CAS 59880-97-6

N-Formil-L-metionil-L-leucil-L-fenilalanina

Descrizione:

N-Formil-L-metionil-L-leucil-L-fenilalanina, con il numero CAS 59880-97-6, è un peptide sintetico che consiste in tre aminoacidi: metionina, leucina e fenilalanina, con un gruppo formile attaccato al terminus amino del residuo di metionina. Questo composto è caratterizzato dalla sua specifica sequenza di aminoacidi, che contribuisce alla sua attività biologica e potenziali applicazioni nella ricerca biochimica. Peptidi come questo spesso mostrano proprietà come solubilità in solventi polari, stabilità in condizioni fisiologiche e la capacità di interagire con recettori biologici o enzimi. La presenza del gruppo formile può influenzare la reattività del peptide e il suo ruolo in vari percorsi biochimici. N-Formil-L-metionil-L-leucil-L-fenilalanina può anche servire come composto modello per studiare la sintesi di peptidi, le relazioni struttura-attività e i meccanismi di segnalazione mediati da peptidi nei sistemi biologici. La sua struttura unica lo rende un argomento di interesse in campi come la chimica medicinale e la farmacologia.

Formula: C₈H₁₂ClNO

InChI: InChI=1/C21H31N3O5S/c1-14(2)11-17(23-19(26)16(22-13-25)9-10-30-3)20(27)24-18(21(28)29)12-15-7-5-4-6-8-15/h4-8,13-14,16-18H,9-12H2,1-3H3,(H,22,25)(H,23,26)(H,24,27)(H,28,29)/t16-,17-,18-/m0/s1

InChI key: InChIKey=PRQROPMIIGLWRP-BZSNNMDCSA-N

SMILES: [C@H](C(N[C@@H](CC1=CC=CC=C1)C(O)=O)=O)(NC([C@H](CCSC)NC=O)=O)CC(C)C

Sinonimi:

• 3: PN: WO2010089019 PAGE: 22 claimed protein
• 4-(2-Aminoethyl)Phenol Hydrochloride (1:1)
• 4-Hydroxy-phenethylamine hydrochloride
• <span class="text-smallcaps">L</smallcap>-Phenylalanine, N-[N-(N-formyl-<smallcap>L</smallcap>-methionyl)-<smallcap>L</span>-leucyl]-
• <span class="text-smallcaps">L</smallcap>-Phenylalanine, N-formyl-<smallcap>L</smallcap>-methionyl-<smallcap>L</span>-leucyl-
• For-Met-Leu-Phe-OH
• Formyl-Met-Leu-Phe-OH
• N-Formyl-<span class="text-smallcaps">L</smallcap>-methionyl-<smallcap>L</smallcap>-leucyl-<smallcap>L</span>-phenylalanine
• N-Formyl-Met-Leu-Phe
• N-Formyl-Met-Leu-Phe-OH
• N-Formyl-methionyl-leucyl-phenylalanine
• N-formylmethionylleucylphenylalanine
• NSC 350593
• L-Phenylalanine, N-formyl-L-methionyl-L-leucyl-
• L-Phenylalanine, N-[N-(N-formyl-L-methionyl)-L-leucyl]-
• N-Formyl-L-methionyl-L-leucyl-L-phenylalanine
• fMLF
• 4-HYDROXYPHENYLETHYLAMINE HCL
• 4-HYDROXYPHENETHYLAMINE HYDROCHLORIDE
• fMLP (misnomer but widely used)
• F-MET-LEU-PHE
• TYRAMINE MONOHYDROCHLORIDE
• 4-(2-AMINOETHYL)PHENOL HYDROCHLORIDE
• P-HYDROXYPHENETHYLAMINE HYDROCHLORIDE
• TYRAMINE HCL(P)
• TYRAMINE HCL
• TIMTEC-BB SBB003808
• P-(2-AMINOETHYL)PHENOL HYDROCHLORIDE
• 2-(4-HYDROXYPHENYL)ETHYLAMMONIUM CHLORIDE
• TYROSAMINE HCL
• TYROSAMINE HYDROCHLORIDE
• TYRAMINE
• 2-(4-HYDROXYPHENYL)ETHYLAMINE HYDROCHLORIDE
• 4-HYDROXYPHENYLETHYLAMINE HYDROCHLORIDE
• 2-(4-HYDROXYPHENYL)ETHYLAMINE HCL

N-Formyl-L-methionyl-L-leucyl-L-phenylalanine

CAS: 59880-97-6

Formula: C₂₁H₃₁N₃O₅S

Purezza: >98.0%(HPLC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 437.56

Ref: 3B-F1158

Chemotactic Peptide

CAS: 59880-97-6

For cellular and molecular biology applications

Formula: C₂₁H₃₁N₃O₅S

Colore e forma: White to pale cream, Lyophilized Powder

Peso molecolare: 437.56

Ref: 02-J65184

For-Met-Leu-Phe-OH

CAS: 59880-97-6

There is evidence that pretreatment of human polymorphonuclear neutrophils (PMN) with fMLF results in the inhibition of TNF-α secretion, which indicates that this typical proinflammatory agent could play, at least at determined conditions, an antiinflammatory role.

