CAS 59721-29-8

Mesilato di camostat

Descrizione:

Mesilato di camostat è un inibitore sintetico della serina proteasi noto principalmente per il suo ruolo nell'inibire l'attività dell'enzima tripsina. È caratterizzato dalla sua capacità di modulare vari processi fisiologici, in particolare nel contesto delle malattie infiammatorie e delle infezioni virali. Il composto è spesso studiato per i suoi potenziali effetti terapeutici contro condizioni come la pancreatite e la fibrosi. Mesilato di camostat ha attirato attenzione per la sua possibile efficacia contro alcune infezioni virali, comprese quelle causate dai coronavirus, a causa del suo meccanismo d'azione che può interferire con l'ingresso virale nelle cellule ospiti. In termini di proprietà fisiche, è tipicamente presentato come una polvere cristallina bianca o bianco sporco, solubile in acqua e in vari solventi organici. La sostanza è somministrata per via orale e ha una vita media relativamente breve, richiedendo una considerazione attenta dei regimi di dosaggio nelle applicazioni cliniche. In generale, Mesilato di camostat rappresenta un candidato promettente nella ricerca farmacologica, in particolare nei campi della virologia e dell'infiammazione.

Formula: C₂₀H₂₂N₄O₅·CH₄O₃S

InChI: InChI=1S/C20H22N4O5.CH4O3S/c1-24(2)17(25)12-28-18(26)11-13-3-9-16(10-4-13)29-19(27)14-5-7-15(8-6-14)23-20(21)22;1-5(2,3)4/h3-10H,11-12H2,1-2H3,(H4,21,22,23);1H3,(H,2,3,4)

InChI key: InChIKey=FSEKIHNIDBATFG-UHFFFAOYSA-N

SMILES: C(OC1=CC=C(CC(OCC(N(C)C)=O)=O)C=C1)(=O)C2=CC=C(NC(=N)N)C=C2.S(C)(=O)(=O)O

Sinonimi:

• 2-(Dimethylamino)-2-oxoethyl 4-(4-guanidinobenzoyloxy)phenylacetate methanesulphonate
• Benzeneacetic acid, 4-[[4-[(aminoiminomethyl)amino]benzoyl]oxy]-, 2-(dimethylamino)-2-oxoethyl ester, methanesulfonate (1:1)
• Benzeneacetic acid, 4-[[4-[(aminoiminomethyl)amino]benzoyl]oxy]-, 2-(dimethylamino)-2-oxoethyl ester, monomethanesulfonate
• Camostat mesylate
• Camostat monomethanesulfonate
• Foipan
• Foy 305
• Foy-S 980
• N-(diaminomethylidene)-4-[(4-{2-[2-(dimethylamino)-2-oxoethoxy]-2-oxoethyl}phenoxy)carbonyl]anilinium methanesulfonate

Camostat Mesylate

CAS: 59721-28-7, 59721-29-8

Formula: C₂₀H₂₂N₄O₅·CH₄O₃S

Purezza: >98.0%(HPLC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 494.52

Ref: 3B-C2977

Camostat methanesulfate, 98%

CAS: 59721-29-8

An orally active synthetic serine protease inhibitor

Formula: C₂₀H₂₂N₄O₅·CH₃SO₃H

Purezza: 98%

Colore e forma: White to cream, Powder

Peso molecolare: 494.52

Ref: 02-J62362

Camostat mesylate

CAS: 59721-29-8

Camostat mesylate

Purezza: ≥98%

Peso molecolare: 494.52g/mol

Ref: 54-BUP17156

Camostat mesylate

CAS: 59721-29-8

Camostat mesylate

Formula: C₂₀H₂₂N₄O₅·CH₃SO₃H

Purezza: 99.77% (Typical Value in Batch COA)

Colore e forma: white solid

Peso molecolare: 494.52g/mol

Ref: 54-BISN0316

Camostat mesylate

CAS: 59721-29-8

Formula: C₂₀H₂₂N₄O₅·CH₃SO₃H

Purezza: ≥ 98.0%

Colore e forma: White crystalline powder or crystals

Peso molecolare: 494.52

Ref: 7W-GP4306

Camostat Mesylate

CAS: 59721-29-8

Formula: C₂₀H₂₂N₄O₅·CH₄O₃S

Colore e forma: White To Off-White Solid

Peso molecolare: 398.42 96.10

Ref: 4Z-C-131001

Camostat mesylate

CAS: 59721-29-8

Camostat mesylate (FOY-S980) is a trypsin-like protease inhibitor and inhibits airway epithelial sodium channel (ENaC) function.

