tyr-OH
• Mating Factor .alpha.
• a-Mating Factor, Yeast
• alpha1-Mating factor Saccharomyces cerevisiae
• L-tryptophyl-L-histidyl-L-tryptophyl-L-leucyl-L-glutaminyl-L-leucyl-L-lysyl-L-prolylglycyl-L-glutaminyl-L-prolyl-L-methionyl-L-tyrosine
• Trp-His-Trp-Leu-Gln-Leu-Lys-Pro-Gly-Gln-Pro-Met-Tyr

α-Mating Factor, yeast

CAS: 59401-28-4

alpha-Mating Factor, yeast

Formula: C₈₂H₁₁₄N₂₀O₁₇S

Peso molecolare: 1684.2

Ref: 02-J66502

Mating Factor α

CAS: 59401-28-4

Mating pheromone of mating type α cells of S. cerevisiae. This factor inhibits DNA synthesis, thereby preventing cell division of mating type a cells. The hydrophobic peptide binds to a class D G-protein-coupled receptor Ste2p.

Formula: C₈₂H₁₁₄N₂₀O₁₇S

Purezza: 98.4%

Colore e forma: White Powder

Peso molecolare: 1684.01

Ref: 01-4003514

L-Tryptophyl-L-histidyl-L-tryptophyl-L-leucyl-L-glutaminyl-L-leucyl-L-lysyl-L-prolylglycyl-L-glutaminyl-L-prolyl-L-methionyl-L-tyrosine

CAS: 59401-28-4

Formula: C₈₂H₁₁₄N₂₀O₁₇S

Purezza: 98%

Peso molecolare: 1683.9714

Ref: IN-DA01EO0Y

α-Factor Mating Pheromone, yeast

CAS: 59401-28-4

Alpha factor mating pheromone is a peptide of 13 amino acids secreted by Saccharomyces cerevisiae α cells.

Formula: C₈₂H₁₁₄N₂₀O₁₇S

Purezza: 98%

Colore e forma: White Powder

Peso molecolare: 1684

Ref: TM-TP1106

Alpha-Mating Factor

CAS: 59401-28-4

Alpha-Mating Factor is a peptide that belongs to the group of ligands. It has been shown to bind to the androgen receptor with high affinity and act as an activator for this receptor. Alpha-Mating Factor is also able to bind to the beta-adrenergic receptor. This protein has been shown to have ion channel activity, which may be due to its inhibition of potassium channels. Alpha-Mating Factor is used in research as a tool for studying cell biology and cell signalling pathways.

Formula: C₈₂H₁₁₄N₂₀O₁₇S

Purezza: Min. 95%

Peso molecolare: 1,684 g/mol

Ref: 3D-PMF-4076-V

α-Factor

CAS: 59401-28-4

The alpha factor pheromone arrests yeast in the G1 phase of their cell cycle, this allows the opposite mating type cells to synchronise. Alpha factor mating pheromone induces the expression of mating genes, changes in nuclear architecture, and polarizes growth toward the mating partner. STE2 encodes the alpha factor pheromone transmembrane G-protein coupled receptor (GPCR) found on mating-type-A cells in yeast. Alpha factor binds Ste2 and activates prototypic mitogen-activated protein kinase (MAPK) cascade. The dose of pheromone exposure differentially activates the MAPK Fus3 for alternate effects. A high dose of alpha factor leads to growth arrest and schmooing formation for mating, a lower dose causes elongated cell growth.

Formula: C₈₂H₁₁₄N₂₀O₁₇S

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 1,683.97 g/mol

Ref: 3D-CRB1000148

Mating factor α trifluoroacetate

CAS: 59401-28-4

Mating factor α trifluoroacetate is a research tool with CAS No. 59401-28-4 that is used in Cell Biology, Pharmacology, and Ion channels. Mating factor α trifluoroacetate inhibits ligand binding to receptor by competing with the natural substrate for the active site. It has been shown to be an activator of ion channels, which allow ions to flow through the cell membrane. Mating factor α trifluoroacetate can also be used as a research tool in antibody production and protein interactions.

Formula: C₈₂H₁₁₄N₂₀O₁₇S

Purezza: Min. 95%

Peso molecolare: 1,684.01 g/mol

Ref: 3D-JCA40128

Mating Factor a trifluoroacetate salt

CAS: 59401-28-4

Please enquire for more information about Mating Factor a trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page

Formula: C₈₂H₁₁₄N₂₀O₁₇S·xC₂HF₃O₂

Purezza: Min. 95%

Peso molecolare: 1,683.97 g/mol

Ref: 3D-FM108804