Formula: C₂₁H₃₁N₃O₅S

Purezza: 99.7%

Colore e forma: White Powder

Peso molecolare: 437.56

Ref: 01-4001509

TYRAMINE HYDROCHLORIDE

CAS: 59880-97-6

Formula: C₂₁H₃₁N₃O₅S

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 437.5529

Ref: IN-DA00E9MC

N-Formyl-Met-Leu-Phe

CAS: 59880-97-6

N-Formyl-Met-Leu-Phe

Purezza: ≥95%

Peso molecolare: 437.55g/mol

Ref: 54-BUP06404

N-Formyl-Met-Leu-Phe

CAS: 59880-97-6

Formula: C₂₁H₃₁N₃O₅S

Peso molecolare: 437.55

Ref: 7W-GL6160

N-formyl-[U-13C-15N]-Met-Leu-Phe-OH

CAS: 59880-97-6

N-formyl-[U-13C-15N]-Met-Leu-Phe-OH

Purezza: 98%

Peso molecolare: 437.55g/mol

Ref: 54-OR1023295

N-Formyl-Met-Leu-Phe

CAS: 59880-97-6

N-Formyl-Met-Leu-Phe (N-Formyl-MLF) (fMLF) is a synthetic peptide that acts as an agonist at formyl peptide receptors (FPR; Ki = 0.8 pM).

Formula: C₂₁H₃₁N₃O₅S

Purezza: 98.69% - ≥95%

Colore e forma: Solid

Peso molecolare: 437.55

Ref: TM-T7091

Chemotactic Peptide

CAS: 59880-97-6

As a chemotactic peptide, For-Met-Leu-Phe (FMLP) has chemotactic properties, which means it can attract cells. For example it is a chemoattractant for phagocytic leukocytes and neutrophils. Neutrophils which have seven transmembrane G-protein coupled receptors are activated during the acute inflammatory response by FMLP and other chemotactic factors which bind to its surface receptors. This results in the activate of NF- κB, MAPK and PI3K pathways. In particular FMLP is known to induce Interleukin-8 (IL-8) which is responsible for both tissue damage and the pathogenesis of inflammatory processes resulting from neutrophils. Chemotactic peptide have been used to study the function of polymorphonuclear leukocytes and other white blood cells in inflammation. Chemotactic peptides are often used as fluorescent probes to measure intracellular metabolic responses to chemoattractant stimulation.
This product is available as a 0.5mg vial.

Formula: C₂₁H₃₁N₃O₅S

Purezza: Min. 95%

Peso molecolare: 437.55 g/mol

Ref: 3D-PCT-4066-V

N-Formyl-Met-Leu-Phe

CAS: 59880-97-6

Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool

Formula: C₂₁H₃₁N₃O₅S

Peso molecolare: 437.6 g/mol

Ref: 3D-PP50655

N-Formyl-Met-Leu-Phe

Prodotto controllato

CAS: 59880-97-6

Applications N-Formyl-Met-Leu-Phe is an inducer of superoxide release and agonist for FPR1.

Formula: C₂₁H₃₁N₃O₅S

Colore e forma: Neat

Peso molecolare: 437.55

Ref: TR-F700713

Chemotactic Peptide

CAS: 59880-97-6

Chemotactic peptides are peptides that possess chemotactic properties, which means they attract cells. One well-known chemotactic peptide is For-Met-Leu-Phe (FMLP) and is a chemoattractant for phagocytic leukocytes and neutrophils. During the acute inflammatory response chemotactic factors activate neutrophils which have seven transmembrane G-protein coupled receptors. FMLP bind to these G-protein coupled receptors on the surface of neutrophils and activate NF- κB, MAPK and PI3K pathways. In particular FMLP is known to induce Interleukin-8 (IL-8) which is responsible for both tissue damage and the pathogenesis of inflammatory processes resulting from neutrophils. Chemotactic peptide have been used to study the function of polymorphonuclear leukocytes and other white blood cells in inflammation. Chemotactic peptides are often used as fluorescent probes to measure intracellular metabolic responses to chemoattractant stimulation.

Formula: C₂₁H₃₁N₃O₅S

Purezza: Min. 95%

Peso molecolare: 437.55 g/mol

Ref: 3D-PCT-4066