Formula: C₂₁H₂₆N₄O₈S

Purezza: 99.31% - 99.85%

Colore e forma: Crystalline Solid

Peso molecolare: 494.52

Ref: TM-T2391

Camostat Mesilate RS

CAS: 59721-29-8

Colore e forma: White

Ref: 2K-1037000021

Camostat mesylate

CAS: 59721-29-8

Camostat mesylate is an inhibitor of trypsin-like serine proteases such as trypsin, thrombin, plasmin, plasma kallikrein and urokinase-type plasminogen activator. Camostat mesylate has also been shown to inhibit trimming of the viral spike (S) protein in coronaviruses. Camostat mesylate inhibited the entry of SARS-CoV-2 in lung cells by inhibiting the priming process of S-protein, necessary for the viral entry into host cells.

Formula: C₂₀H₂₂N₄O₅•CH₄O₃S

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 494.52 g/mol

Ref: 3D-FC19641

Camostat mesylate - Bio-X ™

CAS: 59721-29-8

Camostat is a serine protease inhibitor that is used for the treatment of chronic pancreatitis. This drug has shown to reduce inflammation and pain. Studies have shown that Camostat has also inhibited the entry of SARS-CoV-2 in lung cells by inhibiting the priming process of S-protein, necessary for the viral entry into host cells.

Formula: C₂₀H₂₂N₄O₅•CH₄O₃S

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 494.52 g/mol

Ref: 3D-BC164270

Camostat Mesilate

CAS: 59721-29-8

Camostat mesilate is a prodrug that is metabolized to the active form, pemastatin. It is used for the treatment of bowel disease and squamous cell carcinoma. Camostat mesilate inhibits the TNF-α receptor by binding to its response element in vitro and in vivo. The biological properties of camostat mesilate are due to its ability to inhibit TNF-α production by binding to the TNF-α receptor, thereby preventing activation of transcription factors such as nuclear factor kappa B (NFκB). In vitro assays have shown that camostat mesilate induces apoptosis in human carcinoma cell lines through inhibition of growth factor-β1. This drug has also been shown to be effective in treating viral infections, including HIV and herpes zoster.

Formula: C₂₀H₂₂N₄O₅•CH₃SO₃H

Purezza: Min. 95%

Peso molecolare: 494.5 g/mol

Ref: 3D-ISP-3606-PI

4-(2-(2-(Dimethylamino)-2-oxoethoxy)-2-oxoethyl)phenyl 4-guanidinobenzoate methanesulfonate

CAS: 59721-29-8

Purezza: 99%

Peso molecolare: 494.519989

Ref: 10-F868964

Camostat Mesylate-D4

Prodotto controllato

CAS: 59721-29-8

Applications Camostat mesylate-D4 is a labelled analogue of Camostat mesylate (C150300).

Formula: C₂₀H₁₈D₄N₄O₅•CH₄O₃S

Colore e forma: Neat

Peso molecolare: 402.44 + 96.11

Ref: TR-C150303

Camostat Mesylate-D6

Prodotto controllato

CAS: 59721-29-8

Formula: C₂₀H₁₆D₆N₄O₅•CH₃SO₃H

Colore e forma: Neat

Peso molecolare: 500.56

Ref: TR-C150302

Camostat Mesylate

Prodotto controllato

CAS: 59721-29-8

Formula: C₂₀H₂₂N₄O₅·CH₄O₃S

Colore e forma: Neat

Peso molecolare: 494.52

Ref: TR-C150300